Alain Labro to KCNQ1 Potassium Channel
This is a "connection" page, showing publications Alain Labro has written about KCNQ1 Potassium Channel.
Connection Strength
2.014
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Evaluating the proarrhythmic risk of delayed-action compounds in serum free cell culture conditions; serum-starvation accelerates/amplifies the effect of probucol on the KCNQ1 + KCNE1 channel. J Pharmacol Toxicol Methods. 2024 Nov-Dec; 130:107566.
Score: 0.870
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The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J Biol Chem. 2011 Jan 07; 286(1):717-25.
Score: 0.332
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The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. J Mol Cell Cardiol. 2010 Jun; 48(6):1096-104.
Score: 0.310
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Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population. Orphanet J Rare Dis. 2023 01 31; 18(1):23.
Score: 0.194
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Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channels. J Biol Chem. 2012 Oct 19; 287(43):36158-67.
Score: 0.094
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KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. J Biol Chem. 2011 Jan 07; 286(1):707-16.
Score: 0.083
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Role of the S6 C-terminus in KCNQ1 channel gating. J Physiol. 2007 Dec 01; 585(Pt 2):325-37.
Score: 0.067
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Molecular autopsy and subsequent functional analysis reveal de novo DSG2 mutation as cause of sudden death. Eur J Med Genet. 2021 Nov; 64(11):104322.
Score: 0.044
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Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.
Score: 0.020