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Carole Ober to Asthma

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This is a "connection" page, showing publications Carole Ober has written about Asthma.
Carole Ober
Connection Strength
14.138
Asthma
  1. Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children. Am J Hum Genet. 2025 Jul 03; 112(7):1610-1624.
    View in: PubMed
    Score: 0.518
  2. Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations. Genome Med. 2025 Apr 10; 17(1):35.
    View in: PubMed
    Score: 0.510
  3. Population descriptors in asthma and allergy research: Time to regroup. J Allergy Clin Immunol. 2024 Jul; 154(1):79-81.
    View in: PubMed
    Score: 0.476
  4. Screening asthmatics for atopic status using the ALergy EXplorer (ALEX2) macroarray. J Asthma. 2024 Sep; 61(9):1050-1057.
    View in: PubMed
    Score: 0.472
  5. African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Med. 2022 09 29; 14(1):112.
    View in: PubMed
    Score: 0.428
  6. DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma. Proc Natl Acad Sci U S A. 2022 06 14; 119(24):e2116467119.
    View in: PubMed
    Score: 0.418
  7. Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region. Genome Med. 2022 05 24; 14(1):55.
    View in: PubMed
    Score: 0.417
  8. A-to-I editing of miR-200b-3p in airway cells is associated with moderate-to-severe asthma. Eur Respir J. 2021 07; 58(1).
    View in: PubMed
    Score: 0.394
  9. Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study. Lancet Respir Med. 2020 05; 8(5):482-492.
    View in: PubMed
    Score: 0.362
  10. Genetic architecture of moderate-to-severe asthma mirrors that of mild asthma. J Allergy Clin Immunol. 2019 12; 144(6):1521-1523.
    View in: PubMed
    Score: 0.347
  11. Immune development and environment: lessons from Amish and Hutterite children. Curr Opin Immunol. 2017 Oct; 48:51-60.
    View in: PubMed
    Score: 0.301
  12. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. JCI Insight. 2016 12 08; 1(20):e90151.
    View in: PubMed
    Score: 0.286
  13. Leveraging gene-environment interactions and endotypes for asthma gene discovery. J Allergy Clin Immunol. 2016 Mar; 137(3):667-79.
    View in: PubMed
    Score: 0.271
  14. Asthma Genetics in the Post-GWAS Era. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S85-90.
    View in: PubMed
    Score: 0.271
  15. Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):376-85.
    View in: PubMed
    Score: 0.270
  16. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun. 2015 Jan 16; 6:5965.
    View in: PubMed
    Score: 0.251
  17. Maternal asthma and microRNA regulation of soluble HLA-G in the airway. J Allergy Clin Immunol. 2013 Jun; 131(6):1496-503.
    View in: PubMed
    Score: 0.221
  18. Maternal microchimerism protects against the development of asthma. J Allergy Clin Immunol. 2013 Jul; 132(1):39-44.
    View in: PubMed
    Score: 0.220
  19. Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet. 2012 Feb 10; 90(2):273-81.
    View in: PubMed
    Score: 0.205
  20. Rising prevalence of asthma is sex-specific in a US farming population. J Allergy Clin Immunol. 2011 Oct; 128(4):774-9.
    View in: PubMed
    Score: 0.198
  21. IFNG genotype and sex interact to influence the risk of childhood asthma. J Allergy Clin Immunol. 2011 Sep; 128(3):524-31.
    View in: PubMed
    Score: 0.197
  22. The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 2011 Jul; 242(1):10-30.
    View in: PubMed
    Score: 0.196
  23. Gene-environment interactions in human disease: nuisance or opportunity? Trends Genet. 2011 Mar; 27(3):107-15.
    View in: PubMed
    Score: 0.190
  24. Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med. 2008 Apr 17; 358(16):1682-91.
    View in: PubMed
    Score: 0.157
  25. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet. 2007 Oct; 81(4):829-34.
    View in: PubMed
    Score: 0.150
  26. Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life. J Allergy Clin Immunol. 2007 Jun; 119(6):1423-9.
    View in: PubMed
    Score: 0.148
  27. Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci. J Allergy Clin Immunol. 2006 Aug; 118(2):396-402.
    View in: PubMed
    Score: 0.138
  28. Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. Curr Allergy Asthma Rep. 2006 May; 6(3):241-6.
    View in: PubMed
    Score: 0.137
  29. Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. Respir Res. 2005 Dec 10; 6:145.
    View in: PubMed
    Score: 0.133
  30. Rethinking genetic models of asthma: the role of environmental modifiers. Curr Opin Immunol. 2005 Dec; 17(6):670-8.
    View in: PubMed
    Score: 0.132
  31. Prediction and characterization of genetically regulated expression of asthma tissues from African-ancestry populations. J Allergy Clin Immunol. 2026 Jan; 157(1):253-261.
    View in: PubMed
    Score: 0.131
  32. Genetic characterization of preschool wheeze phenotypes. J Allergy Clin Immunol. 2025 Dec; 156(6):1537-1546.
    View in: PubMed
    Score: 0.130
  33. Genetic risk for adult obstructive lung function and its early life associations. J Allergy Clin Immunol. 2025 Oct; 156(4):937-947.
    View in: PubMed
    Score: 0.130
  34. Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection. Biomolecules. 2025 Jul 22; 15(8).
    View in: PubMed
    Score: 0.130
  35. Newborn blood DNA methylation and childhood asthma: findings from the ECHO program. Int J Epidemiol. 2025 Apr 12; 54(3).
    View in: PubMed
    Score: 0.127
  36. EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma. Am J Hum Genet. 2025 May 01; 112(5):1199-1214.
    View in: PubMed
    Score: 0.127
  37. Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. Am J Respir Crit Care Med. 2005 Jul 01; 172(1):67-73.
    View in: PubMed
    Score: 0.127
  38. Early-life wheeze trajectories are associated with distinct asthma transcriptomes later in life. J Allergy Clin Immunol. 2025 Sep; 156(3):640-650.
    View in: PubMed
    Score: 0.127
  39. Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am J Hum Genet. 2005 Apr; 76(4):696-704.
    View in: PubMed
    Score: 0.126
  40. Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet. 2005 Feb; 76(2):349-57.
    View in: PubMed
    Score: 0.125
  41. Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations. Nat Commun. 2024 May 28; 15(1):4546.
    View in: PubMed
    Score: 0.120
  42. Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop. J Allergy Clin Immunol. 2024 Apr; 153(4):954-968.
    View in: PubMed
    Score: 0.117
  43. Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respir Res. 2003; 4:14.
    View in: PubMed
    Score: 0.116
  44. Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma. J Allergy Clin Immunol. 2024 Mar; 153(3):809-820.
    View in: PubMed
    Score: 0.115
  45. Atopic and non-atopic effects of fish oil supplementation during pregnancy. Thorax. 2023 12; 78(12):1168-1174.
    View in: PubMed
    Score: 0.114
  46. A conversation on allergy: recognizing the past and looking to the future. Immunol Cell Biol. 2023 Nov-Dec; 101(10):936-946.
    View in: PubMed
    Score: 0.114
  47. Revealing polygenic pleiotropy using genetic risk scores for asthma. HGG Adv. 2023 10 12; 4(4):100233.
    View in: PubMed
    Score: 0.114
  48. Asthma-protective agents in dust from traditional farm environments. J Allergy Clin Immunol. 2023 09; 152(3):610-621.
    View in: PubMed
    Score: 0.112
  49. Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. J Allergy Clin Immunol. 2003 Mar; 111(3):527-32.
    View in: PubMed
    Score: 0.110
  50. A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome. J Allergy Clin Immunol. 2023 06; 151(6):1609-1621.
    View in: PubMed
    Score: 0.110
  51. Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium. Front Cell Infect Microbiol. 2022; 12:1060748.
    View in: PubMed
    Score: 0.109
  52. Discerning asthma endotypes through comorbidity mapping. Nat Commun. 2022 11 07; 13(1):6712.
    View in: PubMed
    Score: 0.108
  53. New Insights Relating Gasdermin B to the Onset of Childhood Asthma. Am J Respir Cell Mol Biol. 2022 Oct; 67(4):430-437.
    View in: PubMed
    Score: 0.107
  54. Prenatal exposure to ambient air pollution is associated with early life immune perturbations. J Allergy Clin Immunol. 2023 01; 151(1):212-221.
    View in: PubMed
    Score: 0.106
  55. Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma. J Allergy Clin Immunol. 2022 10; 150(4):972-978.e7.
    View in: PubMed
    Score: 0.104
  56. Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. J Allergy Clin Immunol. 2022 09; 150(3):622-630.
    View in: PubMed
    Score: 0.103
  57. 17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children. Clin Exp Allergy. 2022 04; 52(4):565-568.
    View in: PubMed
    Score: 0.101
  58. Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. Nat Commun. 2021 10 21; 12(1):6115.
    View in: PubMed
    Score: 0.100
  59. Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus. Genome Med. 2021 10 10; 13(1):157.
