Stephen C.MeredithStephen C. Meredith41.78927490000000-87.601250000000002188Meredith, Stephen C.Professorplugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000682Chemicals & Drugs39850.952725AmyloidBiochemistry and Molecular BiologyNeurobiologyAuthorship 118223Authorship 128126Authorship 131693Authorship 153557Authorship 1288011930936544Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong MLDM, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, Wang Y, Snapper SB, Ostrov D, Meredith SC, Miller LW, Turner JRNature medicineIntracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nat Med. 2019 04; 25(4):690-700.Nat Med2019-04-01T00:00:002019Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis.Authorship 1518410Authorship 149322Authorship 156846Authorship 138494Authorship 158774Authorship 129195831022450Zerweck J, Venkata BS, Pittman JM, Srivastava AK, Moore PC, Sachleben JR, Thinakaran G, Meredith SCProtein expression and purificationA versatile method for producing labeled or unlabeled Aß55, Aß40, and other ß-amyloid family peptides. Protein Expr Purif. 2019 10; 162:72-82.Protein Expr Purif2019-04-22T00:00:002019A versatile method for producing labeled or unlabeled Aß55, Aß40, and other ß-amyloid family peptides.Authorship 164623Authorship 165688Authorship 174343Authorship 171597Authorship 185138Authorship 17832Authorship 191953Authorship 190502Authorship 198454Authorship 197224Authorship 209606Authorship 217385Authorship 240694Authorship 177482Authorship 130614731276610Srivastava AK, Pittman JM, Zerweck J, Venkata BS, Moore PC, Sachleben JR, Meredith SCProtein science : a publication of the Protein Societyß-Amyloid aggregation and heterogeneous nucleation. Protein Sci. 2019 09; 28(9):1567-1581.Protein Sci2019-08-06T00:00:002019ß-Amyloid aggregation and heterogeneous nucleation.Authorship 23795Authorship 218712Authorship 269325D010446Chemicals & Drugs2134600.839276Peptide FragmentsAuthorship 26892Authorship 332944Authorship 301294Authorship 279314Authorship 306863Authorship 371455Authorship 346266Authorship 379094Authorship 395104Authorship 291151Authorship 347134Authorship 1338621431672936He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Leisegang M, Meredith SC, Kranz DM, Schreiber HJCI insightMultiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 11 01; 4(21).JCI Insight2019-11-01T00:00:002019Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.D009682PhenomenaProcedures1353180.894682Magnetic Resonance SpectroscopyAuthorship 134340931710741Hawk LML, Pittman JM, Moore PC, Srivastava AK, Zerweck J, Williams JTB, Hawk AJ, Sachleben JR, Meredith SCProtein science : a publication of the Protein Societyß-amyloid model core peptides: Effects of hydrophobes and disulfides. Protein Sci. 2020 02; 29(2):527-541.Protein Sci2019-11-25T00:00:002019ß-amyloid model core peptides: Effects of hydrophobes and disulfides.Authorship 400512Authorship 32203Authorship 43182Authorship 4343111Authorship 306546Authorship 1345951531801912He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Leisegang M, Meredith SC, Kranz DM, Schreiber HJCI insightMultiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 Dec 05; 4(23).JCI Insight2019-12-05T00:00:002019Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.Authorship 324778Authorship 327036Authorship 48593Authorship 378374Authorship 62932Authorship 78792Authorship 83421Authorship 79712Authorship 81982Authorship 90592Authorship 438155Authorship 472165Authorship 484328Authorship 78533Authorship 55363Authorship 50184Authorship 99144Authorship 58332Authorship 5892Authorship 78652Authorship 82181Authorship 85704Authorship 86064Authorship 120884Authorship 138613Authorship 193149Authorship 208293Authorship 2464610Authorship 310844Authorship 417164Authorship 417547Authorship 48583Authorship 50003Authorship 853328652569Fless GM, Furbee J, Snyder ML, Meredith SCBiochemistryLigand-induced conformational change of lipoprotein(a). Biochemistry. 