JamesO'DonnellJames O'Donnell41.78927490000000-87.601250000000001833O'Donnell, JamesPostdoctoral Fellowprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000256Living Beings953450.884516AdenoviridaeAuthorship 102543928404627Liew CW, Xu S, Wang X, McCann M, Whang Kong H, Carley AC, Pang J, Fantuzzi G, O'Donnell JM, Lewandowski EDCirculation. Heart failureMultiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy. Circ Heart Fail. 2017 Apr; 10(4).Circ Heart Fail2017-04-01T00:00:002017Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy.KunioDoiKunio Doi41.7886000000000087.598699999999993668Doi, KunioRalph W. Gerard Professor of Biological Sciences, EmeritusObstetrics and GynecologyRadiation and Cellular OncologyMedicine-GastroenterologyD010726Chemicals & Drugs15300.975564Phosphodiesterase InhibitorsAymanAl-HendyAyman Al-Hendy41.7886000000000087.598699999999993954Al-Hendy, AymanProfessor24967639O'Donnell JJ, Birukova AA, Beyer EC, Birukov KGPloS oneGap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014; 9(6):e100931.PLoS One2014-06-26T00:00:002014Gap junction protein connexin43 exacerbates lung vascular permeability.Authorship 1415781Authorship 141656124507900O'Donnell JT, Marks DH, Danese P, O'Donnell JJDisease-a-month : DMDrug-induced liver disease: primer for the primary care physician. Dis Mon. 2014 Feb; 60(2):55-104.Dis Mon2014-02-01T00:00:002014Drug-induced liver disease: primer for the primary care physician.22999026O'Donnell JJ, O'Donnell JT, Juettner VMDisease-a-month : DMClinical pharmacology for the primary care physician. Dis Mon. 2012 Oct; 58(10):558-610.Dis Mon2012-10-01T00:00:002012Clinical pharmacology for the primary care physician.Pediatrics-Hematology and OncologyD009206Anatomy1835280.794457MyocardiumD054678Chemicals & Drugs230.994784Cyclic Nucleotide Phosphodiesterases, Type 2D042783Anatomy1474270.7883Endothelial Cellshttps://scholar.google.com/citations?user=d6I0YqIAAAAJ&hl=enMy Google Scholar siteMedicineRadiologyUniversity of ChicagoEugene B.Chang0mBqA6AbHszMknJtY0fp/Cv/+94=Eugene B. Chang41.78927490000000-87.601250000000001255Chang, Eugene B.ProfessorStephanieMehlisStephanie Mehlis41.78927490000000-87.601250000000001584Mehlis, StephanieClinical Assistant Professor1.54990.00799428216research areas0.1271170.1271171coauthor of15.52284.0622560similar to1124selected publicationsShaileshBajajShailesh Bajaj41.78927490000000-87.6012500000000021Bajaj, ShaileshClinical Assistant ProfessorRalph R.WeichselbaumxXB+DqgWEf/5hHlsaUXv9Gq0+s+oRalph R. Weichselbaum41.78927490000000-87.601250000000002521Weichselbaum, Ralph R.ProfessorLeonardKaplanLeonard Kaplan41.78927490000000-87.601250000000002542Kaplan, LeonardClinical Assistant ProfessorStephenArcherStephen Archer41.78927490000000-87.601250000000002615Archer, StephenProfessorJonathanRichJonathan Rich41.78927490000000-87.6012500000000041Rich, JonathanAsst Prof-Clinical DeptEric C.Beyer0mFrDrgQC8zMknJtY0fp/Cv/+94=Eric C. Beyer41.78927490000000-87.60125000000000459Beyer, Eric C.ProfessorDanielSulmasyDaniel Sulmasy41.78927490000000-87.6012500000000067Sulmasy, DanielEmeritus/Emerita, Professortrue1Asst Prof-Clinical DeptAsst Prof-Clinical Depttrue1Clinical Assistant ProfessorClinical Assistant Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Postdoctoral FellowPostdoctoral Fellowtrue1Clinical Assistant ProfessorClinical Assistant Professortrue1Clinical Assistant ProfessorClinical Assistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Ralph W. Gerard Professor of Biological Sciences, EmeritusRalph W. Gerard Professor of Biological Sciences, EmeritusAuthorship 661251Authorship 655144Authorship 682633Authorship 675682Authorship 687061Authorship 704991Authorship 738791Authorship 776171Authorship 784393Authorship 78811125022754Tian Y, Tian X, Gawlak G, O'Donnell JJ, Sacks DB, Birukova AAMolecular and cellular biologyIQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. Mol Cell Biol. 2014 Sep 15; 34(18):3546-58.Mol Cell Biol2014-07-14T00:00:002014IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.18952713O'Donnell JM, Fields A, Xu X, Chowdhury SA, Geenen DL, Bi JAmerican journal of physiology. Heart and circulatory physiologyLimited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo. Am J Physiol Heart Circ Physiol. 2008 Dec; 295(6):H2483-94.Am J Physiol Heart Circ Physiol2008-10-24T00:00:002008Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo.15789062O'Donnell JM, Lewandowski EDGene therapyEfficient, cardiac-specific adenoviral gene transfer in rat heart by isolated retrograde perfusion in vivo. Gene Ther. 2005 Jun; 12(12):958-64.Gene Ther2005-06-01T00:00:002005Efficient, cardiac-specific adenoviral gene transfer in rat heart by isolated retrograde perfusion in vivo.19744494O'Donnell JM, Pound K, Xu X, Lewandowski EDJournal of molecular and cellular cardiologySERCA1 expression enhances the metabolic efficiency of improved contractility in post-ischemic heart. J Mol Cell Cardiol. 2009 Nov; 47(5):614-21.J Mol Cell Cardiol2009-09-08T00:00:002009SERCA1 expression enhances the metabolic efficiency of improved contractility in post-ischemic heart.22974418O'Donnell JM, Kalichira A, Bi J, Lewandowski EDCurrent gene therapyIn vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native miRNA. Curr Gene Ther. 2012 Dec; 12(6):454-62.Curr Gene Ther2012-12-01T00:00:002012In vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native miRNA.21554891O'Donnell JJ, Zhuge Y, Holian O, Cheng F, Thomas LL, Forsyth CB, Lum HMicrovascular researchLoss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res. 2011 Sep; 82(2):105-12.Microvasc Res2011-04-30T00:00:002011Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells.24706358Gawlak G, Tian Y, O'Donnell JJ, Tian X, Birukova AA, Birukov KGFASEB journal : official publication of the Federation of American Societies for Experimental BiologyPaxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex. FASEB J. 2014 Jul; 28(7):3249-60.FASEB J2014-04-04T00:00:002014Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.24985472Cowan C, Muraleedharan CK, O'Donnell JJ, Singh PK, Lum H, Kumar A, Xu SInvestigative ophthalmology & visual scienceMicroRNA-146 inhibits thrombin-induced NF-?B activation and subsequent inflammatory responses in human retinal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 01; 55(8):4944-51.Invest Ophthalmol Vis Sci2014-07-01T00:00:002014MicroRNA-146 inhibits thrombin-induced NF-?B activation and subsequent inflammatory responses in human retinal endothelial cells.20382170Zhang J, O'Donnell JJ, Holian O, Vincent PA, Kim KS, Lum HMicrovascular researchP120 catenin represses transcriptional activity through Kaiso in endothelial cells. Microvasc Res. 2010 Sep; 80(2):233-9.Microvasc Res2010-04-09T00:00:002010P120 catenin represses transcriptional activity through Kaiso in endothelial cells.Authorship 80876125199499O'Donnell JM, Fasano MJ, Lewandowski EDMagnetic resonance in medicineResolving confounding enrichment kinetics due to overlapping resonance signals from 13C-enriched long chain fatty acid oxidation and uptake within intact hearts. Magn Reson Med. 2015 Aug; 74(2):330-5.Magn Reson Med2014-09-08T00:00:002014Resolving confounding enrichment kinetics due to overlapping resonance signals from 13C-enriched long chain fatty acid oxidation and uptake within intact hearts.Chicago60637ILAuthorship 86885618327406Hochart H, Jenkins PV, Preston RJ, Smith OP, White B, O'Donnell JThrombosis and haemostasisConcentration-dependent roles for heparin in modifying lipopolysaccharide-induced activation of mononuclear cells in whole blood. Thromb Haemost. 