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Connection

Christopher Froelich to T-Lymphocytes, Cytotoxic

This is a "connection" page, showing publications Christopher Froelich has written about T-Lymphocytes, Cytotoxic.
  1. Human and mouse granzyme A induce a proinflammatory cytokine response. Immunity. 2008 Nov 14; 29(5):720-33.
    View in: PubMed
    Score: 0.266
  2. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J Cell Biol. 2003 Mar 17; 160(6):875-85.
    View in: PubMed
    Score: 0.180
  3. Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion. J Biol Chem. 2015 Mar 13; 290(11):6868-77.
    View in: PubMed
    Score: 0.102
  4. Perforin rapidly induces plasma membrane phospholipid flip-flop. PLoS One. 2011; 6(9):e24286.
    View in: PubMed
    Score: 0.081
  5. Mouse granzyme K has pro-inflammatory potential. Cell Death Differ. 2011 Jul; 18(7):1112-9.
    View in: PubMed
    Score: 0.078
  6. Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics. J Biol Chem. 2010 Jun 11; 285(24):18918-27.
    View in: PubMed
    Score: 0.074
  7. The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation. Microbes Infect. 2009 Apr; 11(4):452-9.
    View in: PubMed
    Score: 0.068
  8. Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes. J Immunol. 2008 Mar 15; 180(6):3766-74.
    View in: PubMed
    Score: 0.064
  9. Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells. J Immunol Methods. 2005 Jul; 302(1-2):13-25.
    View in: PubMed
    Score: 0.053
  10. Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes. Clin Cancer Res. 2004 Nov 01; 10(21):7402-12.
    View in: PubMed
    Score: 0.050
  11. SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity. Blood. 2005 Feb 01; 105(3):1153-61.
    View in: PubMed
    Score: 0.050
  12. Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism. Curr Opin Immunol. 2003 Oct; 15(5):528-32.
    View in: PubMed
    Score: 0.047
  13. A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death. J Cell Biol. 2003 Jan 20; 160(2):223-33.
    View in: PubMed
    Score: 0.045
  14. The T cell death knell: immune-mediated tumor death in renal cell carcinoma. Clin Cancer Res. 2001 Oct; 7(10):3276-81.
    View in: PubMed
    Score: 0.041
  15. Cell death-associated translocation of plasma membrane components induced by CTL. J Immunol. 2000 May 01; 164(9):4641-8.
    View in: PubMed
    Score: 0.037
  16. Purification and use of granzyme B. Methods Enzymol. 2000; 322:125-43.
    View in: PubMed
    Score: 0.036
  17. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science. 1998 Oct 02; 282(5386):121-5.
    View in: PubMed
    Score: 0.033
  18. Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis. Blood. 1998 Aug 01; 92(3):1044-54.
    View in: PubMed
    Score: 0.033
  19. Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo. J Immunol. 1998 Apr 01; 160(7):3610-6.
    View in: PubMed
    Score: 0.032
  20. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J Biol Chem. 1996 Jul 12; 271(28):16720-4.
    View in: PubMed
    Score: 0.028
  21. Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3. Curr Biol. 1996 Jul 01; 6(7):897-9.
    View in: PubMed
    Score: 0.028
  22. Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes. J Immunol. 1993 Dec 15; 151(12):7161-71.
    View in: PubMed
    Score: 0.024
  23. A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells. J Biol Chem. 2005 May 27; 280(21):20752-61.
    View in: PubMed
    Score: 0.013
  24. A distinct pathway of cell-mediated apoptosis initiated by granulysin. J Immunol. 2001 Jul 01; 167(1):350-6.
    View in: PubMed
    Score: 0.010
  25. Nuclear targeting of the serine protease granzyme A (fragmentin-1). J Cell Sci. 1998 Sep; 111 ( Pt 17):2645-54.
    View in: PubMed
    Score: 0.008
  26. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase. J Med Chem. 1998 Jun 18; 41(13):2289-301.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.