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linked information resource: Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.

Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.
PubMed Identifier: 30940658
author list: Voce DJ, Bernal GM, Wu L, Crawley CD, Zhang W, Mansour NM, Cahill KE, Szymura SJ, Uppal A, Raleigh DR, Spretz R, Nunez L, Larsen G, Khodarev NN, Weichselbaum RR, Yamini B
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linked information resource: DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy.

DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy.
PubMed Identifier: 32209106
author list: Szymura SJ, Bernal GM, Wu L, Zhang Z, Crawley CD, Voce DJ, Campbell PA, Ranoa DE, Weichselbaum RR, Yamini B
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information resource reference: DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32.
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linked information resource: p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.

p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
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author list: Wu L, Crawley CD, Garofalo A, Nichols JW, Campbell PA, Khramtsova GF, Olopade OI, Weichselbaum RR, Yamini B
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information resource reference: p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
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S Phase
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NF-kappa B
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linked information resource: CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.

CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.
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Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors.
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p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage.
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Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
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author list: Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B
published in: Oncogene
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NF-kappa B p50 Subunit
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linked information resource: Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.

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linked information resource: Loss of Nfkb1 leads to early onset aging.

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linked information resource: S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.

Loss of Nfkb1 leads to early onset aging.
PubMed Identifier: 25553648
author list: Bernal GM, Wahlstrom JS, Crawley CD, Cahill KE, Pytel P, Liang H, Kang S, Weichselbaum RR, Yamini B
published in: Aging
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S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.
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author list: Crawley CD, Kang S, Bernal GM, Wahlstrom JS, Voce DJ, Cahill KE, Garofalo A, Raleigh DR, Weichselbaum RR, Yamini B
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information resource reference: S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76.
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Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
PubMed Identifier: 25808868
author list: Mansour NM, Bernal GM, Wu L, Crawley CD, Cahill KE, Voce DJ, Balyasnikova IV, Zhang W, Spretz R, Nunez L, Larsen GF, Weichselbaum RR, Yamini B
published in: Cancer research
information resource reference: Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. Cancer Res. 2015 May 15; 75(10):2039-48.
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linked information resource: The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
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author list: Giotopoulos G, Chan WI, Horton SJ, Ruau D, Gallipoli P, Fowler A, Crawley C, Papaemmanuil E, Campbell PJ, Göttgens B, Van Deursen JM, Cole PA, Huntly BJ
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information resource reference: The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia. Oncogene. 2016 Jan 21; 35(3):279-89.
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linked information resource: DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.

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sort order: 1
type: Position
HR job title: Research Associate Professor
position in organization: University of Chicago

DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
PubMed Identifier: 23180782
author list: Crawley CD, Raleigh DR, Kang S, Voce DJ, Schmitt AM, Weichselbaum RR, Yamini B
published in: Nucleic acids research
information resource reference: DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site. Nucleic Acids Res. 2013 Jan; 41(2):764-74.
journal title abbreviation: Nucleic Acids Res
publication date: 2012-11-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource