Joseph Piccirilli to Introns
This is a "connection" page, showing publications Joseph Piccirilli has written about Introns.
Connection Strength
1.878
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Biochemistry. Toward understanding self-splicing. Science. 2008 Apr 04; 320(5872):56-7.
Score: 0.265
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A second divalent metal ion in the group II intron reaction center. Chem Biol. 2007 Jun; 14(6):607-12.
Score: 0.250
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New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis. Chem Biol. 2004 Feb; 11(2):237-46.
Score: 0.198
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Leaving group stabilization by metal ion coordination and hydrogen bond donation is an evolutionarily conserved feature of group I introns. Biochim Biophys Acta. 2001 Dec 30; 1522(3):158-66.
Score: 0.172
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Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis. Nat Struct Biol. 2001 Oct; 8(10):893-8.
Score: 0.169
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Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis. Biochemistry. 2000 Oct 24; 39(42):12939-52.
Score: 0.158
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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome. Genes Dev. 1999 Jul 01; 13(13):1729-41.
Score: 0.144
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RNA catalyses nuclear pre-mRNA splicing. Nature. 2013 Nov 14; 503(7475):229-34.
Score: 0.098
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Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding. RNA. 2012 Jun; 18(6):1123-41.
Score: 0.088
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The 2'-hydroxyl group of the guanosine nucleophile donates a functionally important hydrogen bond in the tetrahymena ribozyme reaction. Biochemistry. 2008 Jul 22; 47(29):7684-94.
Score: 0.067
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Functional identification of ligands for a catalytic metal ion in group I introns. Biochemistry. 2008 Jul 01; 47(26):6883-94.
Score: 0.067
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Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis. Bioorg Med Chem. 2008 May 15; 16(10):5754-60.
Score: 0.066
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Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes. Nat Commun. 2025 Jan 26; 16(1):1047.
Score: 0.053
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Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns. RNA. 2000 Feb; 6(2):199-205.
Score: 0.038
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Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature. 1993 Jan 07; 361(6407):85-8.
Score: 0.023
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Structure and function converge to identify a hydrogen bond in a group I ribozyme active site. Angew Chem Int Ed Engl. 2009; 48(39):7171-5.
Score: 0.017
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RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization. J Biol Chem. 1992 Sep 05; 267(25):17479-82.
Score: 0.006