Molly Przeworski to Humans
This is a "connection" page, showing publications Molly Przeworski has written about Humans.
Connection Strength
0.686
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The distribution of highly deleterious variants across human ancestry groups. Proc Natl Acad Sci U S A. 2025 May 27; 122(21):e2503857122.
Score: 0.030
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The clock-like accumulation of germline and somatic mutations can arise from the interplay of DNA damage and repair. PLoS Biol. 2024 Jun; 22(6):e3002678.
Score: 0.028
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2023 ASHG Scientific Achievement Award. Am J Hum Genet. 2024 Mar 07; 111(3):425-427.
Score: 0.028
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Relating pathogenic loss-of-function mutations in humans to their evolutionary fitness costs. Elife. 2023 01 17; 12.
Score: 0.025
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A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers. Elife. 2022 08 02; 11.
Score: 0.025
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Lottery, luck, or legacy. A review of "The Genetic Lottery: Why DNA matters for social equality". Evolution. 2022 04 01; 76(4):846-853.
Score: 0.024
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PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
Score: 0.024
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Mutation saturation for fitness effects at human CpG sites. Elife. 2021 11 22; 10.
Score: 0.023
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The evolution of group differences in changing environments. PLoS Biol. 2021 01; 19(1):e3001072.
Score: 0.022
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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions. PLoS Biol. 2020 08; 18(8):e3000838.
Score: 0.022
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Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 2020 01 30; 9.
Score: 0.021
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Signatures of replication timing, recombination, and sex in the spectrum of rare variants on the human X chromosome and autosomes. Proc Natl Acad Sci U S A. 2019 09 03; 116(36):17916-17924.
Score: 0.020
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Overlooked roles of DNA damage and maternal age in generating human germline mutations. Proc Natl Acad Sci U S A. 2019 05 07; 116(19):9491-9500.
Score: 0.020
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Measuring intolerance to mutation in human genetics. Nat Genet. 2019 05; 51(5):772-776.
Score: 0.020
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Contrasting Determinants of Mutation Rates in Germline and Soma. Genetics. 2017 09; 207(1):255-267.
Score: 0.017
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Human Germline Mutation and the Erratic Evolutionary Clock. PLoS Biol. 2016 Oct; 14(10):e2000744.
Score: 0.017
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Variation in the molecular clock of primates. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10607-12.
Score: 0.016
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Interpreting the Dependence of Mutation Rates on Age and Time. PLoS Biol. 2016 Jan; 14(1):e1002355.
Score: 0.016
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An estimate of the average number of recessive lethal mutations carried by humans. Genetics. 2015 Apr; 199(4):1243-54.
Score: 0.015
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TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception. Bioinformatics. 2014 Jul 15; 30(14):2035-42.
Score: 0.014
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The convergent evolution of blue iris pigmentation in primates took distinct molecular paths. Am J Phys Anthropol. 2013 Jul; 151(3):398-407.
Score: 0.013
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Evaluating the evidence for transmission distortion in human pedigrees. Genetics. 2012 May; 191(1):215-32.
Score: 0.012
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Variation in human recombination rates and its genetic determinants. PLoS One. 2011; 6(6):e20321.
Score: 0.011
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Classic selective sweeps were rare in recent human evolution. Science. 2011 Feb 18; 331(6019):920-4.
Score: 0.011
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Genome-sequencing anniversary. The golden age of human population genetics. Science. 2011 Feb 04; 331(6017):547.
Score: 0.011
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Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet. 2009 Sep; 5(9):e1000658.
Score: 0.010
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Natural selection on genes that underlie human disease susceptibility. Curr Biol. 2008 Jun 24; 18(12):883-9.
Score: 0.009
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The timing of selection at the human FOXP2 gene. Mol Biol Evol. 2008 Jul; 25(7):1257-9.
Score: 0.009
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High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science. 2008 Mar 07; 319(5868):1395-8.
Score: 0.009
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An evolutionary view of human recombination. Nat Rev Genet. 2007 Jan; 8(1):23-34.
Score: 0.008
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How reliable are empirical genomic scans for selective sweeps? Genome Res. 2006 Jun; 16(6):702-12.
Score: 0.008
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Genetics. Motivating hotspots. Science. 2005 Oct 14; 310(5746):247-8.