2008 Mar; 99(3):570-5.Thromb Haemost2008-03-01T00:00:002008Concentration-dependent roles for heparin in modifying lipopolysaccharide-induced activation of mononuclear cells in whole blood.Authorship 89507327128976Tian Y, Gawlak G, O'Donnell JJ, Mambetsariev I, Birukova AAPloS oneModulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch. PLoS One. 2016; 11(4):e0153387.PLoS One2016-04-29T00:00:002016Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch.Authorship 89835326884340Tian Y, Gawlak G, O'Donnell JJ, Birukova AA, Birukov KGThe Journal of biological chemistryActivation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch. J Biol Chem. 2016 May 06; 291(19):10032-45.J Biol Chem2016-02-16T00:00:002016Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch.Authorship 9021110Authorship 902155Authorship 901884Authorship 902071426993523Gawlak G, Son S, Tian Y, O'Donnell JJ, Birukov KG, Birukova AAAmerican journal of physiology. Lung cellular and molecular physiologyChronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism. Am J Physiol Lung Cell Mol Physiol. 2016 06 01; 310(11):L1062-70.Am J Physiol Lung Cell Mol Physiol2016-03-18T00:00:002016Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism.22850435Xu Y, Pan J, Chen L, Zhang C, Sun J, Li J, Nguyen L, Nair N, Zhang H, O'Donnell JMThe international journal of neuropsychopharmacologyPhosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. Int J Neuropsychopharmacol. 2013 May; 16(4):835-47.Int J Neuropsychopharmacol2012-07-31T00:00:002012Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway.17407767Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ, O'Donnell JMBrain researchChanges in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures. Brain Res. 2007 May 29; 1149:58-68.Brain Res2007-03-12T00:00:002007Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures.25442113Xu Y, Pan J, Sun J, Ding L, Ruan L, Reed M, Yu X, Klabnik J, Lin D, Li J, Chen L, Zhang C, Zhang H, O'Donnell JMNeurobiology of agingInhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress. Neurobiol Aging. 2015 Feb; 36(2):955-70.Neurobiol Aging2014-08-30T00:00:002014Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress.Authorship 90681527178174Subbaiah PV, Dammanahalli KJ, Yang P, Bi J, O'Donnell JMBiochimica et biophysica actaEnhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier. Biochim Biophys Acta. 2016 Aug; 1861(8 Pt A):723-9.Biochim Biophys Acta2016-05-10T00:00:002016Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier.Authorship 962347Authorship 964931216681646Hollestelle MJ, Donkor C, Mantey EA, Chakravorty SJ, Craig A, Akoto AO, O'Donnell J, van Mourik JA, Bunn JBritish journal of haematologyvon Willebrand factor propeptide in malaria: evidence of acute endothelial cell activation. Br J Haematol. 2006 Jun; 133(5):562-9.Br J Haematol2006-06-01T00:00:002006von Willebrand factor propeptide in malaria: evidence of acute endothelial cell activation.23003922Wang ZZ, Zhang Y, Liu YQ, Zhao N, Zhang YZ, Yuan L, An L, Li J, Wang XY, Qin JJ, Wilson SP, O'Donnell JM, Zhang HT, Li YFBritish journal of pharmacologyRNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects. Br J Pharmacol. 2013 Feb; 168(4):1001-14.Br J Pharmacol2013-02-01T00:00:002013RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects.