Joseph Piccirilli to Catalysis
This is a "connection" page, showing publications Joseph Piccirilli has written about Catalysis.
Connection Strength
1.829
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Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat Chem Biol. 2022 04; 18(4):376-384.
Score: 0.176
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RNA catalyses nuclear pre-mRNA splicing. Nature. 2013 Nov 14; 503(7475):229-34.
Score: 0.099
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Thermodynamic evidence for negative charge stabilization by a catalytic metal ion within an RNA active site. ACS Chem Biol. 2012 Feb 17; 7(2):294-9.
Score: 0.087
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Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment. Philos Trans R Soc Lond B Biol Sci. 2011 Oct 27; 366(1580):2918-28.
Score: 0.086
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The mechanism of peptidyl transfer catalysis by the ribosome. Annu Rev Biochem. 2011; 80:527-55.
Score: 0.082
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A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site. Biochemistry. 2010 Mar 30; 49(12):2753-62.
Score: 0.077
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Identification of catalytic metal ion ligands in ribozymes. Methods. 2009 Oct; 49(2):148-66.
Score: 0.074
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Efficient chemical synthesis of AppDNA by adenylation of immobilized DNA-5'-monophosphate. Org Lett. 2009 Mar 05; 11(5):1067-70.
Score: 0.072
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Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis. Bioorg Med Chem. 2008 May 15; 16(10):5754-60.
Score: 0.067
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Linkage between substrate recognition and catalysis during cleavage of sarcin/ricin loop RNA by restrictocin. Biochemistry. 2007 Nov 06; 46(44):12744-56.
Score: 0.065
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Nucleotide analogues to investigate RNA structure and function. Curr Opin Chem Biol. 2005 Dec; 9(6):585-93.
Score: 0.057
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Functional identification of catalytic metal ion binding sites within RNA. PLoS Biol. 2005 Sep; 3(9):e277.
Score: 0.056
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General acid catalysis by the hepatitis delta virus ribozyme. Nat Chem Biol. 2005 Jun; 1(1):45-52.
Score: 0.055
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New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis. Chem Biol. 2004 Feb; 11(2):237-46.
Score: 0.051
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Rapid Kinetics of Pistol Ribozyme: Insights into Limits to RNA Catalysis. Biochemistry. 2023 07 04; 62(13):2079-2092.
Score: 0.048
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Dissociative Transition State in Hepatitis Delta Virus Ribozyme Catalysis. J Am Chem Soc. 2023 02 08; 145(5):2830-2839.
Score: 0.047
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Leaving group stabilization by metal ion coordination and hydrogen bond donation is an evolutionarily conserved feature of group I introns. Biochim Biophys Acta. 2001 Dec 30; 1522(3):158-66.
Score: 0.044
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Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis. Nat Struct Biol. 2001 Oct; 8(10):893-8.
Score: 0.043
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The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions. Biochemistry. 2001 Sep 18; 40(37):10911-26.
Score: 0.043
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Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis. Biochemistry. 2000 Oct 24; 39(42):12939-52.
Score: 0.040
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The role of the cleavage site 2'-hydroxyl in the Tetrahymena group I ribozyme reaction. Chem Biol. 2000 Feb; 7(2):85-96.
Score: 0.038
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Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns. RNA. 2000 Feb; 6(2):199-205.
Score: 0.038
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The L-platform/L-scaffold framework: a blueprint for RNA-cleaving nucleic acid enzyme design. RNA. 2020 02; 26(2):111-125.
Score: 0.038
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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome. Genes Dev. 1999 Jul 01; 13(13):1729-41.
Score: 0.037
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An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes. ACS Chem Biol. 2019 06 21; 14(6):1068-1076.
Score: 0.037
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Metal ion catalysis during splicing of premessenger RNA. Nature. 1997 Aug 21; 388(6644):801-5.
Score: 0.032
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Isotope effect analyses provide evidence for an altered transition state for RNA 2'-O-transphosphorylation catalyzed by Zn(2+). Chem Commun (Camb). 2016 Mar 25; 52(24):4462-5.
Score: 0.029
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An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions. RNA. 2016 Jan; 22(1):32-48.
Score: 0.029
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Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature. 1993 Jan 07; 361(6407):85-8.
Score: 0.023
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General acid-base catalysis mediated by nucleobases in the hairpin ribozyme. J Am Chem Soc. 2012 Oct 10; 134(40):16717-24.
Score: 0.023
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A C-nucleotide base pair: methylpseudouridine-directed incorporation of formycin triphosphate into RNA catalyzed by T7 RNA polymerase. Biochemistry. 1991 Oct 22; 30(42):10350-6.
Score: 0.022
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Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme. Proc Natl Acad Sci U S A. 2010 Jun 29; 107(26):11751-6.
Score: 0.020
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Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science. 2009 Nov 27; 326(5957):1271-5.
Score: 0.019
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Structure and function converge to identify a hydrogen bond in a group I ribozyme active site. Angew Chem Int Ed Engl. 2009; 48(39):7171-5.
Score: 0.018
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Functional identification of ligands for a catalytic metal ion in group I introns. Biochemistry. 2008 Jul 01; 47(26):6883-94.
Score: 0.017
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Identification of an active site ligand for a group I ribozyme catalytic metal ion. Biochemistry. 2002 Feb 26; 41(8):2516-25.
Score: 0.011
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Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction. Biochemistry. 2001 May 01; 40(17):5161-71.
Score: 0.010
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Three metal ions at the active site of the Tetrahymena group I ribozyme. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12299-304.
Score: 0.009
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Redesigning nucleic acids. Pure Appl Chem. 1998 Feb; 70(2):263-6.
Score: 0.008