The University of Chicago Header Logo

Connection

Hans Schreiber to Animals

This is a "connection" page, showing publications Hans Schreiber has written about Animals.
Connection Strength

1.254
  1. CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy. Sci Immunol. 2024 09 13; 9(99):eadp6529.
    View in: PubMed
    Score: 0.055
  2. Criteria to make animal studies more relevant to treating human cancer. Curr Opin Immunol. 2022 02; 74:25-31.
    View in: PubMed
    Score: 0.045
  3. Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication. Cancer Immunol Res. 2017 02; 5(2):127-136.
    View in: PubMed
    Score: 0.032
  4. Tumor-associated fibroblasts predominantly come from local and not circulating precursors. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7551-6.
    View in: PubMed
    Score: 0.031
  5. Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 06 01; 22(11):2734-43.
    View in: PubMed
    Score: 0.030
  6. Editorial overview: tumour immunology. Curr Opin Immunol. 2015 Apr; 33:ix-xi.
    View in: PubMed
    Score: 0.029
  7. Targeting cancer-specific mutations by T cell receptor gene therapy. Curr Opin Immunol. 2015 Apr; 33:112-9.
    View in: PubMed
    Score: 0.028
  8. Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors--letter. Cancer Res. 2014 Jan 15; 74(2):632; discussion 635.
    View in: PubMed
    Score: 0.026
  9. Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression. J Immunol. 2014 Feb 01; 192(3):1286-93.
    View in: PubMed
    Score: 0.026
  10. Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 2013 Apr 15; 23(4):516-26.
    View in: PubMed
    Score: 0.025
  11. Spleen cells from young but not old immunized mice eradicate large established cancers. Clin Cancer Res. 2012 May 01; 18(9):2526-33.
    View in: PubMed
    Score: 0.023
  12. Densely granulated murine NK cells eradicate large solid tumors. Cancer Res. 2012 Apr 15; 72(8):1964-74.
    View in: PubMed
    Score: 0.023
  13. Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity. Mol Ther. 2012 Mar; 20(3):652-60.
    View in: PubMed
    Score: 0.023
  14. Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes. Cancer Immun. 2011 Jun 30; 11:2.
    View in: PubMed
    Score: 0.022
  15. Cancer. Awakening immunity. Science. 2010 Nov 05; 330(6005):761-2.
    View in: PubMed
    Score: 0.021
  16. Bystander killing of cancer requires the cooperation of CD4(+) and CD8(+) T cells during the effector phase. J Exp Med. 2010 Oct 25; 207(11):2469-77.
    View in: PubMed
    Score: 0.021
  17. Ribosomal versus non-ribosomal cellular antigens: factors determining efficiency of indirect presentation to CD4+ T cells. Immunology. 2010 Aug; 130(4):494-503.
    View in: PubMed
    Score: 0.020
  18. Tumor-specific immune responses. Semin Immunol. 2008 Oct; 20(5):265-6.
    View in: PubMed
    Score: 0.018
  19. Specificity in cancer immunotherapy. Semin Immunol. 2008 Oct; 20(5):276-85.
    View in: PubMed
    Score: 0.018
  20. IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers. J Clin Invest. 2008 Apr; 118(4):1398-404.
    View in: PubMed
    Score: 0.018
  21. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Res. 2008 Mar 01; 68(5):1563-71.
    View in: PubMed
    Score: 0.017
  22. Cancer. Quo vadis, specificity? Science. 2008 Jan 11; 319(5860):164-5.
    View in: PubMed
    Score: 0.017
  23. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J Exp Med. 2007 Jan 22; 204(1):49-55.
    View in: PubMed
    Score: 0.016
  24. The terminology issue for myeloid-derived suppressor cells. Cancer Res. 2007 Jan 01; 67(1):425; author reply 426.
    View in: PubMed
    Score: 0.016
  25. A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science. 2006 Oct 13; 314(5797):304-8.
    View in: PubMed
    Score: 0.016
  26. Floxed reporter genes: Flow-cytometric selection of clonable cells expressing high levels of a target gene after tamoxifen-regulated Cre-loxP recombination. J Immunol Methods. 2006 May 30; 312(1-2):201-8.
    View in: PubMed
    Score: 0.015
  27. The role of stroma in immune recognition and destruction of well-established solid tumors. Curr Opin Immunol. 2006 Apr; 18(2):226-31.
    View in: PubMed
    Score: 0.015
  28. Mutant p53-specific CD8TCR-therapy combined with a CD4TCR prevents relapse of cancer and outgrowth of micrometastases. Oncoimmunology. 2025 Dec; 14(1):2514041.