1996 Feb 20; 35(7):2289-98.Biochemistry1996-02-20T00:00:001996Ligand-induced conformational change of lipoprotein(a).8909295Braddock DT, Mercurius KO, Subramanian RM, Dominguez SR, Davies PF, Meredith SCBiochemistryConformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E. Biochemistry. 1996 Nov 05; 35(44):13975-84.Biochemistry1996-11-05T00:00:001996Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E.9034148Dubey P, Hendrickson RC, Meredith SC, Siegel CT, Shabanowitz J, Skipper JC, Engelhard VH, Hunt DF, Schreiber HThe Journal of experimental medicineThe immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68. J Exp Med. 1997 Feb 17; 185(4):695-705.J Exp Med1997-02-17T00:00:001997The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68.9298949Fless GM, Santiago JY, Furbee J, Meredith SCBiochemistrySpecificity of ligand-induced conformational change of lipoprotein(a). Biochemistry. 1997 Sep 23; 36(38):11304-13.Biochemistry1997-09-23T00:00:001997Specificity of ligand-induced conformational change of lipoprotein(a).9672849Dubey P, Meredith SC, Siegel CT, Schreiber HJournal of immunotherapy (Hagerstown, Md. : 1997)Tumor cells induce cytolytic T cells to a single immunodominant mutant peptide. J Immunother. 1998 Jul; 21(4):277-82.J Immunother1998-07-01T00:00:001998Tumor cells induce cytolytic T cells to a single immunodominant mutant peptide.10526337Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Lynn DG, Thinakaran G, Meredith SC, Sisodia SSNature neuroscienceFurin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci. 1999 Nov; 2(11):984-8.Nat Neurosci1999-11-01T00:00:001999Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia.10940223Lynn DG, Meredith SCJournal of structural biologyReview: model peptides and the physicochemical approach to beta-amyloids. J Struct Biol. 2000 Jun; 130(2-3):153-73.J Struct Biol2000-06-01T00:00:002000Review: model peptides and the physicochemical approach to beta-amyloids.10727245Benzinger TL, Gregory DM, Burkoth TS, Miller-Auer H, Lynn DG, Botto RE, Meredith SCBiochemistryTwo-dimensional structure of beta-amyloid(10-35) fibrils. Biochemistry. 2000 Mar 28; 39(12):3491-9.Biochemistry2000-03-28T00:00:002000Two-dimensional structure of beta-amyloid(10-35) fibrils.11444969Gordon DJ, Sciarretta KL, Meredith SCBiochemistryInhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry. 2001 Jul 27; 40(28):8237-45.Biochemistry2001-07-27T00:00:002001Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues.11193182Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Thinakaran G, Lynn DG, Meredith SC, Sisodia SSAnnals of the New York Academy of SciencesFamilial British dementia: expression and metabolism of BRI. Ann N Y Acad Sci. 2000; 920:93-9.Ann N Y Acad Sci2000-01-01T00:00:002000Familial British dementia: expression and metabolism of BRI.11390461Weijzen S, Meredith SC, Velders MP, Elmishad AG, Schreiber H, Kast WMJournal of immunology (Baltimore, Md. : 1950)Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide. J Immunol. 2001 Jun 15; 166(12):7151-7.J Immunol2001-06-15T00:00:002001Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide.9811813Benzinger TL, Gregory DM, Burkoth TS, Miller-Auer H, Lynn DG, Botto RE, Meredith SCProceedings of the National Academy of Sciences of the United States of AmericaPropagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13407-12.Proc Natl Acad Sci U S A1998-11-10T00:00:001998Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register.11489948Beck-Engeser GB, Monach PA, Mumberg D, Yang F, Wanderling S, Schreiber K, Espinosa R, Le Beau MM, Meredith SC, Schreiber HThe Journal of experimental medicinePoint mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens. J Exp Med. 2001 Aug 06; 194(3):285-300.J Exp Med2001-08-06T00:00:002001Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens.10191300Dominguez SR, Miller-Auer H, Reardon CA, Meredith SCJournal of lipid researchPeptide model of a highly conserved, N-terminal domain of apolipoprotein E is able to modulate lipoprotein binding to a member of the class A scavenger receptor family. J Lipid Res. 1999 Apr; 40(4):753-63.J Lipid Res1999-04-01T00:00:001999Peptide model of a highly conserved, N-terminal domain of apolipoprotein E is able to modulate lipoprotein binding to a member of the class A scavenger receptor family.9748329Benzinger TL, Braddock DT, Dominguez SR, Burkoth TS, Miller-Auer H, Subramanian RM, Fless GM, Jones DN, Lynn DG, Meredith SCBiochemistryStructure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E. Biochemistry. 