Jonathan Pritchard to Quantitative Trait Loci
This is a "connection" page, showing publications Jonathan Pritchard has written about Quantitative Trait Loci.
Connection Strength
4.979
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Genetic variation in MHC proteins is associated with T cell receptor expression biases. Nat Genet. 2016 09; 48(9):995-1002.
Score: 0.431
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RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4.
Score: 0.424
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WASP: allele-specific software for robust molecular quantitative trait locus discovery. Nat Methods. 2015 Nov; 12(11):1061-3.
Score: 0.406
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Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PLoS One. 2012; 7(2):e30629.
Score: 0.317
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DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
Score: 0.316
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Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012 Jan 31; 13(1):R7.
Score: 0.316
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High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 2008 Oct; 4(10):e1000214.
Score: 0.251
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Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008 Aug; 24(8):408-15.
Score: 0.246
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Systematic differences in discovery of genetic effects on gene expression and complex traits. Nat Genet. 2023 Nov; 55(11):1866-1875.
Score: 0.178
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A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice. Genome Res. 2023 May; 33(5):689-702.
Score: 0.172
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A natural mutator allele shapes mutation spectrum variation in mice. Nature. 2022 05; 605(7910):497-502.
Score: 0.161
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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021 09; 53(9):1300-1310.
Score: 0.153
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GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Elife. 2021 02 15; 10.
Score: 0.148
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Trans Effects on Gene Expression Can Drive Omnigenic Inheritance. Cell. 2019 05 02; 177(4):1022-1034.e6.
Score: 0.130
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Evidence for Weak Selective Constraint on Human Gene Expression. Genetics. 2019 02; 211(2):757-772.
Score: 0.127
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Annotation-free quantification of RNA splicing using LeafCutter. Nat Genet. 2018 01; 50(1):151-158.
Score: 0.118
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Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. Am J Hum Genet. 2017 Nov 02; 101(5):686-699.
Score: 0.117
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Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet. 2016 08; 48(8):919-26.
Score: 0.107
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The genetic and mechanistic basis for variation in gene regulation. PLoS Genet. 2015 Jan; 11(1):e1004857.
Score: 0.097
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Genomic variation. Impact of regulatory variation from RNA to protein. Science. 2015 Feb 06; 347(6222):664-7.
Score: 0.096
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Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014 Sep; 10(9):e1004663.
Score: 0.095
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Identification of genetic variants that affect histone modifications in human cells. Science. 2013 Nov 08; 342(6159):747-9.
Score: 0.089
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A statistical framework for joint eQTL analysis in multiple tissues. PLoS Genet. 2013 May; 9(5):e1003486.
Score: 0.086
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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 2012; 8(10):e1003000.
Score: 0.083
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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12(1):R10.
Score: 0.073
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Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature. 2010 Apr 01; 464(7289):768-72.
Score: 0.069
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Association mapping and fine mapping with TreeLD. Bioinformatics. 2005 Jul 15; 21(14):3168-70.
Score: 0.049
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RNA editing underlies genetic risk of common inflammatory diseases. Nature. 2022 08; 608(7923):569-577.
Score: 0.041
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Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes. Elife. 2018 05 08; 7.
Score: 0.030
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Abundant contribution of short tandem repeats to gene expression variation in humans. Nat Genet. 2016 Jan; 48(1):22-9.
Score: 0.026
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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions. Cell. 2015 Aug 27; 162(5):1051-65.
Score: 0.025