Graeme Bell to Animals
This is a "connection" page, showing publications Graeme Bell has written about Animals.
Connection Strength
0.821
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Three Strikes and You're Cured. Sci Transl Med. 2012 May 09; 4(133):133fs12.
Score: 0.027
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Intrapancreatic delivery of human umbilical cord blood aldehyde dehydrogenase-producing cells promotes islet regeneration. Diabetologia. 2012 Jun; 55(6):1755-60.
Score: 0.027
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Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1449-54.
Score: 0.023
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The oligogenic view of adaptation. Cold Spring Harb Symp Quant Biol. 2009; 74:139-44.
Score: 0.023
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Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice. Horm Metab Res. 2009 Jan; 41(1):1-4.
Score: 0.021
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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61.
Score: 0.020
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Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene. Genesis. 2005 Oct; 43(2):80-6.
Score: 0.017
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Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway. Int J Biochem Cell Biol. 2005 Jul; 37(7):1421-37.
Score: 0.017
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Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1. Gene. 2005 Jan 03; 344:143-59.
Score: 0.016
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Organ alchemy: producing insulin in the liver. Nat Med. 2003 May; 9(5):504-5.
Score: 0.015
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Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E177-83.
Score: 0.014
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Diabetes mellitus and genetically programmed defects in beta-cell function. Nature. 2001 Dec 13; 414(6865):788-91.
Score: 0.013
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Purification of multiple heat shock proteins from a single tumor sample. J Immunol Methods. 2000 Apr 03; 237(1-2):119-30.
Score: 0.012
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019 06; 570(7759):71-76.
Score: 0.011
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A One Health investigation of Salmonella enterica serovar Wangata in north-eastern New South Wales, Australia, 2016-2017. Epidemiol Infect. 2019 01; 147:e150.
Score: 0.011
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Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes. Diabetes. 1997 Sep; 46(9):1434-9.
Score: 0.010
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Identification of gestationally regulated genes in rat myometrium by use of messenger ribonucleic acid differential display. Am J Obstet Gynecol. 1997 Sep; 177(3):645-52.
Score: 0.010
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Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats. Biochem Biophys Res Commun. 1997 Aug 18; 237(2):476-80.
Score: 0.010
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In vivo measurement and biological characterisation of the diabetes-associated mutant insulin p.R46Q (GlnB22-insulin). Diabetologia. 2017 08; 60(8):1423-1431.
Score: 0.010
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The length distribution of perfect dimer repetitive DNA is consistent with its evolution by an unbiased single-step mutation process. J Mol Evol. 1997 Apr; 44(4):414-21.
Score: 0.010
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Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4. Diabetes. 1997 Mar; 46(3):528-35.
Score: 0.010
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature. 1996 Dec 05; 384(6608):455-8.
Score: 0.009
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JAK/STAT eats the fat. Trends Neurosci. 1996 May; 19(5):159-61.
Score: 0.009
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Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med. 1996 Mar 21; 334(12):777-83.
Score: 0.009
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Resting beta-cells - A functional reserve? Diabetes Metab. 2016 Jun; 42(3):157-61.
Score: 0.009
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Glucokinase mutations, insulin secretion, and diabetes mellitus. Annu Rev Physiol. 1996; 58:171-86.
Score: 0.009
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Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes. 1995 Dec; 44(12):1447-57.
Score: 0.009
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Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library. Genomics. 1995 Sep 01; 29(1):276-81.
Score: 0.009
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Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization. Genomics. 1995 Aug 10; 28(3):607-9.
Score: 0.009
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Molecular properties of somatostatin receptors. Neuroscience. 1995 Aug; 67(4):777-90.
Score: 0.009
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Molecular biology of somatostatin receptors. Endocr Rev. 1995 Aug; 16(4):427-42.
Score: 0.009
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Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochem Biophys Res Commun. 1995 Jul 26; 212(3):894-9.
Score: 0.009
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Cloning of rat and mouse P2Y purinoceptors. Biochem Biophys Res Commun. 1995 Jun 06; 211(1):211-8.
Score: 0.008
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Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E978-89.
Score: 0.008
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Molecular biology of somatostatin receptors. Ciba Found Symp. 1995; 190:65-79; discussion 80-8.
Score: 0.008
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Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice. Hum Mol Genet. 2015 Mar 15; 24(6):1646-54.
Score: 0.008
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Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7. Genomics. 1994 Oct; 23(3):697-9.
Score: 0.008
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Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7777-81.
Score: 0.008
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Distribution of kappa opioid receptor mRNA in adult mouse brain: an in situ hybridization histochemistry study. Mol Cell Neurosci. 1994 Aug; 5(4):327-35.
Score: 0.008
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Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism. Genomics. 1994 May 01; 21(1):254-6.
Score: 0.008
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Role of BH3-only molecules Bim and Puma in ß-cell death in Pdx1 deficiency. Diabetes. 2014 Aug; 63(8):2744-50.