1998 Sep 22; 37(38):13222-9.Biochemistry1998-09-22T00:00:001998Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E.10023844Gregory DM, Benzinger TL, Burkoth TS, Miller-Auer H, Lynn DG, Meredith SC, Botto RESolid state nuclear magnetic resonanceDipolar recoupling NMR of biomolecular self-assemblies: determining inter- and intrastrand distances in fibrilized Alzheimer's beta-amyloid peptide. Solid State Nucl Magn Reson. 1998 Dec; 13(3):149-66.Solid State Nucl Magn Reson1998-12-01T00:00:001998Dipolar recoupling NMR of biomolecular self-assemblies: determining inter- and intrastrand distances in fibrilized Alzheimer's beta-amyloid peptide.1667458Teegarden D, Meredith SC, Sitrin MDAnalytical biochemistryDetermination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads. Anal Biochem. 1991 Dec; 199(2):293-9.Anal Biochem1991-12-01T00:00:001991Determination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads.10839809Siegel CT, Schreiber K, Meredith SC, Beck-Engeser GB, Lancki DW, Lazarski CA, Fu YX, Rowley DA, Schreiber HThe Journal of experimental medicineEnhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein. J Exp Med. 2000 Jun 05; 191(11):1945-56.J Exp Med2000-06-05T00:00:002000Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein.12124300Balbach JJ, Petkova AT, Oyler NA, Antzutkin ON, Gordon DJ, Meredith SC, Tycko RBiophysical journalSupramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance. Biophys J. 2002 Aug; 83(2):1205-16.Biophys J2002-08-01T00:00:002002Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance.12525175Gordon DJ, Meredith SCBiochemistryProbing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. Biochemistry. 2003 Jan 21; 42(2):475-85.Biochemistry2003-01-21T00:00:002003Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.11744719Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GSThe Journal of biological chemistryApolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. J Biol Chem. 2002 Mar 22; 277(12):9645-54.J Biol Chem2001-12-14T00:00:002001Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution.12081625Gordon DJ, Tappe R, Meredith SCThe journal of peptide research : official journal of the American Peptide SocietyDesign and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis. J Pept Res. 2002 Jul; 60(1):37-55.J Pept Res2002-07-01T00:00:002002Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis.Authorship 142910633356812Dougherty U, Mustafi R, Zhu H, Zhu X, Deb D, Meredith SC, Ayaloglu-Butun F, Fletcher M, Sanchez A, Pekow J, Deng Z, Amini N, Konda VJ, Rao VL, Sakuraba A, Kwesi A, Kupfer SS, Fichera A, Joseph L, Hart J, He F, He TC, West-Szymanski D, Li YC, Bissonnette MEpigeneticsUpregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer. Epigenetics. 2021 12; 16(12):1317-1334.Epigenetics2020-12-28T00:00:002020Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer.Authorship 143211933420184Scherpelz KP, Wang S, Pytel P, Madhurapantula RS, Srivastava AK, Sachleben JR, Orgel J, Ishii Y, Meredith SCScientific reportsAtomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils. Sci Rep. 2021 01 08; 11(1):247.Sci Rep2021-01-08T00:00:002021Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils.11705394Morgan DM, Lynn DG, Miller-Auer H, Meredith SCBiochemistryA designed Zn2+-binding amphiphilic polypeptide: energetic consequences of pi-helicity. Biochemistry. 2001 Nov 20; 40(46):14020-9.Biochemistry2001-11-20T00:00:002001A designed Zn2+-binding amphiphilic polypeptide: energetic consequences of pi-helicity.14695285Gordon DJ, Balbach JJ, Tycko R, Meredith SCBiophysical journalIncreasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel. Biophys J. 2004 Jan; 86(1 Pt 1):428-34.Biophys J2004-01-01T00:00:002004Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel.1943091Kadowaki MH, Singh TM, Zarins CK, Glagov S, Meredith SCThe Journal of surgical researchThe effect of hypercholesterolemia on early atherosclerotic lesions initiated by fibrinopeptide B. J Surg Res. 1991 Dec; 51(6):524-8.J Surg Res1991-12-01T00:00:001991The effect of hypercholesterolemia on early atherosclerotic lesions initiated by fibrinopeptide B.15077191Schreiber K, Cannon RE, Karrison T, Beck-Engeser G, Huo D, Tennant RW, Jensen H, Kast WM, Krausz T, Meredith SC, Chen L, Schreiber HOncogeneStrong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene. 2004 May 13; 23(22):3972-9.Oncogene2004-05-13T00:00:002004Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors.2064600Tonsgard JH, Meredith SCThe Biochemical journalCharacterization of the binding sites for dicarboxylic acids on bovine serum albumin. Biochem J. 1991 Jun 15; 276 ( Pt 3):569-75.Biochem J1991-06-15T00:00:001991Characterization of the binding sites for dicarboxylic acids on bovine serum albumin.Ben May Department of Cancer Research17046402Sciarretta KL, Gordon DJ, Meredith SCMethods in enzymologyPeptide-based inhibitors of amyloid assembly. Methods Enzymol. 2006; 413:273-312.Methods Enzymol2006-01-01T00:00:002006Peptide-based inhibitors of amyloid assembly.17945257Darnell G, Orgel JP, Pahl R, Meredith SCJournal of molecular biologyFlanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure. J Mol Biol. 2007 Nov 30; 374(3):688-704.J Mol Biol2007-09-14T00:00:002007Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.17177369Lazar KL, Kurutz JW, Tycko R, Meredith SCJournal of the American Chemical SocietyEncapsulation and NMR on an aggregating peptide before fibrillogenesis. J Am Chem Soc. 2006 Dec 27; 128(51):16460-1.J Am Chem Soc2006-12-27T00:00:002006Encapsulation and NMR on an aggregating peptide before fibrillogenesis.2308832Matsushima T, Getz GS, Meredith SCNucleic acids researchPrimary structure of guinea pig apolipoprotein E. Nucleic Acids Res. 1990 Jan 11; 18(1):202.Nucleic Acids Res1990-01-11T00:00:001990Primary structure of guinea pig apolipoprotein E.15835889Sciarretta KL, Gordon DJ, Petkova AT, Tycko R, Meredith SCBiochemistryAbeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry. 2005 Apr 26; 44(16):6003-14.Biochemistry2005-04-26T00:00:002005Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid.19376973Paravastu AK, Qahwash I, Leapman RD, Meredith SC, Tycko RProceedings of the National Academy of Sciences of the United States of AmericaSeeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7443-8.Proc Natl Acad Sci U S A2009-04-17T00:00:002009Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure.19358576Tycko R, Sciarretta KL, Orgel JP, Meredith SCBiochemistryEvidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils. Biochemistry. 2009 Jul 07; 48(26):6072-84.Biochemistry2009-07-07T00:00:002009Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.20583779Lanning JD, Hawk AJ, Derryberry J, Meredith SCBiochemistryChaperone-like N-methyl peptide inhibitors of polyglutamine aggregation. Biochemistry. 2010 Aug 24; 49(33):7108-18.Biochemistry2010-08-24T00:00:002010Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation.16533927Meredith SCAnnals of the New York Academy of SciencesProtein denaturation and aggregation: Cellular responses to denatured and aggregated proteins. Ann N Y Acad Sci. 2005 Dec; 1066:181-221.Ann N Y Acad Sci2005-12-01T00:00:002005Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.20593467Bockhorn JJ, Lazar KL, Gasser AJ, Luther LM, Qahwash IM, Chopra N, Meredith SCBiopolymersNovel semisynthetic method for generating full length beta-amyloid peptides. Biopolymers. 2010; 94(4):511-20.Biopolymers2010-01-01T00:00:002010Novel semisynthetic method for generating full length beta-amyloid peptides.16878983Sciarretta KL, Boire A, Gordon DJ, Meredith SCBiochemistrySpatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids. Biochemistry. 2006 Aug 08; 45(31):9485-95.Biochemistry2006-08-08T00:00:002006Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids.19843462Darnell GD, Derryberry J, Kurutz JW, Meredith SCBiophysical journalMechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect. Biophys J. 2009 Oct 21; 97(8):2295-305.Biophys J2009-10-21T00:00:002009Mechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect.17038624Schietinger A, Philip M, Yoshida BA, Azadi P, Liu H, Meredith SC, Schreiber HScience (New York, N.Y.)A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science. 2006 Oct 13; 314(5797):304-8.Science2006-10-13T00:00:002006A mutant chaperone converts a wild-type protein into a tumor-specific antigen.21167756Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJImmunityThe 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity. 2010 Dec 14; 33(6):853-62.Immunity2010-12-14T00:00:002010The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation.17693400Qahwash IM, Boire A, Lanning J, Krausz T, Pytel P, Meredith SCThe Journal of biological chemistrySite-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity. J Biol Chem. 2007 Dec 21; 282(51):36987-97.J Biol Chem2007-08-09T00:00:002007Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity.21291268Cloe AL, Orgel JP, Sachleben JR, Tycko R, Meredith SCBiochemistryThe Japanese mutant Aß (?E22-Aß(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aß(1-40) into atypical fibrils by ?E22-Aß(1-39). Biochemistry. 2011 Mar 29; 50(12):2026-39.Biochemistry2011-02-24T00:00:002011The Japanese mutant Aß (?E22-Aß(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aß(1-40) into atypical fibrils by ?E22-Aß(1-39).Authorship 1467001034029056Pittman JM, Srivastava AK, Boughter CT, Venkata BS, Zerweck J, Moore PC, Smok I, Tonelli M, Sachleben JR, Meredith SCBiochemistryNanodroplet Oligomers (NanDOs) of Aß40. Biochemistry. 2021 09 14; 60(36):2691-2703.Biochemistry2021-05-24T00:00:002021Nanodroplet Oligomers (NanDOs) of Aß40.22585572Distler MG, Plant LD, Sokoloff G, Hawk AJ, Aneas I, Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AAThe Journal of clinical investigationGlyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest. 2012 Jun; 122(6):2306-15.J Clin Invest2012-05-15T00:00:002012Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.22215668Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJThe Journal of biological chemistry?d T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion. J Biol Chem. 2012 Feb 17; 287(8):6035-43.J Biol Chem2012-01-03T00:00:002012?d T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion.3525532Reddy MN, Maraganore JM, Meredith SC, Heinrikson RL, Kézdy FJThe Journal of biological chemistryIsolation of an active-site peptide of lipoprotein lipase from bovine milk and determination of its amino acid sequence. J Biol Chem. 1986 Jul 25; 261(21):9678-83.J Biol Chem1986-07-25T00:00:001986Isolation of an active-site peptide of lipoprotein lipase from bovine milk and determination of its amino acid sequence.646580Sitrin M, Meredith S, Rosenberg IHArchives of internal medicineVitamin D deficiency and bone disease in gastrointestinal disorders. Arch Intern Med. 1978 May 15; 138 Spec No:886-8.Arch Intern Med1978-05-15T00:00:001978Vitamin D deficiency and bone disease in gastrointestinal disorders.6806381Retzinger GS, Meredith SC, Hunter RL, Takayama K, Kézdy FJJournal of immunology (Baltimore, Md. : 1950)Identification of the physiologically active state of the mycobacterial glycolipid trehalose 6,6'-dimycolate and the role of fibrinogen in the biologic activities of trehalose 6,6'-dimycolate monolayers. J Immunol. 1982 Aug; 129(2):735-44.J Immunol1982-08-01T00:00:001982Identification of the physiologically active state of the mycobacterial glycolipid trehalose 6,6'-dimycolate and the role of fibrinogen in the biologic activities of trehalose 6,6'-dimycolate monolayers.16171382Lazar KL, Miller-Auer H, Getz GS, Orgel JP, Meredith SCBiochemistryHelix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure. Biochemistry. 2005 Sep 27; 44(38):12681-9.Biochemistry2005-09-27T00:00:002005Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure.Authorship 147585734241272Natesh SR, Hummels AR, Sachleben JR, Sosnick TR, Freed KF, Douglas JF, Meredith SC, Haddadian EJThe Journal of chemical physicsMolecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils. J Chem Phys. 2021 Jun 21; 154(23):235102.J Chem Phys2021-06-21T00:00:002021Molecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils.20016493Liebman SW, Meredith SCNature chemical biologyProtein folding: sticky N17 speeds huntingtin pile-up. Nat Chem Biol. 2010 Jan; 6(1):7-8.Nat Chem Biol2010-01-01T00:00:002010Protein folding: sticky N17 speeds huntingtin pile-up.Authorship 148283734308630Wickramasinghe A, Xiao Y, Kobayashi N, Wang S, Scherpelz KP, Yamazaki T, Meredith SC, Ishii YJournal of the American Chemical SocietySensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-ß Fibrils. J Am Chem Soc. 2021 08 04; 143(30):11462-11472.J Am Chem Soc2021-07-26T00:00:002021Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-ß Fibrils.3119588Gordon ED, Mora R, Meredith SC, Lee C, Lindquist SLThe Journal of biological chemistryEukaryotic initiation factor 4D, the hypusine-containing protein, is conserved among eukaryotes. J Biol Chem. 1987 Dec 05; 262(34):16585-9.J Biol Chem1987-12-05T00:00:001987Eukaryotic initiation factor 4D, the hypusine-containing protein, is conserved among eukaryotes.3183053Tonsgard JH, Mendelson SA, Meredith SCThe Journal of clinical investigationBinding of straight-chain saturated dicarboxylic acids to albumin. J Clin Invest. 1988 Nov; 82(5):1567-73.J Clin Invest1988-11-01T00:00:001988Binding of straight-chain saturated dicarboxylic acids to albumin.7600302Monach PA, Meredith SC, Siegel CT, Schreiber HImmunityA unique tumor antigen produced by a single amino acid substitution. Immunity. 1995 Jan; 2(1):45-59.Immunity1995-01-01T00:00:001995A unique tumor antigen produced by a single amino acid substitution.3119589Gordon ED, Mora R, Meredith SC, Lindquist SLThe Journal of biological chemistryHypusine formation in eukaryotic initiation factor 4D is not reversed when rates or specificity of protein synthesis is altered. J Biol Chem. 1987 Dec 05; 262(34):16590-5.J Biol Chem1987-12-05T00:00:001987Hypusine formation in eukaryotic initiation factor 4D is not reversed when rates or specificity of protein synthesis is altered.3759983Kawooya JK, Meredith SC, Wells MA, Kézdy FJ, Law JHThe Journal of biological chemistryPhysical and surface properties of insect apolipophorin III. J Biol Chem. 1986 Oct 15; 261(29):13588-91.J Biol Chem1986-10-15T00:00:001986Physical and surface properties of insect apolipophorin III.6711815Heinrikson RL, Meredith SCAnalytical biochemistryAmino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate. Anal Biochem. 1984 Jan; 136(1):65-74.Anal Biochem1984-01-01T00:00:001984Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate.6998607Meredith SC, Rosenberg IHClinics in endocrinology and metabolismGastrointestinal-hepatic disorders and osteomalacia. Clin Endocrinol Metab. 1980 Mar; 9(1):131-50.Clin Endocrinol Metab1980-03-01T00:00:001980Gastrointestinal-hepatic disorders and osteomalacia.7380180Sitrin MD, Rosenberg IH, Chawla K, Meredith S, Sellin J, Rabb JM, Coe F, Kirsner JB, Kraft SCGastroenterologyNutritional and metabolic complications in a patient with Crohn's disease and ileal resection. Gastroenterology. 1980 May; 78(5 Pt 1):1069-79.Gastroenterology1980-05-01T00:00:001980Nutritional and metabolic complications in a patient with Crohn's disease and ileal resection.7412260Schlenker JD, Indresano AT, Raine T, Meredith SC, Robson MCThe Journal of surgical researchA new flap in the dog containing a vascularized rib graft--the latissimus dorsi myoosteocutaneous flap. J Surg Res. 1980 Aug; 29(2):172-83.J Surg Res1980-08-01T00:00:001980A new flap in the dog containing a vascularized rib graft--the latissimus dorsi myoosteocutaneous flap.7351289Reed JS, Meredith SC, Nemchausky BA, Rosenberg IH, Boyer JLGastroenterologyBone disease in primary biliary cirrhosis: reversal of osteomalacia with oral 25-hydroxyvitamin D. Gastroenterology. 1980 Mar; 78(3):512-7.Gastroenterology1980-03-01T00:00:001980Bone disease in primary biliary cirrhosis: reversal of osteomalacia with oral 25-hydroxyvitamin D.7918459Luo P, Braddock DT, Subramanian RM, Meredith SC, Lynn DGBiochemistryStructural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation. Biochemistry. 1994 Oct 18; 33(41):12367-77.Biochemistry1994-10-18T00:00:001994Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation.6982188Driscoll RH, Meredith SC, Sitrin M, Rosenberg IHGastroenterologyVitamin D deficiency and bone disease in patients with Crohn's disease. Gastroenterology. 1982 Dec; 83(6):1252-8.Gastroenterology1982-12-01T00:00:001982Vitamin D deficiency and bone disease in patients with Crohn's disease.4083474Retzinger GS, Meredith SC, Lau SH, Kaiser ET, Kézdy FJAnalytical biochemistryA method for probing the affinity of peptides for amphiphilic surfaces. Anal Biochem. 1985 Oct; 150(1):131-40.Anal Biochem1985-10-01T00:00:001985A method for probing the affinity of peptides for amphiphilic surfaces.19159293Chopra N, Gan W, Schreiber H, Kurutz JW, Meredith SCBioconjugate chemistryVersatile cyclic templates for assembly of axially oriented ligands. Bioconjug Chem. 2009 Feb; 20(2):231-40.Bioconjug Chem2009-02-01T00:00:002009Versatile cyclic templates for assembly of axially oriented ligands.8594977Barbee KA, Morrow JA, Meredith SCAnalytical biochemistryDeconvolution of gel filtration chromatographs of human plasma lipoproteins. Anal Biochem. 1995 Nov 01; 231(2):301-8.Anal Biochem1995-11-01T00:00:001995Deconvolution of gel filtration chromatographs of human plasma lipoproteins.2840181Bolt MJ, Meredith SC, Rosenberg IHCalcified tissue internationalSuppression of rat hepatic vitamin D-25-hydroxylase by cholecalciferol, but not by 25-hydroxy- or 1,25-dihydroxymetabolites. Calcif Tissue Int. 1988 Apr; 42(4):273-8.Calcif Tissue Int1988-04-01T00:00:001988Suppression of rat hepatic vitamin D-25-hydroxylase by cholecalciferol, but not by 25-hydroxy- or 1,25-dihydroxymetabolites.3189784Mora R, Berndt KD, Tsai H, Meredith SCAnalytical biochemistryQuantitation of aspartate and glutamate in HPLC analysis of phenylthiocarbamyl amino acids. Anal Biochem. 1988 Aug 01; 172(2):368-76.Anal Biochem1988-08-01T00:00:001988Quantitation of aspartate and glutamate in HPLC analysis of phenylthiocarbamyl amino acids.6706300Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IHHepatology (Baltimore, Md.)Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease. Hepatology. 1984 Mar-Apr; 4(2):261-5.Hepatology1984-03-01T00:00:001984Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease.6724254Sellin JH, Meredith SC, Kelly S, Schneir H, Rosenberg IHGastroenterologyProspective evaluation of metabolic bone disease after jejunoileal bypass. Gastroenterology. 1984 Jul; 87(1):123-9.Gastroenterology1984-07-01T00:00:001984Prospective evaluation of metabolic bone disease after jejunoileal bypass.7103052Meredith SC, Nathans GRAnalytical biochemistryGel permeation chromatography of asymmetric proteins. Anal Biochem. 1982 Apr; 121(2):234-43.Anal Biochem1982-04-01T00:00:001982Gel permeation chromatography of asymmetric proteins.9304820Steck TL, Chiaraviglio L, Meredith SThe Journal of eukaryotic microbiologyOsmotic homeostasis in Dictyostelium discoideum: excretion of amino acids and ingested solutes. J Eukaryot Microbiol. 