D017997Chemicals & DrugsD10.251.355.255.100.450.855.455D10.251.355.310.166.887.855.455D23.469.050.175.450.725.4004210.996472Leukotriene C4plugins:FeaturedPresentationsFeatured Presentationsplugins:FeaturedVideosFeatured Videosprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson10516222Muñoz NM, Hamann KJ, Rabe KF, Sano H, Zhu X, Leff ARThe American journal of physiologyAugmentation of eosinophil degranulation and LTC(4) secretion by integrin-mediated endothelial cell adhesion. Am J Physiol. 1999 10; 277(4):L802-10.Am J Physiol1999-10-01T00:00:001999Augmentation of eosinophil degranulation and LTC(4) secretion by integrin-mediated endothelial cell adhesion.12897749Meliton AY, Muñoz NM, Liu J, Lambertino AT, Boetticher E, Myo S, Myou S, Zhu X, Johnson M, Leff ARThe Journal of allergy and clinical immunologyBlockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils. J Allergy Clin Immunol. 2003 Aug; 112(2):404-10.J Allergy Clin Immunol2003-08-01T00:00:002003Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils.Medicine-Pulmonary and Critical Care16785555Muñoz NM, Meliton AY, Lambertino A, Boetticher E, Learoyd J, Sultan F, Zhu X, Cho W, Leff ARJournal of immunology (Baltimore, Md. : 1950)Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils. J Immunol. 2006 Jul 01; 177(1):574-82.J Immunol2006-07-01T00:00:002006Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils.10351938Sano A, Muñoz NM, Sano H, Choi J, Zhu X, Jacobs B, Leff ARAmerican journal of respiratory and critical care medicineInhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils. Am J Respir Crit Care Med. 1999 Jun; 159(6):1903-9.Am J Respir Crit Care Med1999-06-01T00:00:001999Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils.10835322Muñoz NM, van Seventer GA, Semnani RT, Leff ARAmerican journal of physiology. Lung cellular and molecular physiologyAugmentation of LTC(4) synthesis in human eosinophils caused by CD3-stimulated Th2-like cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2000 Jun; 278(6):L1172-9.Am J Physiol Lung Cell Mol Physiol2000-06-01T00:00:002000Augmentation of LTC(4) synthesis in human eosinophils caused by CD3-stimulated Th2-like cells in vitro.https://biomedsciences.uchicago.edu/page/anne-i-sperling-phdUChicago Bio0.6140830.007482924research area of0.2923710.030037717subject area forMedicineUniversity of ChicagoAnne I.SperlingAnne I. Sperling41.78927490000000-87.601250000000001999Sperling, Anne I.ProfessorStevenWhiteSteven White41.78927490000000-87.601250000000002172White, StevenProfessorAlanLeffAlan Leff41.78927490000000-87.601250000000002537Leff, AlanEmeritus/EmeritaMary ElizabethStrekMary Elizabeth Strek41.78927490000000-87.601250000000002563Strek, Mary ElizabethProfessortrue1Emeritus/EmeritaEmeritus/Emeritatrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor