Rima McLeod to Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)
This is a "connection" page, showing publications Rima McLeod has written about Enoyl-(Acyl-Carrier-Protein) Reductase (NADH).
Connection Strength
1.930
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Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides. Bioorg Med Chem Lett. 2013 Jun 15; 23(12):3551-5.
Score: 0.461
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Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase. Bioorg Med Chem Lett. 2013 Apr 01; 23(7):2035-43.
Score: 0.455
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Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase. J Med Chem. 2010 Sep 09; 53(17):6287-300.
Score: 0.385
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The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorg Med Chem Lett. 2014 Feb 01; 24(3):911-6.
Score: 0.121
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Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay. Biochemistry. 2013 Dec 23; 52(51):9155-66.
Score: 0.121
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Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii. ChemMedChem. 2013 Jul; 8(7):1138-60.
Score: 0.116
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Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents. Acta Crystallogr D Biol Crystallogr. 2007 Mar; 63(Pt 3):328-38.
Score: 0.075
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Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 01; 62(Pt 6):604-6.
Score: 0.072
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Delivery of antimicrobials into parasites. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14281-6.
Score: 0.060
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Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I. Int J Parasitol. 2001 Feb; 31(2):109-13.
Score: 0.049
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Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase. Acta Crystallogr D Biol Crystallogr. 2003 Jul; 59(Pt 7):1246-8.
Score: 0.015