D008239Chemicals & DrugsD12.125.068.555D12.125.095.647D12.125.142.497891470.919852Lysineprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMolecular Genetics and Cell Biology30420515Katafuchi T, Holland WL, Kollipara RK, Kittler R, Mangelsdorf DJ, Kliewer SAProceedings of the National Academy of Sciences of the United States of AmericaPPAR?-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):12102-12111.Proc Natl Acad Sci U S A2018-11-12T00:00:002018PPAR?-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice.RaghuMirmiraRaghu Mirmira41.7886000000000087.598699999999993890Mirmira, RaghuProfessor30661771Ganapathi M, Padgett LR, Yamada K, Devinsky O, Willaert R, Person R, Au PB, Tagoe J, McDonald M, Karlowicz D, Wolf B, Lee J, Shen Y, Okur V, Deng L, LeDuc CA, Wang J, Hanner A, Mirmira RG, Park MH, Mastracci TL, Chung WKAmerican journal of human geneticsRecessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. Am J Hum Genet. 2019 02 07; 104(2):287-298.Am J Hum Genet2019-01-17T00:00:002019Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.31796630Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, Tersey SA, Mirmira RGScience signalingHypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis. Sci Signal. 2019 12 03; 12(610).Sci Signal2019-12-03T00:00:002019Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.32208453Mastracci TL, Colvin SC, Padgett LR, Mirmira RGPloS oneHypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes. PLoS One. 2020; 15(3):e0230627.PLoS One2020-03-24T00:00:002020Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes.33326776Gobert AP, Finley JL, Latour YL, Asim M, Smith TM, Verriere TG, Barry DP, Allaman MM, Delagado AG, Rose KL, Calcutt MW, Schey KL, Sierra JC, Piazuelo MB, Mirmira RG, Wilson KTCell reportsHypusination Orchestrates the Antimicrobial Response of Macrophages. Cell Rep. 2020 12 15; 33(11):108510.Cell Rep2020-12-15T00:00:002020Hypusination Orchestrates the Antimicrobial Response of Macrophages.Ben May Department of Cancer Researchhttp://www.ruthenlab.orgruthenlab.org2.936710.0037442389research area of0.7963410.00481121153subject area forBen May DepartmentMedicineUniversity of ChicagoAlexander J.Ruthenburg1nB8H6kQF+7Mg31EdUXm+mb7+MTz7LFLAlexander J. Ruthenburg41.78927490000000-87.601250000000001716Ruthenburg, Alexander J.Associate ProfessorZhong-YuXieZhong-Yu Xie41.78927490000000-87.601250000000002336Xie, Zhong-YuPostdoctoral ScholarYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorYingmingZhaoYingming Zhao41.78927490000000-87.6012500000000073Zhao, YingmingProfessortrue1Postdoctoral ScholarPostdoctoral Scholartrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorMedicine-Endocrinology