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Connection

Christopher Froelich to Caspases

This is a "connection" page, showing publications Christopher Froelich has written about Caspases.
Connection Strength

0.849
  1. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J Cell Biol. 2003 Mar 17; 160(6):875-85.
    View in: PubMed
    Score: 0.212
  2. Granule-mediated killing: pathways for granzyme B-initiated apoptosis. J Exp Med. 1997 Oct 20; 186(8):1323-31.
    View in: PubMed
    Score: 0.146
  3. Granzyme B-mediated apoptosis--the elephant and the blind men? Cell Death Differ. 2004 Apr; 11(4):369-71.
    View in: PubMed
    Score: 0.057
  4. Reconstitution of caspase-3 confers low glucose-enhanced tumor necrosis factor-related apoptosis-inducing ligand cytotoxicity and Akt cleavage. Clin Cancer Res. 2004 Mar 15; 10(6):1894-900.
    View in: PubMed
    Score: 0.057
  5. Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis. Cancer Res. 2001 Jan 01; 61(1):348-54.
    View in: PubMed
    Score: 0.045
  6. Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo. J Immunol. 1999 May 01; 162(9):5345-50.
    View in: PubMed
    Score: 0.040
  7. Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7. J Biol Chem. 1998 Dec 18; 273(51):34278-83.
    View in: PubMed
    Score: 0.039
  8. Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem. 1998 Oct 16; 273(42):27084-90.
    View in: PubMed
    Score: 0.039
  9. FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation. J Immunol. 1998 Oct 15; 161(8):3936-42.
    View in: PubMed
    Score: 0.039
  10. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J Biol Chem. 1996 Jul 12; 271(28):16720-4.
    View in: PubMed
    Score: 0.033
  11. Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3. Curr Biol. 1996 Jul 01; 6(7):897-9.
    View in: PubMed
    Score: 0.033
  12. Granzyme A is a proinflammatory protease. Blood. 2009 Oct 29; 114(18):3968; author reply 3969-70.
    View in: PubMed
    Score: 0.021
  13. Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. PLoS One. 2008 Sep 01; 3(9):e3102.
    View in: PubMed
    Score: 0.019
  14. NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network. J Immunol. 2008 Jun 15; 180(12):8184-91.
    View in: PubMed
    Score: 0.019
  15. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events. J Biol Chem. 2004 May 21; 279(21):22020-9.
    View in: PubMed
    Score: 0.014
  16. The T cell death knell: immune-mediated tumor death in renal cell carcinoma. Clin Cancer Res. 2001 Oct; 7(10):3276-81.
    View in: PubMed
    Score: 0.012
  17. Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells. Cancer Immunol Immunother. 2001 Jun; 50(4):212-7.
    View in: PubMed
    Score: 0.012
  18. Cell death-associated translocation of plasma membrane components induced by CTL. J Immunol. 2000 May 01; 164(9):4641-8.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.