Anthony Kossiakoff to Mutation
This is a "connection" page, showing publications Anthony Kossiakoff has written about Mutation.
Connection Strength
0.872
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Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody. Sci Rep. 2017 04 03; 7(1):556.
Score: 0.254
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Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries. Biochemistry. 2004 May 25; 43(20):6076-84.
Score: 0.104
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Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM. Structure. 2019 12 03; 27(12):1862-1874.e7.
Score: 0.076
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Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J Biol Chem. 2018 02 23; 293(8):2815-2828.
Score: 0.067
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Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. J Immunol Methods. 2014 Dec 15; 415:24-30.
Score: 0.054
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Structural consequences of mutation. Curr Opin Biotechnol. 1992 Aug; 3(4):333-7.
Score: 0.046
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Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat Struct Mol Biol. 2011 Apr; 18(4):437-42.
Score: 0.042
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Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A. Protein Eng. 1990 Jul; 3(7):591-8.
Score: 0.040
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Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization. Protein Sci. 2003 Sep; 12(9):1960-70.
Score: 0.025
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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):952-7.
Score: 0.024
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Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones. Mol Biol Evol. 2002 Jul; 19(7):1083-92.
Score: 0.023
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Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites. J Mol Biol. 2002 Feb 15; 316(2):277-89.
Score: 0.022
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Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature. 2020 03; 579(7799):443-447.
Score: 0.019
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Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Nature. 2019 12; 576(7786):315-320.
Score: 0.019
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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science. 1992 Jan 17; 255(5042):306-12.
Score: 0.011
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Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11896-9.
Score: 0.011
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Crystal structures of subtilisin BPN' variants containing disulfide bonds and cavities: concerted structural rearrangements induced by mutagenesis. Proteins. 1990; 7(4):343-57.
Score: 0.010
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Crystal structure of full-length KcsA in its closed conformation. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6644-9.
Score: 0.009
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The crystallographically determined structures of atypical strained disulfides engineered into subtilisin. J Biol Chem. 1986 Nov 25; 261(33):15480-5.
Score: 0.008
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The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity. J Mol Biol. 2003 Sep 05; 332(1):195-204.
Score: 0.006
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The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation. J Biol Chem. 1988 Jun 05; 263(16):7895-906.
Score: 0.002