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Samuel Refetoff to Thyroid Gland

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This is a "connection" page, showing publications Samuel Refetoff has written about Thyroid Gland.
Samuel Refetoff
Connection Strength
7.319
Thyroid Gland
  1. Interconnection between circadian clocks and thyroid function. Nat Rev Endocrinol. 2019 10; 15(10):590-600.
    View in: PubMed
    Score: 0.523
  2. Homozygous Mutation in Human Serum Albumin and Its Implication on Thyroid Tests. Thyroid. 2018 06; 28(6):811-814.
    View in: PubMed
    Score: 0.481
  3. Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin. Thyroid. 2016 10; 26(10):1499-1512.
    View in: PubMed
    Score: 0.429
  4. A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis. J Clin Endocrinol Metab. 2007 Jul; 92(7):2816-20.
    View in: PubMed
    Score: 0.223
  5. Foxe1 deficiency impairs thyroid fate while supporting lung differentiation. EMBO Rep. 2026 08; 27(15):4462-4492.
    View in: PubMed
    Score: 0.211
  6. Thyroid Hormone Synthesis Without Thyroglobulin. Thyroid. 2026 04; 36(4):441-450.
    View in: PubMed
    Score: 0.206
  7. Stimulated thyroid hormone synthesis machinery drives thyrocyte cell death independent of ER stress. J Clin Invest. 2025 12 15; 135(24).
    View in: PubMed
    Score: 0.201
  8. Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis. JCI Insight. 2025 09 09; 10(17).
    View in: PubMed
    Score: 0.199
  9. A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion. Int J Mol Sci. 2025 Jul 24; 26(15).
    View in: PubMed
    Score: 0.198
  10. Resistance to thyroid hormone in a patient with thyroid dysgenesis. Thyroid. 2005 Jul; 15(7):730-3.
    View in: PubMed
    Score: 0.197
  11. Analysis of the PAX8 gene in congenital hypothyroidism caused by different forms of thyroid dysgenesis in a father and daughter. J Pediatr Endocrinol Metab. 2004 Jul; 17(7):1021-9.
    View in: PubMed
    Score: 0.184
  12. STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179. Nat Genet. 2024 May; 56(5):877-888.
    View in: PubMed
    Score: 0.182
  13. Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. JCI Insight. 2023 06 22; 8(12).
    View in: PubMed
    Score: 0.171
  14. Maintaining the thyroid gland in mutant thyroglobulin-induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood. J Biol Chem. 2022 07; 298(7):102066.
    View in: PubMed
    Score: 0.159
  15. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 2002 Apr; 143(4):1554-7.
    View in: PubMed
    Score: 0.157
  16. Thyroid function and effect of aging in combined hetero/homozygous mice deficient in thyroid hormone receptors alpha and beta genes. J Endocrinol. 2002 Jan; 172(1):177-85.
    View in: PubMed
    Score: 0.154
  17. XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes. Thyroid. 2022 02; 32(2):128-137.
    View in: PubMed
    Score: 0.154
  18. Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland. Endocrinology. 2001 Dec; 142(12):5131-9.
    View in: PubMed
    Score: 0.154
  19. Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels. Thyroid. 2021 01; 31(1):23-35.
    View in: PubMed
    Score: 0.140
  20. Nonautoimmune Hyperthyroidism Caused by a Somatic Mosaic GNAS Mutation Involving Part of the Thyroid Gland. Thyroid. 2020 04; 30(4):640-642.
    View in: PubMed
    Score: 0.135
  21. Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis. Thyroid. 2020 01; 30(1):133-146.
    View in: PubMed
    Score: 0.134
  22. NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland. Thyroid. 2018 06; 28(6):780-798.
    View in: PubMed
    Score: 0.120
  23. GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. J Clin Invest. 2017 12 01; 127(12):4326-4337.
    View in: PubMed
    Score: 0.116
  24. Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone. Thyroid. 1996 Dec; 6(6):589-93.
    View in: PubMed
    Score: 0.109
  25. Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 06 01; 143(11):1958-70.
    View in: PubMed
    Score: 0.104
  26. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model. Endocrinology. 2016 Apr; 157(4):1363-71.
    View in: PubMed
    Score: 0.102
  27. Thyroid function tests and characterization of thyroxine-binding globulin in the carbohydrate-deficient glycoprotein syndrome type I. J Clin Endocrinol Metab. 1995 Dec; 80(12):3744-9.
    View in: PubMed
    Score: 0.101
  28. Long-term outcome of loss-of-function mutations in thyrotropin receptor gene. Thyroid. 2015 Mar; 25(3):292-9.
    View in: PubMed
    Score: 0.096
  29. American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models. Thyroid. 2014 Jan; 24(1):88-168.
    View in: PubMed
    Score: 0.088
  30. Attention-deficit hyperactivity disorder and thyroid function. J Pediatr. 1993 Oct; 123(4):539-45.
    View in: PubMed
    Score: 0.087
  31. Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology. 2013 Jul; 154(7):2533-41.
    View in: PubMed
    Score: 0.085
  32. Generation of functional thyroid from embryonic stem cells. Nature. 2012 Nov 01; 491(7422):66-71.
    View in: PubMed
    Score: 0.081
  33. Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function. Endocrinology. 2012 Dec; 153(12):6145-54.
    View in: PubMed
    Score: 0.081
  34. Thyroid regeneration: characterization of clear cells after partial thyroidectomy. Endocrinology. 2012 May; 153(5):2514-25.
    View in: PubMed
    Score: 0.078
  35. Mice deficient in dual oxidase maturation factors are severely hypothyroid. Mol Endocrinol. 2012 Mar; 26(3):481-92.
    View in: PubMed
    Score: 0.078
  36. Inherited defects of thyroid hormone metabolism. Ann Endocrinol (Paris). 2011 Apr; 72(2):95-8.
    View in: PubMed
    Score: 0.074
  37. The coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlation. J Clin Endocrinol Metab. 2011 Jun; 96(6):E1001-6.
    View in: PubMed
    Score: 0.073
  38. Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion. J Clin Invest. 2010 Sep; 120(9):3377-88.
    View in: PubMed
    Score: 0.070
  39. Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis. Endocrinology. 2007 Dec; 148(12):5680-7.
    View in: PubMed
    Score: 0.057
  40. Effects of maternal levels of thyroid hormone (TH) on the hypothalamus-pituitary-thyroid set point: studies in TH receptor beta knockout mice. Endocrinology. 2007 Nov; 148(11):5305-12.
    View in: PubMed
    Score: 0.057
  41. Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats. Endocrinology. 2007 Oct; 148(10):4727-33.
    View in: PubMed
    Score: 0.057
  42. Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis. J Biol Chem. 2006 Feb 24; 281(8):5000-7.
    View in: PubMed
    Score: 0.051
  43. Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice. Am J Physiol Cell Physiol. 2006 Apr; 290(4):C1160-7.
    View in: PubMed
    Score: 0.051
  44. Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. Mol Endocrinol. 2005 Jul; 19(7):1779-91.
    View in: PubMed
    Score: 0.048
  45. RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor. Am J Physiol Endocrinol Metab. 2002 Aug; 283(2):E326-31.
    View in: PubMed
    Score: 0.040
  46. Triiodothyroacetic Acid Cross-Reacts With Measurement of Triiodothyronine (T3) on Various Immunoassay Platforms. Am J Clin Pathol. 2022 02 03; 157(2):156-158.
    View in: PubMed
    Score: 0.039
  47. Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J Clin Invest. 2002 Feb; 109(4):469-73.
    View in: PubMed
    Score: 0.039
  48. Modulation of thyroglobulin messenger RNA accumulation in the rat thyroid. Endocrinology. 1981 Nov; 109(5):1650-6.
    View in: PubMed
    Score: 0.038
  49. Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci U S A. 2000 Nov 21; 97(24):13209-14.
    View in: PubMed
    Score: 0.036
  50. Postirradiation screening for thyroid nodules. JAMA. 1980 Mar 21; 243(11):1131-2.
    View in: PubMed
    Score: 0.034
  51. Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice. Endocrinology. 1998 Dec; 139(12):4945-52.
    View in: PubMed
    Score: 0.031
  52. Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism. JCI Insight. 2018 10 18; 3(20).
    View in: PubMed
    Score: 0.031
  53. Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site. J Clin Invest. 1998 Mar 01; 101(5):1028-35.
    View in: PubMed
    Score: 0.030
  54. Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH. J Clin Endocrinol Metab. 1997 Dec; 82(12):3933-40.
    View in: PubMed
    Score: 0.029
  55. Transient iodide trapping defect in Hashimoto's thyroiditis detected by the combination of radionuclide and fluorescent scanning. Br J Radiol. 1977 Nov; 50(599):827-30.
    View in: PubMed
    Score: 0.029
  56. Thyroid dysfunction in chronic renal failure. A study of the pituitary-thyroid axis and peripheral turnover kinetics of thyroxine and triiodothyronine. J Clin Invest. 1977 Sep; 60(3):522-34.
    View in: PubMed
    Score: 0.029
  57. An Essential Physiological Role for MCT8 in Bone in Male Mice. Endocrinology. 2017 09 01; 158(9):3055-3066.
    View in: PubMed
    Score: 0.029
  58. Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia. Mol Cell Endocrinol. 2018 01 15; 460:24-35.
    View in: PubMed
    Score: 0.028
  59. Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases. Clin Endocrinol (Oxf). 1976 Mar; 5(2):115-25.
    View in: PubMed
    Score: 0.026
  60. Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone. Metabolism. 1972 Aug; 21(8):723-56.
    View in: PubMed
    Score: 0.020
  61. Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget. 2011 Dec; 2(12):1109-26.
    View in: PubMed
    Score: 0.019
  62. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest. 2011 Dec; 121(12):4700-11.
    View in: PubMed
    Score: 0.019
  63. Low serum free thyroxine index in ambulating elderly is due to a resetting of the threshold of thyrotropin feedback suppression. J Clin Endocrinol Metab. 1991 Oct; 73(4):843-9.
    View in: PubMed
    Score: 0.019
  64. Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1615-20.
    View in: PubMed
    Score: 0.018
  65. Neonatal detection of generalized resistance to thyroid hormone. JAMA. 1990 Nov 07; 264(17):2245-50.
    View in: PubMed
    Score: 0.018
  66. Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females. Oncogene. 2010 Oct 21; 29(42):5678-86.
    View in: PubMed
    Score: 0.018
  67. Effect of total sleep deprivation on 5'-deiodinase activity of rat brown adipose tissue. Endocrinology. 1990 Aug; 127(2):882-90.
    View in: PubMed
    Score: 0.017
  68. Inherited thyroxine-binding globulin abnormalities in man. Endocr Rev. 1989 Aug; 10(3):275-93.
    View in: PubMed
    Score: 0.016
  69. Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo. Cancer Res. 2009 Apr 15; 69(8):3689-94.
    View in: PubMed
    Score: 0.016
  70. A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol. 2008 Feb; 22(2):501-12.
    View in: PubMed
    Score: 0.014
  71. Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface. J Clin Invest. 2005 Sep; 115(9):2517-23.
    View in: PubMed
    Score: 0.012
  72. Thyrotropin controls transcription of the thyroglobulin gene. Proc Natl Acad Sci U S A. 1984 Oct; 81(19):5941-5.
    View in: PubMed
    Score: 0.012
  73. Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol. 2004 Dec; 18(12):3020-34.
    View in: PubMed
    Score: 0.012
  74. Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide. J Clin Endocrinol Metab. 2004 May; 89(5):2477-83.
    View in: PubMed
    Score: 0.011
  75. Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: a control mechanism for thyroid hormone release. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14858-63.
    View in: PubMed
    Score: 0.011
  76. Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein. Clin Endocrinol (Oxf). 2003 Oct; 59(4):500-6.
    View in: PubMed
    Score: 0.011
  77. The pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice. Hum Reprod. 2003 May; 18(5):1094-9.
    View in: PubMed
    Score: 0.011
  78. The influence of percutaneous fine needle aspiration on serum thyroglobulin. J Clin Endocrinol Metab. 1983 Jan; 56(1):26-9.
    View in: PubMed
    Score: 0.010
  79. Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3). Gen Comp Endocrinol. 2002 Jun 01; 127(1):48-58.
    View in: PubMed
    Score: 0.010
  80. Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism. J Clin Invest. 1980 Nov; 66(5):946-54.
    View in: PubMed
    Score: 0.009
  81. A novel point mutation in cluster 3 of the thyroid hormone receptor beta gene (P247L) causing mild resistance to thyroid hormone. Thyroid. 1999 Dec; 9(12):1195-203.
    View in: PubMed
    Score: 0.008
  82. Serum albumin and antibodies in the diagnosis of thyroid cancer. J Clin Endocrinol Metab. 1977 Dec; 45(6):1220-3.
    View in: PubMed
    Score: 0.007
  83. Iodination-deiodination. A radiochemical method for detection of structure and changes in structure in RNA. Biochim Biophys Acta. 1977 Mar 18; 475(2):337-51.
    View in: PubMed
    Score: 0.007
  84. Familial goitre with partial iodine organification defect, lack of thyroglobulin, and high levels of thyroid peroxidase. Clin Endocrinol (Oxf). 1977 Jan; 6(1):27-39.
    View in: PubMed
    Score: 0.007
  85. Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood. N Engl J Med. 1975 Jan 23; 292(4):171-5.
    View in: PubMed
    Score: 0.006
  86. Diagnosis and management of thyroid diseases in pregnancy. J Reprod Med. 1973 Jul; 11(1):19-22.
    View in: PubMed
    Score: 0.005
  87. Peroxidase defect in congenital goiter with complete organification block. J Clin Endocrinol Metab. 1973 Feb; 36(2):347-57.
    View in: PubMed
    Score: 0.005
  88. Diurnal rhythm in total serum thyroxine levels. Metabolism. 1971 Aug; 20(8):782-91.
    View in: PubMed
    Score: 0.005
  89. Serum tests for measurement of thyroid function. Hormones. 1971; 2(5):266-79.
    View in: PubMed
    Score: 0.005
  90. Parameters of thyroid function in maternal and cord serum at term pregnancy. J Clin Endocrinol Metab. 1969 Sep; 29(9):1276-80.
    View in: PubMed
    Score: 0.004
  91. Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone. J Clin Endocrinol Metab. 1967 Feb; 27(2):279-94.
    View in: PubMed
    Score: 0.003
  92. Coexisting thyroid and parathyroid disease--are they related? Surgery. 1983 Dec; 94(6):893-900.
    View in: PubMed
    Score: 0.003
  93. Induction of hypothyroidism and hypoprolactinemia by growth hormone producing rat pituitary tumors. Endocrinology. 1977 Jan; 100(1):216-26.
    View in: PubMed
    Score: 0.002
  94. Carcinoembryonic antigen and humoral antibody response in patients with thyroid carcinoma. Cancer Res. 1975 Oct; 35(10):2689-92.
    View in: PubMed
    Score: 0.002
  95. Differentiation of two abnormalities in thyroid peroxidase causing organification defect and goitrous hypothyroidism. Metabolism. 1975 Jan; 24(1):57-67.
    View in: PubMed
    Score: 0.001
  96. Bidirectional thyroxine exchange in pregnant sheep. Hormones. 1972; 3(4):235-49.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.