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Connection

Anthony Kossiakoff to Trypsin

This is a "connection" page, showing publications Anthony Kossiakoff has written about Trypsin.
Connection Strength

1.078
  1. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci. 1997 Sep; 6(9):1806-24.
    View in: PubMed
    Score: 0.149
  2. Hydroxyl and water molecule orientations in trypsin: comparison to molecular dynamic structures. Basic Life Sci. 1996; 64:273-87.
    View in: PubMed
    Score: 0.133
  3. A comparison of neutron diffraction and molecular dynamics structures: hydroxyl group and water molecule orientations in trypsin. J Mol Biol. 1995 Jul 21; 250(4):553-70.
    View in: PubMed
    Score: 0.129
  4. Analysis of solvent structure in proteins using neutron D2O-H2O solvent maps: pattern of primary and secondary hydration of trypsin. Proteins. 1992 Mar; 12(3):223-36.
    View in: PubMed
    Score: 0.102
  5. Hydroxyl hydrogen conformations in trypsin determined by the neutron diffraction solvent difference map method: relative importance of steric and electrostatic factors in defining hydrogen-bonding geometries. Proc Natl Acad Sci U S A. 1990 Jun; 87(12):4468-72.
    View in: PubMed
    Score: 0.090
  6. Tertiary structure is a principal determinant to protein deamidation. Science. 1988 Apr 08; 240(4849):191-4.
    View in: PubMed
    Score: 0.078
  7. Automated peak fitting procedure for processing data from an area detector and its application to the neutron structure of trypsin. Methods Enzymol. 1985; 114:530-51.
    View in: PubMed
    Score: 0.062
  8. Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin. Basic Life Sci. 1984; 27:281-304.
    View in: PubMed
    Score: 0.058
  9. The first semi-synthetic serine protease made by native chemical ligation. Protein Expr Purif. 2003 Jun; 29(2):185-92.
    View in: PubMed
    Score: 0.055
  10. Protein dynamics investigated by the neutron diffraction-hydrogen exchange technique. Nature. 1982 Apr 22; 296(5859):713-21.
    View in: PubMed
    Score: 0.051
  11. Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin. Biochemistry. 1981 Oct 27; 20(22):6462-74.
    View in: PubMed
    Score: 0.050
  12. Neutron diffraction identifies His 57 as the catalytic base in trypsin. Nature. 1980 Nov 27; 288(5789):414-6.
    View in: PubMed
    Score: 0.047
  13. Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins. 1992 Mar; 12(3):203-22.
    View in: PubMed
    Score: 0.025
  14. A method of solvent structure analysis for proteins using D2O-H2O neutron difference maps. Methods Enzymol. 1986; 127:329-42.
    View in: PubMed
    Score: 0.017
  15. The application of neutron crystallography to the study of dynamic and and hydration properties of proteins. Annu Rev Biochem. 1985; 54:1195-227.
    View in: PubMed
    Score: 0.015
  16. Structure of bovine trypsinogen at 1.9 A resolution. Biochemistry. 1977 Feb 22; 16(4):654-64.
    View in: PubMed
    Score: 0.009
  17. Mechanisms of zymogen activation. Annu Rev Biophys Bioeng. 1977; 6:177-93.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.