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Connection

Jonathan Staley to RNA Splicing

This is a "connection" page, showing publications Jonathan Staley has written about RNA Splicing.
Connection Strength

5.883
  1. Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing. Mol Cell. 2022 12 15; 82(24):4681-4699.e8.
    View in: PubMed
    Score: 0.764
  2. Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6. Genes Dev. 2019 11 01; 33(21-22):1555-1574.
    View in: PubMed
    Score: 0.613
  3. Reverse transcriptases lend a hand in splicing catalysis. Nat Struct Mol Biol. 2016 06 07; 23(6):507-9.
    View in: PubMed
    Score: 0.488
  4. Evidence for a group II intron-like catalytic triplex in the spliceosome. Nat Struct Mol Biol. 2014 May; 21(5):464-471.
    View in: PubMed
    Score: 0.421
  5. The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome. RNA. 2014 Mar; 20(3):282-94.
    View in: PubMed
    Score: 0.413
  6. Splicing fidelity: DEAD/H-box ATPases as molecular clocks. RNA Biol. 2013 Jul; 10(7):1073-9.
    View in: PubMed
    Score: 0.396
  7. Staying on message: ensuring fidelity in pre-mRNA splicing. Trends Biochem Sci. 2012 Jul; 37(7):263-73.
    View in: PubMed
    Score: 0.367
  8. The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing. Mol Cell. 2010 Aug 13; 39(3):385-95.
    View in: PubMed
    Score: 0.326
  9. Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps. RNA. 2009 Jul; 15(7):1386-97.
    View in: PubMed
    Score: 0.299
  10. U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes Dev. 2007 Apr 01; 21(7):821-34.
    View in: PubMed
    Score: 0.258
  11. The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol. 2006 Jan; 26(2):513-22.
    View in: PubMed
    Score: 0.237
  12. The debranching enzyme Dbr1 regulates lariat turnover and intron splicing. Nat Commun. 2024 May 30; 15(1):4617.
    View in: PubMed
    Score: 0.212
  13. Hanging on to the branch. Nat Struct Biol. 2002 Jan; 9(1):5-7.
    View in: PubMed
    Score: 0.179
  14. An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p. Mol Cell. 1999 Jan; 3(1):55-64.
    View in: PubMed
    Score: 0.146
  15. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell. 1998 Feb 06; 92(3):315-26.
    View in: PubMed
    Score: 0.137
  16. Sequencing of lariat termini in S. cerevisiae reveals 5' splice sites, branch points, and novel splicing events. RNA. 2016 Feb; 22(2):237-53.
    View in: PubMed
    Score: 0.118
  17. RNA catalyses nuclear pre-mRNA splicing. Nature. 2013 Nov 14; 503(7475):229-34.
    View in: PubMed
    Score: 0.102
  18. Spliceosome discards intermediates via the DEAH box ATPase Prp43p. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10020-5.
    View in: PubMed
    Score: 0.080
  19. The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell. 2006 Aug 04; 23(3):389-99.
    View in: PubMed
    Score: 0.062
  20. Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nat Struct Mol Biol. 2006 Jun; 13(6):482-90.
    View in: PubMed
    Score: 0.061
  21. Multiple functions for the invariant AGC triad of U6 snRNA. RNA. 2004 Jun; 10(6):921-8.
    View in: PubMed
    Score: 0.053
  22. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor. Mol Cell. 2001 Jan; 7(1):227-32.
    View in: PubMed
    Score: 0.042
  23. Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis. J Org Chem. 2014 Apr 18; 79(8):3647-52.
    View in: PubMed
    Score: 0.026
  24. Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast. Genes Dev. 2013 Mar 15; 27(6):627-38.
    View in: PubMed
    Score: 0.024
  25. Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae. RNA. 2012 Jun; 18(6):1142-53.
    View in: PubMed
    Score: 0.023
  26. Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. Am J Hum Genet. 2009 Nov; 85(5):617-27.
    View in: PubMed
    Score: 0.019
  27. A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol. 2008 May; 15(5):444-51.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.