AaronFoxAaron Fox41.78927490000000-87.601250000000001772Fox, AaronProfessorplugins:FeaturedVideosFeatured Videosprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 105903628659466Fong R, Khokhar S, Chowdhury AN, Xie KG, Wong JH, Fox AP, Xie ZJournal of neurophysiologyCaffeine accelerates recovery from general anesthesia via multiple pathways. J Neurophysiol. 2017 09 01; 118(3):1591-1597.J Neurophysiol2017-06-28T00:00:002017Caffeine accelerates recovery from general anesthesia via multiple pathways.D005089Physiology431080.951164ExocytosisD002395Chemicals & Drugs38880.956444CatecholaminesAnesthesia and Critical CareD007530Chemicals & Drugs27640.938269IsofluraneRobertFongRobert Fong0.000000000000000.000000000000002882Fong, RobertAssociate ProfessorD019439Anatomy10370.961678Chromaffin Cells12759879Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KSMetabolism: clinical and experimentalA 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism. 2003 May; 52(5):528-34.Metabolism2003-05-01T00:00:002003A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.Pharmacological and Physiological Sciences19339466Souvannakitti D, Kumar GK, Fox A, Prabhakar NRJournal of neurophysiologyNeonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells. J Neurophysiol. 2009 Jun; 101(6):2837-46.J Neurophysiol2009-04-01T00:00:002009Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells.20705601Souvannakitti D, Nanduri J, Yuan G, Kumar GK, Fox AP, Prabhakar NRThe Journal of neuroscience : the official journal of the Society for NeuroscienceNADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells. J Neurosci. 2010 Aug 11; 30(32):10763-72.J Neurosci2010-08-11T00:00:002010NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells.19515956Herring BE, Xie Z, Marks J, Fox APJournal of neurophysiologyIsoflurane inhibits the neurotransmitter release machinery. J Neurophysiol. 2009 Aug; 102(2):1265-73.J Neurophysiol2009-06-10T00:00:002009Isoflurane inhibits the neurotransmitter release machinery.21173083Herring BE, McMillan K, Pike CM, Marks J, Fox AP, Xie ZThe Journal of physiologyEtomidate and propofol inhibit the neurotransmitter release machinery at different sites. J Physiol. 2011 Mar 01; 589(Pt 5):1103-15.J Physiol2010-12-20T00:00:002010Etomidate and propofol inhibit the neurotransmitter release machinery at different sites.19536498Souvannakitti D, Kumar GK, Fox A, Prabhakar NRAdvances in experimental medicine and biologyContrasting effects of intermittent and continuous hypoxia on low O(2) evoked catecholamine secretion from neonatal rat chromaffin cells. Adv Exp Med Biol. 2009; 648:345-9.Adv Exp Med Biol2009-01-01T00:00:002009Contrasting effects of intermittent and continuous hypoxia on low O(2) evoked catecholamine secretion from neonatal rat chromaffin cells.22232674Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NRProceedings of the National Academy of Sciences of the United States of AmericaEpigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2515-20.Proc Natl Acad Sci U S A2012-01-09T00:00:002012Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.D050825Chemicals & Drugs10140.987737Synaptosomal-Associated Protein 2522744006Makarenko VV, Nanduri J, Raghuraman G, Fox AP, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NRAmerican journal of physiology. Cell physiologyEndogenous H2S is required for hypoxic sensing by carotid body glomus cells. Am J Physiol Cell Physiol. 2012 Nov 01; 303(9):C916-23.Am J Physiol Cell Physiol2012-06-27T00:00:002012Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.20664070Souvannakitti D, Kuri B, Yuan G, Pawar A, Kumar GK, Smith C, Fox AP, Prabhakar NRAmerican journal of physiology. Cell physiologyNeonatal intermittent hypoxia impairs neuronal nicotinic receptor expression and function in adrenal chromaffin cells. Am J Physiol Cell Physiol. 2010 Aug; 299(2):C381-8.Am J Physiol Cell Physiol2010-08-01T00:00:002010Neonatal intermittent hypoxia impairs neuronal nicotinic receptor expression and function in adrenal chromaffin cells.25377087Makarenko VV, Peng YJ, Yuan G, Fox AP, Kumar GK, Nanduri J, Prabhakar NRAmerican journal of physiology. Cell physiologyCaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C146-54.Am J Physiol Cell Physiol2014-11-05T00:00:002014CaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body.https://exosomes.uchicago.eduExosome websitehttps://neurology.uchicago.edu/faculty/jeremy-marks-md-phdDepartment of Neurologyhttps://www.uchicagomedicine.org/find-a-physician/physician/jeremy-d-marksUniversity of Chicago Hospitalshttp://nelsonlab.uchicago.edu Nelson Lab Websitehttps://integrativephysiology.uchicago.edu/Institute for Integrative Physiology and Center for Systems Biology of Oxygen Sensing2004-08-31NIHFOX, AARON P.2002-09-20Nicotine Addiction: ACh Receptors and SecretionR01DA0135132003-02-28NIHFOX, AARON P.1997-03-01SYNAPTIC PHYSIOLOGYP01NS0338262013-04-30NIHFOX, AARON P.2008-07-01Isoflurane: Identification of Key New TargetsR01GM0818092005-08-31NIHFOX, AARON P.1988-04-01STUDIES OF N-TYPE CALCIUM CHANNELSR01NS0261891999-08-31NIHFOX, AARON P.1991-04-01CHROMAFFIN CELLS--STIMULUS SECRETION COUPLINGR01GM0435602021-07-31NIHFOX, AARON P.2015-09-20Reversing anesthesia with CaffeineR01GM1161191994-03-31NIHFOX, AARON P.1988-04-01HIPPOCAMPAL CALCIUM CHANNELS--PHARMACOLOGY AND FUNCTIONR29NS026189Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorMedicineUniversity of ChicagoVytautasBindokasVytautas Bindokas41.78927490000000-87.601250000000001571Bindokas, VytautasResearch Associate ProfessorNanduri R.Prabhakar2WNnD7QHEMzMknJtY0fp/Cv/+94=Nanduri R. Prabhakar41.78927490000000-87.601250000000001680Prabhakar, Nanduri R.Professor1.833750.00928187167research areas0.9228790.014670914coauthor of49.59422.2492460similar to1124selected publicationsYing-JiePengYing-Jie Peng41.78927490000000-87.601250000000002150Peng, Ying-JieResearch ProfessorEric A.SchwartzEric A. Schwartz41.78927490000000-87.601250000000002156Schwartz, Eric A.ProfessorJayasriNanduriJayasri Nanduri41.78927490000000-87.601250000000002544Nanduri, JayasriResearch ProfessorStephenArcherStephen Archer41.78927490000000-87.601250000000002615Archer, StephenProfessorDeborahNelson2WdlGK4bOfnamXNnYUHhvWD+6g==Deborah Nelson41.78927490000000-87.60125000000000271Nelson, DeborahProfessorZhengXieZheng Xie41.78927490000000-87.6012500000000057Xie, ZhengProfessorVladimirRiazanskiVladimir Riazanski41.78927490000000-87.60125000000000572Riazanski, VladimirResearch Associate ProfessorJeremyMarksJeremy Marks41.78927490000000-87.60125000000000708Marks, JeremyAssociate ProfessorMitchel L.Villereal2m5/Aq0ZHP75hHlsaUXv9Gq0+s+oMitchel L. Villereal41.78927490000000-87.60125000000000766Villereal, Mitchel L.Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Research ProfessorResearch Professortrue1Research ProfessorResearch Professortrue1Associate ProfessorAssociate Professortrue1Research Associate ProfessorResearch Associate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Research Associate ProfessorResearch Associate Professortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 694484Authorship 690397Authorship 726794Authorship 72732118021320Fox AP, Cahill AL, Currie KP, Grabner C, Harkins AB, Herring B, Hurley JH, Xie ZActa physiologica (Oxford, England)N- and P/Q-type Ca2+ channels in adrenal chromaffin cells. Acta Physiol (Oxf). 2008 Feb; 192(2):247-61.Acta Physiol (Oxf)2007-11-16T00:00:002007N- and P/Q-type Ca2+ channels in adrenal chromaffin cells.24375022Wang Q, Fong R, Mason P, Fox AP, Xie ZJournal of neurophysiologyCaffeine accelerates recovery from general anesthesia. J Neurophysiol. 