Nancy Jean Cox to Diabetes Mellitus, Type 2
This is a "connection" page, showing publications Nancy Jean Cox has written about Diabetes Mellitus, Type 2.
Connection Strength
3.625
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Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. Am J Hum Genet. 2014 Nov 06; 95(5):521-34.
Score: 0.243
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Genetic risk factors for type 2 diabetes: a trans-regulatory genetic architecture? Am J Hum Genet. 2012 Sep 07; 91(3):466-77.
Score: 0.210
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Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10. Diabetes. 2005 Dec; 54(12):3573-6.
Score: 0.131
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Linkage of calpain 10 to type 2 diabetes: the biological rationale. Diabetes. 2004 Feb; 53 Suppl 1:S19-25.
Score: 0.116
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A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes. Nat Metab. 2023 02; 5(2):237-247.
Score: 0.108
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Calpain 10 and genetics of type 2 diabetes. Curr Diab Rep. 2002 Apr; 2(2):186-90.
Score: 0.102
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Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene. Hum Mol Genet. 2001 Oct 01; 10(20):2301-5.
Score: 0.098
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019 06; 570(7759):71-76.
Score: 0.083
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Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nat Genet. 1999 Feb; 21(2):213-5.
Score: 0.082
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Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. PLoS Med. 2018 08; 15(8):e1002642.
Score: 0.079
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Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):379-384.
Score: 0.076
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2017 12 19; 4:170179.
Score: 0.076
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Diabetes, dependence, asymptotics, selection and significance. Nat Genet. 1997 Oct; 17(2):148.
Score: 0.074
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017 07; 66(7):2019-2032.
Score: 0.072
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The genetic architecture of type 2 diabetes. Nature. 2016 08 04; 536(7614):41-47.
Score: 0.068
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Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas. Cardiovasc Diabetol. 2016 Jun 08; 15:86.
Score: 0.068
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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 05 15; 25(10):2070-2081.
Score: 0.067
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Localization of MODY3 to a 5-cM region of human chromosome 12. Diabetes. 1995 Dec; 44(12):1408-13.
Score: 0.066
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015 Jan; 11(1):e1004876.
Score: 0.062
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Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 2015 May; 64(5):1853-66.
Score: 0.061
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar; 46(3):234-44.
Score: 0.058
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Maternal component in NIDDM transmission. How large an effect? Diabetes. 1994 Jan; 43(1):166-8.
Score: 0.057
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Genome wide association studies for diabetes: perspective on results and challenges. Pediatr Diabetes. 2013 Mar; 14(2):90-6.
Score: 0.054
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Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes. Genet Epidemiol. 2012 Dec; 36(8):820-8.
Score: 0.052
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Mapping diabetes-susceptibility genes. Lessons learned from search for DNA marker for maturity-onset diabetes of the young. Diabetes. 1992 Apr; 41(4):401-7.
Score: 0.051
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Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry. Cancer Epidemiol Biomarkers Prev. 2012 Mar; 21(3):552-6.
Score: 0.050
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Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. Diabetologia. 2011 Aug; 54(8):2047-55.
Score: 0.048
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Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas. Diabetologia. 2011 Aug; 54(8):2038-46.
Score: 0.048
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Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1484-8.
Score: 0.047
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Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60. Transl Res. 2010 Jul; 156(1):7-14.
Score: 0.044
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Linkage studies on NIDDM and the insulin and insulin-receptor genes. Diabetes. 1989 May; 38(5):653-8.
Score: 0.042
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Glucose transporter gene and non-insulin-dependent diabetes. Lancet. 1988 Oct 01; 2(8614):793-4.
Score: 0.040
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Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes. 2007 Dec; 56(12):3033-44.
Score: 0.037
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A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2. Diabetologia. 2007 Jul; 50(7):1418-22.
Score: 0.036
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Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium. Hum Hered. 2008; 66(1):35-49.
Score: 0.036
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Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects. Diabetes. 2006 Aug; 55(8):2379-86.
Score: 0.034
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Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. Mol Genet Metab. 2006 Sep-Oct; 89(1-2):174-84.
Score: 0.034
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Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes. Diabetologia. 2006 Jul; 49(7):1560-6.
Score: 0.034
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The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia. 2005 Oct; 48(10):2018-24.
Score: 0.032
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Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene. Hum Genet. 2005 Jul; 117(2-3):258-66.
Score: 0.032
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Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J Hum Genet. 2005; 50(2):92-98.
Score: 0.031
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Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. Diabetes. 2004 Jun; 53(6):1609-13.
Score: 0.030
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Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab. 2004 Feb; 81(2):122-6.
Score: 0.029
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Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects. Diabetes. 2003 Jan; 52(1):209-13.
Score: 0.027
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Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes. 2002 Dec; 51(12):3561-7.
Score: 0.027
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Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Jun; 87(6):2606-10.
Score: 0.026
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Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Apr; 87(4):1669-73.
Score: 0.025
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Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet. 2002 May; 70(5):1096-106.
Score: 0.025
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Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab. 2002 Feb; 87(2):650-4.
Score: 0.025
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Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet. 2001 Sep; 69(3):544-52.
Score: 0.024
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Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis. Lupus. 2021 Jul; 30(8):1264-1272.
Score: 0.024
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Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects. Diabetes. 2001 Mar; 50(3):694-6.
Score: 0.024
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beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY. Diabetes. 2000 Nov; 49(11):1955-7.
Score: 0.023
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PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records. J Am Med Inform Assoc. 2020 11 01; 27(11):1675-1687.
Score: 0.023
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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct; 26(2):163-75.
Score: 0.023
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A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest. 2000 Oct; 106(7):R69-73.
Score: 0.023
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Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis. Arthritis Rheumatol. 2020 09; 72(9):1483-1492.
Score: 0.023
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No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY. Diabetologia. 2000 Aug; 43(8):1064-9.
Score: 0.023
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Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3beta gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young. Diabetes. 2000 Feb; 49(2):302-5.
Score: 0.022
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Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet. 1997 Nov; 61(5):1179-88.
Score: 0.019
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Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet. 1997 Aug; 61(2):423-9.
Score: 0.018
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The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships. Diabetes. 1997 Jul; 46(7):1227-9.
Score: 0.018
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature. 1996 Dec 05; 384(6608):455-8.
Score: 0.018
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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1) Nature. 1996 Dec 05; 384(6608):458-60.
Score: 0.018
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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet. 1996 Jun; 13(2):161-6.
Score: 0.017
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Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle. Diabetologia. 1996 Jun; 39(6):725-30.
Score: 0.017
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A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):3937-41.
Score: 0.017
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An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM. Diabetes. 1996 Mar; 45(3):291-4.
Score: 0.017
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Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese. Diabetes. 1996 Feb; 45(2):267-9.
Score: 0.017
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Linkage studies in NIDDM with markers near the sulphonylurea receptor gene. Diabetologia. 1995 Dec; 38(12):1479-81.
Score: 0.016
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Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs. Diabetes. 1995 Aug; 44(8):999-1001.
Score: 0.016
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Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM. Diabetes. 1995 May; 44(5):592-6.
Score: 0.016
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Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature. 2014 Mar 20; 507(7492):371-5.
Score: 0.015
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Importance sampling. I. Computing multimodel p values in linkage analysis. Am J Hum Genet. 1992 Dec; 51(6):1413-29.
Score: 0.013
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Polymorphisms of GLUT2 and GLUT4 genes. Use in evaluation of genetic susceptibility to NIDDM in blacks. Diabetes. 1990 Dec; 39(12):1534-42.
Score: 0.012
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Reconstructability analysis as a tool for identifying gene-gene interactions in studies of human diseases. Stat Appl Genet Mol Biol. 2010; 9:Article18.
Score: 0.011
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Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome. Diabetes Res Clin Pract. 2009 Dec; 86(3):186-92.
Score: 0.011
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Insulin-receptor and apolipoprotein genes contribute to development of NIDDM in Chinese Americans. Diabetes. 1989 Jan; 38(1):17-23.
Score: 0.010
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[The association of non-insulin-dependent diabetes mellitus with the genes responsible for carbohydrate and lipid metabolism in the Chinese]. Zhonghua Yi Xue Za Zhi. 1988 Oct; 68(10):552-6, 38.
Score: 0.010
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Linkage studies of maturity onset diabetes of the young--R.W. pedigree. Diabetologia. 1988 Oct; 31(10):778.
Score: 0.010
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Methods for analysis and visualization of SNP genotype data for complex diseases. Pac Symp Biocomput. 2003; 548-61.
Score: 0.007
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Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Sep; 87(9):4297-300.
Score: 0.007
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A statistical method for identification of polymorphisms that explain a linkage result. Am J Hum Genet. 2002 Feb; 70(2):399-411.
Score: 0.006
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Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives. J Clin Endocrinol Metab. 2001 May; 86(5):2027-31.
Score: 0.006
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Sequential imputation for multilocus linkage analysis. Proc Natl Acad Sci U S A. 1994 Nov 22; 91(24):11684-8.
Score: 0.004