Rima McLeod to Toxoplasma
This is a "connection" page, showing publications Rima McLeod has written about Toxoplasma.
Connection Strength
11.721
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Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites. Front Cell Infect Microbiol. 2020; 10:203.
Score: 0.698
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Seroprevalence of Toxoplasma gondii in domestic pets from metropolitan regions of Panama. Parasite. 2017; 24:9.
Score: 0.557
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New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2016 07 14; 6:29179.
Score: 0.532
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Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics. Clin Infect Dis. 2015 Dec 15; 61(12):1831-4.
Score: 0.504
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Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo. Antimicrob Agents Chemother. 2014; 58(3):1789-92.
Score: 0.446
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Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase. Bioorg Med Chem Lett. 2013 Apr 01; 23(7):2035-43.
Score: 0.420
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Salicylanilide inhibitors of Toxoplasma gondii. J Med Chem. 2012 Oct 11; 55(19):8375-91.
Score: 0.409
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Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14182-7.
Score: 0.406
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Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009). Clin Infect Dis. 2012 Jun; 54(11):1595-605.
Score: 0.396
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Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway. Antimicrob Agents Chemother. 2012 May; 56(5):2666-82.
Score: 0.393
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Oral oocyst-induced mouse model of toxoplasmosis: effect of infection with Toxoplasma gondii strains of different genotypes, dose, and mouse strains (transgenic, out-bred, in-bred) on pathogenesis and mortality. Parasitology. 2012 Jan; 139(1):1-13.
Score: 0.385
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Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-? and reduces parasite burden in HLA-B*0702 mice. Hum Immunol. 2012 Jan; 73(1):1-10.
Score: 0.383
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T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest. PLoS One. 2010 Nov 22; 5(11):e14057.
Score: 0.360
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Towards an immunosense vaccine to prevent toxoplasmosis: protective Toxoplasma gondii epitopes restricted by HLA-A*0201. Vaccine. 2011 Jan 17; 29(4):754-62.
Score: 0.360
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Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase. J Med Chem. 2010 Sep 09; 53(17):6287-300.
Score: 0.355
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Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo. PLoS Negl Trop Dis. 2008 Mar 05; 2(3):e190.
Score: 0.298
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Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo. Antimicrob Agents Chemother. 2005 Aug; 49(8):3463-7.
Score: 0.249
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Delivery of antimicrobials into parasites. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14281-6.
Score: 0.221
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In vitro correlates of Ld-restricted resistance to toxoplasmic encephalitis and their critical dependence on parasite strain. J Immunol. 2002 Jul 15; 169(2):966-73.
Score: 0.202
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Genetic analysis of influences on survival following Toxoplasma gondii infection. Int J Parasitol. 2002 Feb; 32(2):179-85.
Score: 0.196
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High performance of a novel point-of-care blood test for Toxoplasma infection in women from diverse regions of Morocco. Emerg Microbes Infect. 2021 Dec; 10(1):1675-1682.
Score: 0.193
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Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I. Int J Parasitol. 2001 Feb; 31(2):109-13.
Score: 0.183
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Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice. Sci Rep. 2020 10 12; 10(1):16984.
Score: 0.179
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Measurement of the efficacy of vaccines and antimicrobial therapy against infection with Toxoplasma gondii. Int J Parasitol. 2000 Feb; 30(2):149-55.
Score: 0.170
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CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. Front Cell Infect Microbiol. 2018; 8:352.
Score: 0.155
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Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis. Emerg Microbes Infect. 2018 Sep 27; 7(1):165.
Score: 0.155
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Point-of-care testing for Toxoplasma gondii IgG/IgM using Toxoplasma ICT IgG-IgM test with sera from the United States and implications for developing countries. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005670.
Score: 0.142
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Prevalence and genetic characterization of Toxoplasma gondii in free-range chickens from grocery stores and farms in Maryland, Ohio and Massachusetts, USA. Parasitol Res. 2017 May; 116(5):1591-1595.
Score: 0.140
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Congenital toxoplasmosis transmitted from an immunologically competent mother infected before conception. Clin Infect Dis. 1996 Nov; 23(5):1055-60.
Score: 0.136
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Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii. JCI Insight. 2016 09 22; 1(15):e85955.
Score: 0.135
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Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove. Elife. 2016 Jan 29; 5.
Score: 0.129
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Effects of human class I transgenes on Toxoplasma gondii cyst formation. J Immunol. 1994 May 01; 152(9):4537-41.
Score: 0.114
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Effectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic mice. Vaccine. 2014 May 30; 32(26):3243-8.
Score: 0.114
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The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorg Med Chem Lett. 2014 Feb 01; 24(3):911-6.
Score: 0.111
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Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay. Biochemistry. 2013 Dec 23; 52(51):9155-66.
Score: 0.111
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Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii. ChemMedChem. 2013 Jul; 8(7):1138-60.
Score: 0.108
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Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides. Bioorg Med Chem Lett. 2013 Jun 15; 23(12):3551-5.
Score: 0.106
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Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii. Infect Immun. 2012 Dec; 80(12):4298-308.
Score: 0.102
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Severe congenital toxoplasmosis in the United States: clinical and serologic findings in untreated infants. Pediatr Infect Dis J. 2011 Dec; 30(12):1056-61.
Score: 0.097
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Unrecognized ingestion of Toxoplasma gondii oocysts leads to congenital toxoplasmosis and causes epidemics in North America. Clin Infect Dis. 2011 Dec; 53(11):1081-9.
Score: 0.096
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Identification of a sporozoite-specific antigen from Toxoplasma gondii. J Parasitol. 2011 Apr; 97(2):328-37.
Score: 0.092
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Rapid discovery of inhibitors of Toxoplasma gondii using hybrid structure-based computational approach. J Comput Aided Mol Des. 2011 May; 25(5):403-11.
Score: 0.092
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NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells. Infect Immun. 2011 Feb; 79(2):756-66.
Score: 0.090
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Immunogenetics of Toxoplasma gondii informs vaccine design. Trends Parasitol. 2010 Nov; 26(11):550-5.
Score: 0.088
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Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans. Vaccine. 2010 May 21; 28(23):3977-89.
Score: 0.086
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Why prevent, diagnose and treat congenital toxoplasmosis? Mem Inst Oswaldo Cruz. 2009 Mar; 104(2):320-44.
Score: 0.080
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Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. J Neuroinflammation. 2008 Oct 23; 5:48.
Score: 0.078
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Subcellular localization and dynamics of a digalactolipid-like epitope in Toxoplasma gondii. J Lipid Res. 2008 Apr; 49(4):746-62.
Score: 0.074
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Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids. Biochemistry. 2007 Dec 04; 46(48):13882-90.
Score: 0.073
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Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents. Acta Crystallogr D Biol Crystallogr. 2007 Mar; 63(Pt 3):328-38.
Score: 0.069
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Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 01; 62(Pt 6):604-6.
Score: 0.066
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Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. Pediatr Infect Dis J. 2006 Mar; 25(3):270-2.
Score: 0.065
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Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target. Int J Parasitol. 2004 Mar 09; 34(3):297-308.
Score: 0.057
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Toxoplasma gondii tachyzoite-bradyzoite interconversion. Trends Parasitol. 2002 May; 18(5):198-201.
Score: 0.050
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Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase. Proc Natl Acad Sci U S A. 1999 Nov 09; 96(23):13387-92.
Score: 0.042
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The One Health Approach to Toxoplasmosis: Epidemiology, Control, and Prevention Strategies. Ecohealth. 2019 06; 16(2):378-390.
Score: 0.040
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Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies. PLoS Negl Trop Dis. 2018 08; 12(8):e0006536.
Score: 0.038
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The zebrafish, Danio rerio, as a model for Toxoplasma gondii: an initial description of infection in fish. J Fish Dis. 2015 Jul; 38(7):675-9.
Score: 0.031
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Class I MHC genes and CD8+ T cells determine cyst number in Toxoplasma gondii infection. J Immunol. 1990 Nov 15; 145(10):3438-41.
Score: 0.022
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P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages. J Immunol. 2010 Jun 15; 184(12):7040-6.
Score: 0.022
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Longitudinal study of new eye lesions in children with toxoplasmosis who were not treated during the first year of life. Am J Ophthalmol. 2008 Sep; 146(3):375-384.
Score: 0.019