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Connection

Jonathan Pritchard to Polymorphism, Single Nucleotide

This is a "connection" page, showing publications Jonathan Pritchard has written about Polymorphism, Single Nucleotide.
  1. fastSTRUCTURE: variational inference of population structure in large SNP data sets. Genetics. 2014 Jun; 197(2):573-89.
    View in: PubMed
    Score: 0.257
  2. Gene expression levels are a target of recent natural selection in the human genome. Mol Biol Evol. 2009 Mar; 26(3):649-58.
    View in: PubMed
    Score: 0.178
  3. Systematic differences in discovery of genetic effects on gene expression and complex traits. Nat Genet. 2023 Nov; 55(11):1866-1875.
    View in: PubMed
    Score: 0.124
  4. Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits. Am J Hum Genet. 2022 07 07; 109(7):1286-1297.
    View in: PubMed
    Score: 0.113
  5. GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Elife. 2021 02 15; 10.
    View in: PubMed
    Score: 0.103
  6. A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. Cell Metab. 2021 03 02; 33(3):615-628.e13.
    View in: PubMed
    Score: 0.103
  7. An Expanded View of Complex Traits: From Polygenic to Omnigenic. Cell. 2017 Jun 15; 169(7):1177-1186.
    View in: PubMed
    Score: 0.080
  8. RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4.
    View in: PubMed
    Score: 0.074
  9. Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet. 2012; 8(11):e1002967.
    View in: PubMed
    Score: 0.058
  10. DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
    View in: PubMed
    Score: 0.055
  11. Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012 Jan 31; 13(1):R7.
    View in: PubMed
    Score: 0.055
  12. Adaptations to climate-mediated selective pressures in humans. PLoS Genet. 2011 Apr; 7(4):e1001375.
    View in: PubMed
    Score: 0.052
  13. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12(1):R10.
    View in: PubMed
    Score: 0.051
  14. How we are evolving. Sci Am. 2010 Oct; 303(4):40-7.
    View in: PubMed
    Score: 0.050
  15. Using environmental correlations to identify loci underlying local adaptation. Genetics. 2010 Aug; 185(4):1411-23.
    View in: PubMed
    Score: 0.049
  16. Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature. 2010 Apr 01; 464(7289):768-72.
    View in: PubMed
    Score: 0.048
  17. Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data. Bioinformatics. 2009 Dec 15; 25(24):3207-12.
    View in: PubMed
    Score: 0.047
  18. The role of geography in human adaptation. PLoS Genet. 2009 Jun; 5(6):e1000500.
    View in: PubMed
    Score: 0.046
  19. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 2008 Oct; 4(10):e1000214.
    View in: PubMed
    Score: 0.044
  20. A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet. 2006 Nov; 38(11):1251-60.
    View in: PubMed
    Score: 0.038
  21. A map of recent positive selection in the human genome. PLoS Biol. 2006 Mar; 4(3):e72.
    View in: PubMed
    Score: 0.037
  22. A high-resolution survey of deletion polymorphism in the human genome. Nat Genet. 2006 Jan; 38(1):75-81.
    View in: PubMed
    Score: 0.036
  23. Association mapping and fine mapping with TreeLD. Bioinformatics. 2005 Jul 15; 21(14):3168-70.
    View in: PubMed
    Score: 0.035
  24. Coalescent-based association mapping and fine mapping of complex trait loci. Genetics. 2005 Feb; 169(2):1071-92.
    View in: PubMed
    Score: 0.033
  25. Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet. 2004 Nov; 75(5):771-89.
    View in: PubMed
    Score: 0.033
  26. Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation. Elife. 2022 09 08; 11.
    View in: PubMed
    Score: 0.029
  27. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021 09; 53(9):1300-1310.
    View in: PubMed
    Score: 0.027
  28. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet. 2021 02; 53(2):185-194.
    View in: PubMed
    Score: 0.026
  29. Association mapping in structured populations. Am J Hum Genet. 2000 Jul; 67(1):170-81.
    View in: PubMed
    Score: 0.025
  30. Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 2020 01 30; 9.
    View in: PubMed
    Score: 0.024
  31. Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet. 2016 08; 48(8):919-26.
    View in: PubMed
    Score: 0.019
  32. Abundant contribution of short tandem repeats to gene expression variation in humans. Nat Genet. 2016 Jan; 48(1):22-9.
    View in: PubMed
    Score: 0.018
  33. The genetic and mechanistic basis for variation in gene regulation. PLoS Genet. 2015 Jan; 11(1):e1004857.
    View in: PubMed
    Score: 0.017
  34. Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014 Sep; 10(9):e1004663.
    View in: PubMed
    Score: 0.017
  35. The deleterious mutation load is insensitive to recent population history. Nat Genet. 2014 Mar; 46(3):220-4.
    View in: PubMed
    Score: 0.016
  36. The genetic architecture of adaptations to high altitude in Ethiopia. PLoS Genet. 2012; 8(12):e1003110.
    View in: PubMed
    Score: 0.015
  37. A systematic survey of loss-of-function variants in human protein-coding genes. Science. 2012 Feb 17; 335(6070):823-8.
    View in: PubMed
    Score: 0.014
  38. Haplotype variation and genotype imputation in African populations. Genet Epidemiol. 2011 Dec; 35(8):766-80.
    View in: PubMed
    Score: 0.014
  39. An approximate likelihood for genetic data under a model with recombination and population splitting. Theor Popul Biol. 2009 Jun; 75(4):331-45.
    View in: PubMed
    Score: 0.011
  40. Haplotypic background of a private allele at high frequency in the Americas. Mol Biol Evol. 2009 May; 26(5):995-1016.
    View in: PubMed
    Score: 0.011
  41. Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet. 2008 Feb; 4(2):e32.
    View in: PubMed
    Score: 0.010
  42. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science. 2008 Mar 07; 319(5868):1395-8.
    View in: PubMed
    Score: 0.010
  43. Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India. Ann Hum Genet. 2008 Jul; 72(Pt 4):535-46.
    View in: PubMed
    Score: 0.010
  44. Completing the map of human genetic variation. Nature. 2007 May 10; 447(7141):161-5.
    View in: PubMed
    Score: 0.010
  45. Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet. 2007 Jan; 39(1):31-40.
    View in: PubMed
    Score: 0.010
  46. The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium. Genetics. 2006 Mar; 172(3):2001-5.
    View in: PubMed
    Score: 0.009
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.