    View in: PubMed
    Score: 0.014
  29. Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells. Cancer Immun. 2005 Jun 06; 5:8.
    View in: PubMed
    Score: 0.014
  30. Selection of therapeutically effective T-cell receptors from the diverse tumor-bearing repertoire. J Immunother Cancer. 2025 May 02; 13(5).
    View in: PubMed
    Score: 0.014
  31. Inflammation as a tumor promoter in cancer induction. Semin Cancer Biol. 2004 Dec; 14(6):433-9.
    View in: PubMed
    Score: 0.014
  32. Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene. 2004 May 13; 23(22):3972-9.
    View in: PubMed
    Score: 0.013
  33. Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-gamma pathway but not IL-12 or IL-18. J Immunol. 2004 Mar 01; 172(5):3243-51.
    View in: PubMed
    Score: 0.013
  34. Bystander elimination of antigen loss variants in established tumors. Nat Med. 2004 Mar; 10(3):294-8.
    View in: PubMed
    Score: 0.013
  35. The safety and efficacy of systemic delivery of a new liver-de-targeted TGFß signaling inhibiting adenovirus in an immunocompetent triple negative mouse mammary tumor model. Cancer Gene Ther. 2024 Apr; 31(4):574-585.
    View in: PubMed
    Score: 0.013
  36. Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation. Curr Opin Immunol. 2003 Dec; 15(6):725-30.
    View in: PubMed
    Score: 0.013
  37. Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. J Immunother Cancer. 2023 05; 11(5).
    View in: PubMed
    Score: 0.013
  38. Genetic changes occurring in established tumors rapidly stimulate new antibody responses. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5425-30.
    View in: PubMed
    Score: 0.012
  39. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 2002 Dec; 17(6):737-47.
    View in: PubMed
    Score: 0.012
  40. Immunodominance and tumor escape. Semin Cancer Biol. 2002 Feb; 12(1):25-31.
    View in: PubMed
    Score: 0.011
  41. Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens. J Exp Med. 2001 Aug 06; 194(3):285-300.
    View in: PubMed
    Score: 0.011
  42. Tracking the common ancestry of antigenically distinct cancer variants. Clin Cancer Res. 2001 Mar; 7(3 Suppl):871s-875s.
    View in: PubMed
    Score: 0.011
  43. Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. 2020 11 13; 41(11):1605-1615.
    View in: PubMed
    Score: 0.011
  44. Immunological enhancement of primary tumor development and its prevention. Semin Cancer Biol. 2000 Oct; 10(5):351-7.
    View in: PubMed
    Score: 0.010
  45. Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15148-15159.
    View in: PubMed
    Score: 0.010
  46. LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor ß Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models. Hum Gene Ther. 2020 08; 31(15-16):863-880.
    View in: PubMed
    Score: 0.010
  47. Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein. J Exp Med. 2000 Jun 05; 191(11):1945-56.
    View in: PubMed
    Score: 0.010
  48. Automated cell cluster analysis provides insight into multi-cell-type interactions between immune cells and their targets. Exp Cell Res. 2020 08 15; 393(2):112014.
    View in: PubMed
    Score: 0.010
  49. Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors. Cancer Immunol Res. 2020 02; 8(2):192-202.
    View in: PubMed
    Score: 0.010
  50. Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 11 01; 4(21).
    View in: PubMed
    Score: 0.010
  51. Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen-Specific T Cells. Clin Cancer Res. 2020 02 01; 26(3):679-689.
    View in: PubMed
    Score: 0.010
  52. TCR-pMHC bond conformation controls TCR ligand discrimination. Cell Mol Immunol. 2020 03; 17(3):203-217.
    View in: PubMed
    Score: 0.010
  53. CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8633-8.
    View in: PubMed
    Score: 0.010
  54. A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody. Glycobiology. 2019 04 01; 29(4):307-319.
    View in: PubMed
    Score: 0.009
  55. Tumor cells induce cytolytic T cells to a single immunodominant mutant peptide. J Immunother. 1998 Jul; 21(4):277-82.
    View in: PubMed
    Score: 0.009
  56. Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J Exp Med. 1997 Jul 21; 186(2):229-38.
    View in: PubMed
    Score: 0.008
  57. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017 05 04; 545(7652):98-102.
    View in: PubMed
    Score: 0.008
  58. The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68. J Exp Med. 1997 Feb 17; 185(4):695-705.
    View in: PubMed
    Score: 0.008
  59. Radiation can inhibit tumor growth indirectly while depleting circulating leukocytes. Radiat Res. 1996 Dec; 146(6):612-8.
    View in: PubMed
    Score: 0.008
  60. Unique tumor antigens redefined as mutant tumor-specific antigens. Semin Immunol. 1996 Oct; 8(5):289-93.
    View in: PubMed
    Score: 0.008
  61. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma. Immunity. 2016 06 21; 44(6):1444-54.
    View in: PubMed
    Score: 0.008
  62. Immunodominance deters the response to other tumor antigens thereby favoring escape: prevention by vaccination with tumor variants selected with cloned cytolytic T cells in vitro. Tissue Antigens. 1996 May; 47(5):399-407.
    View in: PubMed
    Score: 0.008
  63. Antigenic cancer cells that escape immune destruction are stimulated by host cells. Cancer Res. 1995 Nov 01; 55(21):5094-100.
    View in: PubMed
    Score: 0.007
  64. Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. Proc Natl Acad Sci U S A. 1995 Jul 03; 92(14):6254-8.
    View in: PubMed
    Score: 0.007
  65. A unique tumor antigen produced by a single amino acid substitution. Immunity. 1995 Jan; 2(1):45-59.
    View in: PubMed
    Score: 0.007
  66. Inhibition of tumor growth by elimination of granulocytes. J Exp Med. 1995 Jan 01; 181(1):435-40.
    View in: PubMed
    Score: 0.007
  67. Tumors with reduced expression of a cytotoxic T lymphocyte recognized antigen lack immunogenicity but retain sensitivity to lysis by cytotoxic T lymphocytes. Eur J Immunol. 1993 Nov; 23(11):2770-6.
    View in: PubMed
    Score: 0.006
  68. Prevention of runting and cachexia by a chimeric TNF receptor-Fc protein. Clin Immunol Immunopathol. 1993 Nov; 69(2):215-22.
    View in: PubMed
    Score: 0.006
  69. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol. 2013 Oct; 14(10):1014-22.
    View in: PubMed
    Score: 0.006
  70. A tumor escape variant that has lost one major histocompatibility complex class I restriction element induces specific CD8+ T cells to an antigen that no longer serves as a target. J Exp Med. 1993 Sep 01; 178(3):933-40.
    View in: PubMed
    Score: 0.006
  71. Genetically engineered vaccines. Comparison of active versus passive immunotherapy against solid tumors. Ann N Y Acad Sci. 1993 Aug 12; 690:244-55.
    View in: PubMed
    Score: 0.006
  72. Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer. Cancer Immunol Res. 2013 Aug; 1(2):123-33.
    View in: PubMed
    Score: 0.006
  73. CD4-positive and B lymphocytes in transplantation immunity. I. Promotion of tumor allograft rejection through elimination of CD4-positive lymphocytes. Transplantation. 1993 Jun; 55(6):1349-55.
    View in: PubMed
    Score: 0.006
  74. Footprinting of individual tumors and their variants by constitutive cytokine expression patterns. Cancer Res. 1993 May 01; 53(9):1978-81.
    View in: PubMed
    Score: 0.006
  75. IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8158-63.
    View in: PubMed
    Score: 0.006
  76. DNA sequence analysis of T-cell receptor genes reveals an oligoclonal T-cell response to a tumor with multiple target antigens. Cancer Res. 1993 Feb 15; 53(4):840-5.
    View in: PubMed
    Score: 0.006
  77. Design and characterization of a protein superagonist of IL-15 fused with IL-15Ra and a high-affinity T cell receptor. Biotechnol Prog. 2012 Nov-Dec; 28(6):1588-97.
    View in: PubMed
    Score: 0.006
  78. MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR. Cancer Immunol Immunother. 2013 Feb; 62(2):359-69.
    View in: PubMed
    Score: 0.006
  79. Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J Exp Med. 1992 Jan 01; 175(1):139-46.
    View in: PubMed
    Score: 0.006
  80. MHC class I restricted T cells and immune surveillance against transplanted ultraviolet light-induced tumors. Semin Cancer Biol. 1991 Oct; 2(5):321-8.
    View in: PubMed
    Score: 0.006
  81. Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3535-9.
    View in: PubMed
    Score: 0.005
  82. Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance. Cancer Res. 1990 Jul 01; 50(13):3851-8.
    View in: PubMed
    Score: 0.005
  83. Antibody recognition of a unique tumor-specific glycopeptide antigen. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10056-61.
    View in: PubMed
    Score: 0.005
  84. Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. J Exp Med. 1990 Apr 01; 171(4):1205-20.
    View in: PubMed
    Score: 0.005
  85. Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells. J Immunol. 2009 Aug 01; 183(3):1828-37.
    View in: PubMed
    Score: 0.005
  86. Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells. J Exp Med. 1989 Jul 01; 170(1):217-32.
    View in: PubMed
    Score: 0.005
  87. Highly immunogenic regressor tumor cells can prevent development of postsurgical tumor immunity. Cell Immunol. 1989 Mar; 119(1):101-13.
    View in: PubMed
    Score: 0.005
  88. Tumor-specific antigens and tumor-specific mutant proteins in mouse and man. Haematol Blood Transfus. 1989; 32:284-8.
    View in: PubMed
    Score: 0.005
  89. Tumor necrosis factor/cachectin. Induction of hemorrhagic necrosis in normal tissue requires the fifth component of complement (C5). J Exp Med. 1988 Dec 01; 168(6):2007-21.
    View in: PubMed
    Score: 0.005
  90. Unique tumor-specific antigens. Annu Rev Immunol. 1988; 6:465-83.
    View in: PubMed
    Score: 0.004
  91. Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice. Proc Natl Acad Sci U S A. 1988 Jan; 85(2):607-11.
    View in: PubMed
    Score: 0.004
  92. Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases. J Immunol. 2007 Aug 01; 179(3):1960-8.
    View in: PubMed
    Score: 0.004
  93. Relationship of tumour necrosis factor and endotoxin to macrophage cytotoxicity, haemorrhagic necrosis and lethal shock. Ciba Found Symp. 1987; 131:124-39.
    View in: PubMed
    Score: 0.004
  94. Identification of a gene encoding a tumor-specific antigen that causes tumor rejection. Haematol Blood Transfus. 1987; 31:308-13.
    View in: PubMed
    Score: 0.004
  95. Cancer immunotherapy and preclinical studies: why we are not wasting our time with animal experiments. Hematol Oncol Clin North Am. 2006 Jun; 20(3):567-84.
    View in: PubMed
    Score: 0.004
  96. CD40 ligation restores cytolytic T lymphocyte response and eliminates fibrosarcoma in the peritoneum of mice lacking CD4+ T cells. Cancer Immunol Immunother. 2006 Dec; 55(12):1542-52.
    View in: PubMed
    Score: 0.004
  97. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J Exp Med. 2005 Mar 07; 201(5):779-91.
    View in: PubMed
    Score: 0.004
  98. A new murine tumor model for studying HLA-A2-restricted anti-tumor immunity. Cancer Lett. 2005 Jun 16; 224(1):153-66.
    View in: PubMed
    Score: 0.004
  99. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat Immunol. 2004 Feb; 5(2):141-9.
    View in: PubMed
    Score: 0.003
  100. Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells. J Exp Med. 2003 Apr 21; 197(8):985-95.
    View in: PubMed
    Score: 0.003
  101. C-kit+ FcR+ myelocytes are increased in cancer and prevent the proliferation of fully cytolytic T cells in the presence of immune serum. Eur J Immunol. 2003 Jan; 33(1):19-28.
    View in: PubMed
    Score: 0.003
  102. Establishment of an HLA-A*0201 human papillomavirus type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice. Cancer Res. 2002 Oct 15; 62(20):5792-9.
    View in: PubMed
    Score: 0.003
  103. Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide. J Immunol. 2001 Jun 15; 166(12):7151-7.
    View in: PubMed
    Score: 0.003
  104. Role of TGF-beta in immune-evasion of cancer. Microsc Res Tech. 2001 Feb 15; 52(4):387-95.
    View in: PubMed
    Score: 0.003
  105. Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation. Int J Oncol. 1999 Oct; 15(4):769-73.
    View in: PubMed
    Score: 0.002
  106. Active immunization against cancer cells: impediments and advances. Semin Oncol. 1998 Dec; 25(6):697-706.
    View in: PubMed
    Score: 0.002
  107. CD4+ and B lymphocytes in transplantation immunity. II. Augmented rejection of tumor allografts by mice lacking B cells. Transplantation. 1993 Jun; 55(6):1356-61.
    View in: PubMed
    Score: 0.002
  108. Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice. Genes Dev. 1992 Aug; 6(8):1444-56.
    View in: PubMed
    Score: 0.001
  109. Mechanism of tumor rejection in anti-CD3 monoclonal antibody-treated mice. J Immunol. 1990 Apr 01; 144(7):2840-6.
    View in: PubMed
    Score: 0.001
  110. A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1486-90.
    View in: PubMed
    Score: 0.001
  111. In vivo administration of anti-CD3 prevents malignant progressor tumor growth. Science. 1988 Oct 28; 242(4878):569-71.
    View in: PubMed
    Score: 0.001
  112. [CA 12-5 in cancer of the digestive tract. A comparison with CA 19-9 and CEA in cancer of the pancreas and colon]. Dtsch Med Wochenschr. 1984 Dec 21; 109(51-52):1949-54.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.