2014 Mar; 111(6):1331-40.J Neurophysiol2013-12-26T00:00:002013Caffeine accelerates recovery from general anesthesia.Medicine-Emergency MedicinePediatrics-NeonatologyChicago60637ILAuthorship 856543Authorship 857327Authorship 85710326561606Makarenko VV, Ahmmed GU, Peng YJ, Khan SA, Nanduri J, Kumar GK, Fox AP, Prabhakar NRJournal of neurophysiologyCaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia. J Neurophysiol. 2016 Jan 01; 115(1):345-54.J Neurophysiol2015-11-11T00:00:002015CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia.Authorship 558704Authorship 543736Authorship 542543Authorship 544082Authorship 589645Authorship 5479412Authorship 548655Authorship 5967612Authorship 543462Authorship 580744Authorship 587127Authorship 587425Authorship 548722Authorship 562013Authorship 564195Authorship 60036411923406Pan CY, Jeromin A, Lundstrom K, Yoo SH, Roder J, Fox APThe Journal of neuroscience : the official journal of the Society for NeuroscienceAlterations in exocytosis induced by neuronal Ca2+ sensor-1 in bovine chromaffin cells. J Neurosci. 2002 Apr 01; 22(7):2427-33.J Neurosci2002-04-01T00:00:002002Alterations in exocytosis induced by neuronal Ca2+ sensor-1 in bovine chromaffin cells.12879981Harkins AB, Fox APCerebellum (London, England)Cell death in weaver mouse cerebellum. Cerebellum. 2002 Jul; 1(3):201-6.Cerebellum2002-07-01T00:00:002002Cell death in weaver mouse cerebellum.11986363Currie KP, Fox APThe Journal of physiologyCause for excite-M-ent in adrenal chromaffin cells. J Physiol. 2002 May 01; 540(Pt 3):729.J Physiol2002-05-01T00:00:002002Cause for excite-M-ent in adrenal chromaffin cells.11738479Pan CY, Kao YH, Fox APNeurochemistry internationalEnhancement of inward Ca(2+) currents in bovine chromaffin cells by green tea polyphenol extracts. Neurochem Int. 2002 Feb; 40(2):131-7.Neurochem Int2002-02-01T00:00:002002Enhancement of inward Ca(2+) currents in bovine chromaffin cells by green tea polyphenol extracts.15944233Grabner CP, Price SD, Lysakowski A, Fox APJournal of neurophysiologyMouse chromaffin cells have two populations of dense core vesicles. J Neurophysiol. 2005 Sep; 94(3):2093-104.J Neurophysiol2005-06-08T00:00:002005Mouse chromaffin cells have two populations of dense core vesicles.12867528Harkins AB, Cahill AL, Powers JF, Tischler AS, Fox APJournal of neurophysiologyExpression of recombinant calcium channels support secretion in a mouse pheochromocytoma cell line. J Neurophysiol. 2003 Oct; 90(4):2325-33.J Neurophysiol2003-07-16T00:00:002003Expression of recombinant calcium channels support secretion in a mouse pheochromocytoma cell line.23136341Xie Z, McMillan K, Pike CM, Cahill AL, Herring BE, Wang Q, Fox APJournal of neurophysiologyInteraction of anesthetics with neurotransmitter release machinery proteins. J Neurophysiol. 2013 Feb; 109(3):758-67.J Neurophysiol2012-11-07T00:00:002012Interaction of anesthetics with neurotransmitter release machinery proteins.16445859Cahill AL, Herring BE, Fox APBMC neuroscienceStable silencing of SNAP-25 in PC12 cells by RNA interference. BMC Neurosci. 2006 Jan 30; 7:9.BMC Neurosci2006-01-30T00:00:002006Stable silencing of SNAP-25 in PC12 cells by RNA interference.16788073Grabner CP, Price SD, Lysakowski A, Cahill AL, Fox APProceedings of the National Academy of Sciences of the United States of AmericaRegulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):10035-40.Proc Natl Acad Sci U S A2006-06-20T00:00:002006Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3.11882675Currie KP, Fox APThe Journal of physiologyDifferential facilitation of N- and P/Q-type calcium channels during trains of action potential-like waveforms. J Physiol. 2002 Mar 01; 539(Pt 2):419-31.J Physiol2002-03-01T00:00:002002Differential facilitation of N- and P/Q-type calcium channels during trains of action potential-like waveforms.