Score: 0.008
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Causal interpretations of family GWAS in the presence of heterogeneous effects. Proc Natl Acad Sci U S A. 2024 Sep 17; 121(38):e2401379121.
Score: 0.007
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Insights into recombination from patterns of linkage disequilibrium in humans. Genetics. 2004 May; 167(1):387-97.
Score: 0.007
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Down the Penrose stairs, or how selection for fewer recombination hotspots maintains their existence. Elife. 2023 10 13; 12.
Score: 0.007
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Limited role of generation time changes in driving the evolution of the mutation spectrum in humans. Elife. 2023 02 13; 12.
Score: 0.006
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Evidence for population growth in humans is confounded by fine-scale population structure. Trends Genet. 2002 Nov; 18(11):559-63.
Score: 0.006
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The signature of positive selection at randomly chosen loci. Genetics. 2002 Mar; 160(3):1179-89.
Score: 0.006
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Impact of essential workers in the context of social distancing for epidemic control. PLoS One. 2021; 16(8):e0255680.
Score: 0.006
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Linkage disequilibrium in humans: models and data. Am J Hum Genet. 2001 Jul; 69(1):1-14.
Score: 0.006
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Why is there so little intragenic linkage disequilibrium in humans? Genet Res. 2001 Apr; 77(2):143-51.
Score: 0.006
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When did the human population size start increasing? Genetics. 2000 Aug; 155(4):1865-74.
Score: 0.005
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Adjusting the focus on human variation. Trends Genet. 2000 Jul; 16(7):296-302.
Score: 0.005
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Deconstructing the sources of genotype-phenotype associations in humans. Science. 2019 09 27; 365(6460):1396-1400.
Score: 0.005
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Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. Elife. 2019 09 24; 8.
Score: 0.005
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The population genetics of human disease: The case of recessive, lethal mutations. PLoS Genet. 2017 Sep; 13(9):e1006915.
Score: 0.004
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Identifying genetic variants that affect viability in large cohorts. PLoS Biol. 2017 Sep; 15(9):e2002458.
Score: 0.004
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A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5652-7.
Score: 0.004
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Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence. PLoS Genet. 2015 Nov; 11(11):e1005658.
Score: 0.004
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Non-crossover gene conversions show strong GC bias and unexpected clustering in humans. Elife. 2015 Mar 25; 4.
Score: 0.004
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Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species. Evolution. 2015 Feb; 69(2):431-46.
Score: 0.004
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Determinants of mutation rate variation in the human germline. Annu Rev Genomics Hum Genet. 2014; 15:47-70.
Score: 0.003
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Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations. Hum Mol Genet. 2013 Dec 01; 22(23):4829-40.
Score: 0.003
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Ancestry runs deeper than blood: the evolutionary history of ABO points to cryptic variation of functional importance. Bioessays. 2013 Oct; 35(10):862-7.
Score: 0.003
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Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science. 2013 Mar 29; 339(6127):1578-82.
Score: 0.003
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A fine-scale chimpanzee genetic map from population sequencing. Science. 2012 Apr 13; 336(6078):193-8.
Score: 0.003
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The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans. PLoS Biol. 2011 Dec; 9(12):e1001211.
Score: 0.003
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PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science. 2010 Feb 12; 327(5967):836-40.
Score: 0.003
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No effect of recombination on the efficacy of natural selection in primates. Genome Res. 2008 Apr; 18(4):544-54.
Score: 0.002
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Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations. Genetics. 2007 Feb; 175(2):795-804.
Score: 0.002
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The rise and fall of the chemoattractant receptor GPR33. J Biol Chem. 2005 Sep 02; 280(35):31068-75.
Score: 0.002
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Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet. 2005 Apr; 37(4):429-34.
Score: 0.002
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Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol. 2004 Jun; 2(6):e155.
Score: 0.002
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Evidence for a complex demographic history of chimpanzees. Mol Biol Evol. 2004 May; 21(5):799-808.
Score: 0.002
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Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biol. 2004 Jan; 2(1):E5.
Score: 0.002
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A neutral explanation for the correlation of diversity with recombination rates in humans. Am J Hum Genet. 2003 Jun; 72(6):1527-35.
Score: 0.002
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Molecular evolution of FOXP2, a gene involved in speech and language. Nature. 2002 Aug 22; 418(6900):869-72.
Score: 0.002
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Evidence for positive selection and population structure at the human MAO-A gene. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):862-7.
Score: 0.001