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Connection

Anthony Kossiakoff to Protein Engineering

This is a "connection" page, showing publications Anthony Kossiakoff has written about Protein Engineering.
Connection Strength

3.259
  1. An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability. Protein Sci. 2020 01; 29(1):141-156.
    View in: PubMed
    Score: 0.635
  2. Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin. J Mol Biol. 2015 Jul 31; 427(15):2532-2547.
    View in: PubMed
    Score: 0.469
  3. Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat Struct Mol Biol. 2011 Apr; 18(4):437-42.
    View in: PubMed
    Score: 0.348
  4. An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11011-5.
    View in: PubMed
    Score: 0.310
  5. Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold. Protein Sci. 2008 Jul; 17(7):1175-87.
    View in: PubMed
    Score: 0.286
  6. The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry. Biochemistry. 2006 Jul 18; 45(28):8488-98.
    View in: PubMed
    Score: 0.253
  7. Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity. Chem Biol. 2000 Apr; 7(4):263-74.
    View in: PubMed
    Score: 0.163
  8. Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J Biol Chem. 2018 02 23; 293(8):2815-2828.
    View in: PubMed
    Score: 0.140
  9. Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol. 2018 02 02; 430(3):337-347.
    View in: PubMed
    Score: 0.139
  10. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci. 1997 Sep; 6(9):1806-24.
    View in: PubMed
    Score: 0.137
  11. A polar ring endows improved specificity to an antibody fragment. Protein Sci. 2016 07; 25(7):1290-8.
    View in: PubMed
    Score: 0.123
  12. Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. J Immunol Methods. 2014 Dec 15; 415:24-30.
    View in: PubMed
    Score: 0.112
  13. High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries. J Mol Biol. 2007 Nov 02; 373(4):924-40.
    View in: PubMed
    Score: 0.068
  14. Structure of an AMPK complex in an inactive, ATP-bound state. Science. 2021 07 23; 373(6553):413-419.
    View in: PubMed
    Score: 0.045
  15. Molecular recognition in biological systems: from activation to inhibition. Biochem Soc Trans. 1993 Aug; 21 ( Pt 3)(3):614-8.
    View in: PubMed
    Score: 0.026
  16. Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution. Biochemistry. 1991 Apr 30; 30(17):4151-9.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.