Score: 0.008
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Localization of the kappa opioid receptor gene to human chromosome band 8q11.2. Genomics. 1994 Feb; 19(3):596-7.
Score: 0.008
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Molecular biology of opioid receptors. Trends Neurosci. 1993 Dec; 16(12):506-10.
Score: 0.008
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Human hexokinase II: localization of the polymorphic gene to chromosome 2. Diabetologia. 1993 Dec; 36(12):1299-302.
Score: 0.008
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Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb; 196(2):539-55.
Score: 0.008
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Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb; 196(2):557-67.
Score: 0.008
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A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones. Hum Mol Genet. 1993 Nov; 2(11):1793-8.
Score: 0.008
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Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase. Mol Pharmacol. 1993 Nov; 44(5):1016-20.
Score: 0.008
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Structure and function of mammalian facilitative sugar transporters. J Biol Chem. 1993 Sep 15; 268(26):19161-4.
Score: 0.007
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GSK-3ß function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 2013 Oct; 154(10):3702-18.
Score: 0.007
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Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6736-40.
Score: 0.007
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Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin. PLoS One. 2013; 8(6):e65777.
Score: 0.007
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Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues. J Biol Chem. 1993 May 25; 268(15):11356-63.
Score: 0.007
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Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism. Diabetologia. 1993 Apr; 36(4):335-7.
Score: 0.007
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Assignment of human potassium channel gene KCNA4 (Kv1.4, PCN2) to chromosome 11q13.4-->q14.1. Genomics. 1993 Feb; 15(2):463-4.
Score: 0.007
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Molecular biology of somatostatin receptors. Trends Neurosci. 1993 Jan; 16(1):34-8.
Score: 0.007
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Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation. Diabetes. 1992 Nov; 41(11):1436-45.
Score: 0.007
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Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. Biochemistry. 1992 Oct 27; 31(42):10414-20.
Score: 0.007
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Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase. J Biol Chem. 1992 Oct 05; 267(28):20422-8.
Score: 0.007
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Differential expression of somatostatin receptor subtypes in brain. J Neurosci. 1992 Oct; 12(10):3920-34.
Score: 0.007
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In vitro scan for enhancers at the TCF7L2 locus. Diabetologia. 2013 Jan; 56(1):121-5.
Score: 0.007
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An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers. PLoS One. 2012; 7(5):e36501.
Score: 0.007
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Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. Genome Res. 2011 Sep; 21(9):1417-25.
Score: 0.006
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Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Rev Endocr Metab Disord. 2010 Sep; 11(3):205-15.
Score: 0.006
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Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration. Islets. 2010 Jul-Aug; 2(4):261-2.
Score: 0.006
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Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. J Lipid Res. 2010 May; 51(5):907-13.
Score: 0.006
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Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab. 2010 Aug; 21(8):464-72.
Score: 0.006
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Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice. PLoS One. 2010 Jan 18; 5(1):e8749.
Score: 0.006
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In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E403-10.
Score: 0.006
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Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic ß-cells. Islets. 2009 Nov-Dec; 1(3):242-8.
Score: 0.006
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5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun. 2005 May 20; 330(4):1073-9.
Score: 0.004
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Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells. In Vitro Cell Dev Biol Anim. 2005 Jan-Feb; 41(1-2):7-11.
Score: 0.004
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Anti-diabetic effect of ginsenoside Re in ob/ob mice. Biochim Biophys Acta. 2005 Jun 10; 1740(3):319-25.
Score: 0.004
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 04; 279(23):24794-802.
Score: 0.004
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Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. J Biol Chem. 2004 May 14; 279(20):20915-20.
Score: 0.004
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A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism. 2003 May; 52(5):528-34.
Score: 0.004
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Nuclear translocation of SHP and visualization of interaction with HNF-4alpha in living cells. Biochem Biophys Res Commun. 2002 Mar 22; 292(1):8-12.
Score: 0.003
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Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet. 2002 May; 70(5):1096-106.
Score: 0.003
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Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol. 2002 Mar; 26(3):298-305.
Score: 0.003
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Calpains play a role in insulin secretion and action. Diabetes. 2001 Sep; 50(9):2013-20.
Score: 0.003
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Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1. FEBS Lett. 2000 Aug 11; 479(1-2):41-5.
Score: 0.003
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Activation of human somatostatin receptor type 2 causes inhibition of cell growth in transfected HEK293 but not in transfected CHO cells. J Surg Res. 1997 Jul 15; 71(1):13-8.
Score: 0.002
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Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. Neurosurgery. 1996 Sep; 39(3):562-7; discussion 567-8.
Score: 0.002
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Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus. Mol Pharmacol. 1996 Aug; 50(2):230-5.
Score: 0.002
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Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys. J Cereb Blood Flow Metab. 1996 Jul; 16(4):688-97.
Score: 0.002
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Expression of inositol 1,4,5-trisphosphate receptors changes the Ca2+ signal of Xenopus oocytes. Am J Physiol. 1996 Apr; 270(4 Pt 1):C1255-61.
Score: 0.002
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Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochem Biophys Res Commun. 1996 Mar 27; 220(3):532-8.
Score: 0.002
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Activation of a protein tyrosine phosphatase and inactivation of Raf-1 by somatostatin. Biochem J. 1996 Mar 01; 314 ( Pt 2):401-4.
Score: 0.002
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Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat. Pediatr Res. 1996 Mar; 39(3):390-4.
Score: 0.002
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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes. J Biol Chem. 1996 Jan 05; 271(1):390-4.
Score: 0.002
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. Am J Physiol. 1996 Jan; 270(1 Pt 1):E133-40.
Score: 0.002
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Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs. Diabetes. 1995 Aug; 44(8):999-1001.
Score: 0.002
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Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. Genomics. 1995 Jun 10; 27(3):520-5.
Score: 0.002
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Inositol 1,4,5-trisphosphate receptors, secretory granules and secretion in endocrine and neuroendocrine cells. Trends Neurosci. 1995 Apr; 18(4):157-61.
Score: 0.002
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Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1580-4.
Score: 0.002
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Structure and function of ASP, the human homolog of the mouse agouti gene. Hum Mol Genet. 1995 Feb; 4(2):223-30.
Score: 0.002
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A tyrosine phosphatase is associated with the somatostatin receptor. Ciba Found Symp. 1995; 190:187-96; discussion 196-203.
Score: 0.002
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The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells. Neuroscience. 1994 Dec; 63(4):1033-40.
Score: 0.002
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G protein-activated inwardly rectifying potassium channel (GIRK1/KGA) mRNA in adult rat heart and brain by in situ hybridization histochemistry. Mol Cell Neurosci. 1994 Dec; 5(6):515-22.
Score: 0.002
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Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells. J Biol Chem. 1994 Nov 04; 269(44):27167-70.
Score: 0.002
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Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor. J Pharmacol Exp Ther. 1994 Sep; 270(3):1381-6.
Score: 0.002
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Agonists and antagonists bind to different domains of the cloned kappa opioid receptor. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8042-6.
Score: 0.002
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Immunological detection of isoforms of the somatostatin receptor subtype, SSTR2. J Neurochem. 1994 Aug; 63(2):447-55.
Score: 0.002
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Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP. Biochem J. 1994 Jul 01; 301 ( Pt 1):169-75.
Score: 0.002
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Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA. Mol Pharmacol. 1994 May; 45(5):854-60.
Score: 0.002
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Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation. Mol Pharmacol. 1994 Apr; 45(4):587-90.
Score: 0.002
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Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2315-9.
Score: 0.002
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Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistry. Neuroscience. 1994 Mar; 59(1):175-84.
Score: 0.002
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Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol. 1994 Feb; 45(2):330-4.
Score: 0.002
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Localization of somatostatin (SRIF) SSTR-1, SSTR-2 and SSTR-3 receptor mRNA in rat brain by in situ hybridization. Naunyn Schmiedebergs Arch Pharmacol. 1994 Feb; 349(2):145-60.
Score: 0.002
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A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding. J Biol Chem. 1993 Nov 05; 268(31):23055-8.
Score: 0.002
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Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association. Mol Pharmacol. 1993 Aug; 44(2):380-4.
Score: 0.002
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Characterization of cloned somatostatin receptors SSTR4 and SSTR5. Mol Pharmacol. 1993 Aug; 44(2):385-92.
Score: 0.002
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Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation. Mol Endocrinol. 1993 Aug; 7(8):1049-60.
Score: 0.002
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Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion. Diabetes. 1993 Jul; 42(7):948-55.
Score: 0.002
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Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol Pharmacol. 1993 Jun; 43(6):838-44.
Score: 0.002
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Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5. Am J Physiol. 1993 Jun; 264(6 Pt 1):G1169-76.
Score: 0.002
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Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2. J Biol Chem. 1993 May 25; 268(15):10721-7.
Score: 0.002
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Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice. J Biol Chem. 1993 May 05; 268(13):9839-46.
Score: 0.002
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Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. Mol Endocrinol. 1992 Dec; 6(12):2136-42.
Score: 0.002
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Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science. 1992 Jul 31; 257(5070):674-8.
Score: 0.002
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Fructose transporter in human spermatozoa and small intestine is GLUT5. J Biol Chem. 1992 Jul 25; 267(21):14523-6.
Score: 0.002
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Pharmacological properties of two cloned somatostatin receptors. Mol Pharmacol. 1992 Jul; 42(1):28-34.
Score: 0.002
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Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice. J Biol Chem. 1992 Jun 15; 267(17):11673-6.
Score: 0.002