    View in: PubMed
    Score: 0.100
  60. Multiethnic genome-wide and HLA association study of total serum IgE level. J Allergy Clin Immunol. 2021 12; 148(6):1589-1595.
    View in: PubMed
    Score: 0.099
  61. Genome-wide association study identifies TNFSF15 associated with childhood asthma. Allergy. 2022 01; 77(1):218-229.
    View in: PubMed
    Score: 0.098
  62. Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children. J Allergy Clin Immunol. 2021 12; 148(6):1505-1514.
    View in: PubMed
    Score: 0.097
  63. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection. Am J Respir Crit Care Med. 2021 04 01; 203(7):822-830.
    View in: PubMed
    Score: 0.096
  64. Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood. Am J Respir Crit Care Med. 2021 04 01; 203(7):864-870.
    View in: PubMed
    Score: 0.096
  65. Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma. J Allergy Clin Immunol. 2021 07; 148(1):128-138.
    View in: PubMed
    Score: 0.095
  66. FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun. 2020 12 16; 11(1):6398.
    View in: PubMed
    Score: 0.094
  67. Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma. Commun Biol. 2020 11 13; 3(1):678.
    View in: PubMed
    Score: 0.094
  68. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet. 2000 Nov; 67(5):1154-62.
    View in: PubMed
    Score: 0.093
  69. Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study. Eur Respir J. 2020 09; 56(3).
    View in: PubMed
    Score: 0.093
  70. Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma. Genome Med. 2020 07 20; 12(1):64.
    View in: PubMed
    Score: 0.092
  71. Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol. 2020 Jul; 146(1):203-206.e3.
    View in: PubMed
    Score: 0.090
  72. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe. 2020 04 08; 27(4):614-628.e6.
    View in: PubMed
    Score: 0.089
  73. Advances in asthma and allergic disease genetics: Is bigger always better? J Allergy Clin Immunol. 2019 12; 144(6):1495-1506.
    View in: PubMed
    Score: 0.087
  74. Associations between fungal and bacterial microbiota of airways and asthma endotypes. J Allergy Clin Immunol. 2019 11; 144(5):1214-1227.e7.
    View in: PubMed
    Score: 0.085
  75. Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. Lancet Respir Med. 2019 06; 7(6):509-522.
    View in: PubMed
    Score: 0.084
  76. A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle. J Allergy Clin Immunol. 2018 09; 142(3):749-764.e3.
    View in: PubMed
    Score: 0.077
  77. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018 01; 50(1):42-53.
    View in: PubMed
    Score: 0.077
  78. Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. N Engl J Med. 2016 Aug 04; 375(5):411-421.
    View in: PubMed
    Score: 0.070
  79. Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One. 2014; 9(8):e104396.
    View in: PubMed
    Score: 0.061
  80. Genome-wide interaction studies reveal sex-specific asthma risk alleles. Hum Mol Genet. 2014 Oct 01; 23(19):5251-9.
    View in: PubMed
    Score: 0.060
  81. Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med. 2013 Apr 11; 368(15):1398-407.
    View in: PubMed
    Score: 0.055
  82. A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol. 2013 Apr; 131(4):1176-84.
    View in: PubMed
    Score: 0.054
  83. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol. 2012 Dec; 130(6):1294-301.
    View in: PubMed
    Score: 0.054
  84. Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol. 2012 Oct; 130(4):861-8.e7.
    View in: PubMed
    Score: 0.052
  85. Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. J Allergy Clin Immunol. 2012 Sep; 130(3):622-629.e9.
    View in: PubMed
    Score: 0.052
  86. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet. 2012 May 01; 21(9):2111-23.
    View in: PubMed
    Score: 0.051
  87. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011 Jul 31; 43(9):887-92.
    View in: PubMed
    Score: 0.049
  88. Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. J Allergy Clin Immunol. 2009 Dec; 124(6):1204-9.e9.
    View in: PubMed
    Score: 0.044
  89. Sex-specific genetic architecture of human disease. Nat Rev Genet. 2008 Dec; 9(12):911-22.
    View in: PubMed
    Score: 0.041
  90. Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. J Allergy Clin Immunol. 2004 Mar; 113(3):511-8.
    View in: PubMed
    Score: 0.029
  91. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet. 2003 Sep; 73(3):612-26.
    View in: PubMed
    Score: 0.028
  92. Association of HLA-DRB1*09:01 with tIgE levels among African-ancestry individuals with asthma. J Allergy Clin Immunol. 2020 07; 146(1):147-155.
    View in: PubMed
    Score: 0.022
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.