Alain Labro to Humans
This is a "connection" page, showing publications Alain Labro has written about Humans.
Connection Strength
0.207
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The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells. Channels (Austin). 2021 Dec; 15(1):239-252.
Score: 0.023
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Inverted allosteric coupling between activation and inactivation gates in K+ channels. Proc Natl Acad Sci U S A. 2018 05 22; 115(21):5426-5431.
Score: 0.018
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Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization. Nat Commun. 2015 Dec 17; 6:10173.
Score: 0.015
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Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel. Biophys J. 2014 Jan 07; 106(1):134-44.
Score: 0.013
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Molecular mechanism for depolarization-induced modulation of Kv channel closure. J Gen Physiol. 2012 Nov; 140(5):481-93.
Score: 0.012
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The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J Biol Chem. 2011 Jan 07; 286(1):717-25.
Score: 0.011
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The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. J Mol Cell Cardiol. 2010 Jun; 48(6):1096-104.
Score: 0.010
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Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues. J Gen Physiol. 2008 Dec; 132(6):667-80.
Score: 0.009
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A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1476-84.
Score: 0.009
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Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels. J Gen Physiol. 2005 Jan; 125(1):71-80.
Score: 0.007
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Gating of shaker-type channels requires the flexibility of S6 caused by prolines. J Biol Chem. 2003 Dec 12; 278(50):50724-31.
Score: 0.007
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Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population. Orphanet J Rare Dis. 2023 01 31; 18(1):23.
Score: 0.006
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Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes. Biol Open. 2022 02 15; 11(2).
Score: 0.006
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Constitutive, Basal, and ß-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-?B Signaling. Int J Mol Sci. 2021 Dec 09; 22(24).
Score: 0.006
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Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae. Int J Mol Sci. 2021 Nov 24; 22(23).
Score: 0.006
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Molecular autopsy and subsequent functional analysis reveal de novo DSG2 mutation as cause of sudden death. Eur J Med Genet. 2021 Nov; 64(11):104322.
Score: 0.006
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Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient. Cardiovasc Res. 2021 07 07; 117(8):1923-1934.
Score: 0.006
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iPSC-Cardiomyocyte Models of Brugada Syndrome-Achievements, Challenges and Future Perspectives. Int J Mol Sci. 2021 Mar 10; 22(6).
Score: 0.006
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Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9365-9376.
Score: 0.005
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Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening. Sci Rep. 2015 Nov 30; 5:17402.
Score: 0.004
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Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation. PLoS One. 2015; 10(10):e0141349.
Score: 0.004
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Quantitative single-cell ion-channel gene expression profiling through an improved qRT-PCR technique combined with whole cell patch clamp. J Neurosci Methods. 2012 Jul 30; 209(1):227-34.
Score: 0.003
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The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels. PLoS One. 2012; 7(5):e37143.
Score: 0.003
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Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1. Eur Biophys J. 2011 Jun; 40(6):783-93.
Score: 0.003
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Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.
Score: 0.003
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Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels. J Biol Chem. 2009 Nov 13; 284(46):31625-34.
Score: 0.002
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Role of the S6 C-terminus in KCNQ1 channel gating. J Physiol. 2007 Dec 01; 585(Pt 2):325-37.
Score: 0.002
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Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. Biophys J. 2006 Dec 15; 91(12):4381-91.
Score: 0.002