Alain Labro to Mutation
This is a "connection" page, showing publications Alain Labro has written about Mutation.
Connection Strength
0.359
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The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. J Mol Cell Cardiol. 2010 Jun; 48(6):1096-104.
Score: 0.135
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Inverted allosteric coupling between activation and inactivation gates in K+ channels. Proc Natl Acad Sci U S A. 2018 05 22; 115(21):5426-5431.
Score: 0.061
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Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel. Biophys J. 2014 Jan 07; 106(1):134-44.
Score: 0.045
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The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J Biol Chem. 2011 Jan 07; 286(1):717-25.
Score: 0.036
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A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1476-84.
Score: 0.030
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Gating of shaker-type channels requires the flexibility of S6 caused by prolines. J Biol Chem. 2003 Dec 12; 278(50):50724-31.
Score: 0.022
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Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening. Sci Rep. 2015 Nov 30; 5:17402.
Score: 0.013
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KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. J Biol Chem. 2011 Jan 07; 286(1):707-16.
Score: 0.009
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Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. Biophys J. 2006 Dec 15; 91(12):4381-91.
Score: 0.007