Christopher Froelich to Pore Forming Cytotoxic Proteins
This is a "connection" page, showing publications Christopher Froelich has written about Pore Forming Cytotoxic Proteins.
Connection Strength
0.826
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Membrane pore formation at protein-lipid interfaces. Trends Biochem Sci. 2014 Nov; 39(11):510-6.
Score: 0.122
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Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH. Mol Immunol. 2010 Sep; 47(15):2492-504.
Score: 0.090
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Detection of functional cell surface perforin by flow cytometry. J Immunol Methods. 2005 Apr; 299(1-2):117-27.
Score: 0.063
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Human neutrophils lack granzyme A, granzyme B, and perforin. Blood. 2004 Aug 01; 104(3):905-6; author reply 907-8.
Score: 0.060
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Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism. Curr Opin Immunol. 2003 Oct; 15(5):528-32.
Score: 0.057
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Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation. Immunity. 2002 Mar; 16(3):417-28.
Score: 0.051
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Flow cytometry cannot assess surface binding of perforin to target cells. Blood. 2001 Apr 01; 97(7):2181-3.
Score: 0.048
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Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases. Immunol Today. 1998 Jan; 19(1):30-6.
Score: 0.038
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Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays. Biochem Biophys Res Commun. 1996 Dec 04; 229(1):44-9.
Score: 0.035
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Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment. Biochem Biophys Res Commun. 1996 Oct 23; 227(3):658-65.
Score: 0.035
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Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion. J Biol Chem. 2015 Mar 13; 290(11):6868-77.
Score: 0.031
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Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells. J Immunol Methods. 2005 Jul; 302(1-2):13-25.
Score: 0.016
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Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes. Clin Cancer Res. 2004 Nov 01; 10(21):7402-12.
Score: 0.015
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The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins. J Virol. 2003 Apr; 77(8):4539-45.
Score: 0.014
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A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death. J Cell Biol. 2003 Jan 20; 160(2):223-33.
Score: 0.013
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Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway. J Leukoc Biol. 2002 Oct; 72(4):668-76.
Score: 0.013
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The T cell death knell: immune-mediated tumor death in renal cell carcinoma. Clin Cancer Res. 2001 Oct; 7(10):3276-81.
Score: 0.012
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Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells. Cancer Immunol Immunother. 2001 Jun; 50(4):212-7.
Score: 0.012
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P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins. J Biol Chem. 2001 May 18; 276(20):16667-73.
Score: 0.012
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Purification and use of granzyme B. Methods Enzymol. 2000; 322:125-43.
Score: 0.011
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Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin. Mol Cell Biol. 1999 Dec; 19(12):8604-15.
Score: 0.011
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BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis. J Biol Chem. 1999 Feb 12; 274(7):3953-61.
Score: 0.010
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FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation. J Immunol. 1998 Oct 15; 161(8):3936-42.
Score: 0.010
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An antimicrobial activity of cytolytic T cells mediated by granulysin. Science. 1998 Oct 02; 282(5386):121-5.
Score: 0.010
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Nuclear targeting of the serine protease granzyme A (fragmentin-1). J Cell Sci. 1998 Sep; 111 ( Pt 17):2645-54.
Score: 0.010
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Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis. Blood. 1998 Aug 01; 92(3):1044-54.
Score: 0.010
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Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction. Cell Death Differ. 1998 Jun; 5(6):488-96.
Score: 0.010
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Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus. Cell Immunol. 1997 Aug 25; 180(1):1-9.
Score: 0.009