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Connection

Jonathan Pritchard to Gene Expression Regulation

This is a "connection" page, showing publications Jonathan Pritchard has written about Gene Expression Regulation.
  1. Gene regulatory network structure informs the distribution of perturbation effects. PLoS Comput Biol. 2025 Sep; 21(9):e1013387.
    View in: PubMed
    Score: 0.512
  2. Trans Effects on Gene Expression Can Drive Omnigenic Inheritance. Cell. 2019 05 02; 177(4):1022-1034.e6.
    View in: PubMed
    Score: 0.330
  3. Post-translational buffering leads to convergent protein expression levels between primates. Genome Biol. 2018 06 27; 19(1):83.
    View in: PubMed
    Score: 0.311
  4. Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals. Science. 2016 May 20; 352(6288):1009-13.
    View in: PubMed
    Score: 0.269
  5. RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4.
    View in: PubMed
    Score: 0.268
  6. Identification of genetic variants that affect histone modifications in human cells. Science. 2013 Nov 08; 342(6159):747-9.
    View in: PubMed
    Score: 0.225
  7. DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
    View in: PubMed
    Score: 0.200
  8. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12(1):R10.
    View in: PubMed
    Score: 0.186
  9. Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature. 2010 Apr 01; 464(7289):768-72.
    View in: PubMed
    Score: 0.175
  10. Gene expression levels are a target of recent natural selection in the human genome. Mol Biol Evol. 2009 Mar; 26(3):649-58.
    View in: PubMed
    Score: 0.161
  11. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 2008 Oct; 4(10):e1000214.
    View in: PubMed
    Score: 0.159
  12. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008 Aug; 24(8):408-15.
    View in: PubMed
    Score: 0.156
  13. Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 Jan; 637(8047):930-939.
    View in: PubMed
    Score: 0.122
  14. Systematic differences in discovery of genetic effects on gene expression and complex traits. Nat Genet. 2023 11; 55(11):1866-1875.
    View in: PubMed
    Score: 0.112
  15. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021 09; 53(9):1300-1310.
    View in: PubMed
    Score: 0.097
  16. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 10; 51(10):1494-1505.
    View in: PubMed
    Score: 0.085
  17. Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet. 2016 08; 48(8):919-26.
    View in: PubMed
    Score: 0.068
  18. msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding. PLoS One. 2015; 10(9):e0138030.
    View in: PubMed
    Score: 0.064
  19. The genetic and mechanistic basis for variation in gene regulation. PLoS Genet. 2015 Jan; 11(1):e1004857.
    View in: PubMed
    Score: 0.061
  20. Genomic variation. Impact of regulatory variation from RNA to protein. Science. 2015 Feb 06; 347(6222):664-7.
    View in: PubMed
    Score: 0.061
  21. Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014 Sep; 10(9):e1004663.
    View in: PubMed
    Score: 0.060
  22. The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation. BMC Genomics. 2014 Feb 01; 15:92.
    View in: PubMed
    Score: 0.057
  23. Primate transcript and protein expression levels evolve under compensatory selection pressures. Science. 2013 Nov 29; 342(6162):1100-4.
    View in: PubMed
    Score: 0.056
  24. Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PLoS One. 2012; 7(2):e30629.
    View in: PubMed
    Score: 0.050
  25. Precise modulation of transcription factor levels identifies features underlying dosage sensitivity. Nat Genet. 2023 05; 55(5):841-851.
    View in: PubMed
    Score: 0.027
  26. Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila. G3 (Bethesda). 2016 08 09; 6(8):2505-16.
    View in: PubMed
    Score: 0.017
  27. Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. PLoS Genet. 2015 May; 11(5):e1005216.
    View in: PubMed
    Score: 0.016
  28. The functional consequences of variation in transcription factor binding. PLoS Genet. 2014 Mar; 10(3):e1004226.
    View in: PubMed
    Score: 0.014
  29. Epigenetic modifications are associated with inter-species gene expression variation in primates. Genome Biol. 2014; 15(12):547.
    View in: PubMed
    Score: 0.014
  30. The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 2012; 8(10):e1003000.
    View in: PubMed
    Score: 0.013
  31. Genomics: ENCODE explained. Nature. 2012 Sep 06; 489(7414):52-5.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.