1997 Sep-Oct; 44(5):503-10.J Eukaryot Microbiol1997-09-01T00:00:001997Osmotic homeostasis in Dictyostelium discoideum: excretion of amino acids and ingested solutes.10490983Davis DP, Khurana R, Meredith S, Stevens FJ, Argon YJournal of immunology (Baltimore, Md. : 1950)Mapping the major interaction between binding protein and Ig light chains to sites within the variable domain. J Immunol. 1999 Oct 01; 163(7):3842-50.J Immunol1999-10-01T00:00:001999Mapping the major interaction between binding protein and Ig light chains to sites within the variable domain.12479820Spiotto MT, Yu P, Rowley DA, Nishimura MI, Meredith SC, Gajewski TF, Fu YX, Schreiber HImmunityIncreasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 2002 Dec; 17(6):737-47.Immunity2002-12-01T00:00:002002Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.17613531Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJThe Journal of biological chemistryStructure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. J Biol Chem. 2007 Aug 31; 282(35):25453-63.J Biol Chem2007-07-05T00:00:002007Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.18367205Makabe K, Biancalana M, Yan S, Tereshko V, Gawlak G, Miller-Auer H, Meredith SC, Koide SJournal of molecular biologyHigh-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold. J Mol Biol. 2008 Apr 25; 378(2):459-67.J Mol Biol2008-03-04T00:00:002008High-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold.18385132Carnemolla R, Ren X, Biswas TK, Meredith SC, Reardon CA, Wang J, Getz GSThe Journal of biological chemistryThe specific amino acid sequence between helices 7 and 8 influences the binding specificity of human apolipoprotein A-I for high density lipoprotein (HDL) subclasses: a potential for HDL preferential generation. J Biol Chem. 2008 Jun 06; 283(23):15779-88.J Biol Chem2008-04-01T00:00:002008The specific amino acid sequence between helices 7 and 8 influences the binding specificity of human apolipoprotein A-I for high density lipoprotein (HDL) subclasses: a potential for HDL preferential generation.D016229Chemicals & Drugs472030.877587Amyloid beta-PeptidesAuthorship 1585911235969745Srivastava AK, Venkata BS, Sweat YY, Rizzo HR, Jean-François L, Zuo L, Kurgan KW, Moore P, Shashikanth N, Smok I, Sachleben JR, Turner JR, Meredith SCProceedings of the National Academy of Sciences of the United States of AmericaSerine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119.Proc Natl Acad Sci U S A2022-08-15T00:00:002022Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle.https://savagelab.uchicago.eduSavage Lab Sitehttp://voices.uchicago.edu/drsisodialab/Sisodia Labhttp://sosnick.uchicago.edu/Sosnick lab websitehttp://ejadamslab.bsd.uchicago.eduLab websitehttp://voices.uchicago.edu/wtang-lab/Wei-Jen Tang laboratory siteChangUCanSpareUChiAdamsLab, @ErinJAdamsD010455Chemicals & Drugs2456390.756113PeptidesMedicinePathologyUniversity of ChicagoPeterPytelx3JwH6QZOfnamXNnYUHhvWD+6g==Peter Pytel41.78927490000000-87.601250000000001091Pytel, PeterProfessorPeterSavagePeter Savage41.78927490000000-87.601250000000001760Savage, PeterAssociate ProfessorHansSchreiberHans Schreiber41.78927490000000-87.601250000000001921Schreiber, HansProfessor7.674020.00176283548research areas0.8566050.0029795526coauthor of90.48136.1608660similar to11104selected publicationsErin J.Adams0mhoD6AYCszMknJtY0fp/Cv/+94=Erin J. Adams41.78927490000000-87.601250000000002348Adams, Erin J.ProfessorAnthonyChangAnthony Chang41.78927490000000-87.601250000000002601Chang, AnthonyProfessorJames HowardTonsgardJames Howard Tonsgard41.78927490000000-87.60125000000000420Tonsgard, James HowardClinical Associate ProfessorSangram S.SisodiaxHF6ArIaHeX5hHlsaUXv9Gq0+s+oSangram S. Sisodia41.78927490000000-87.60125000000000510Sisodia, Sangram S.ProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorTae-JinKimTae-Jin Kim41.78927490000000-87.60125000000000595Kim, Tae-JinPostdoctoral ScholarGodfreyGetzGodfrey S. Getz41.78927490000000-87.60125000000000725Getz, GodfreyEmeritus/Emerita, ProfessorTobin R.Sosnickw3B6BLIbEO/5hHlsaUXv9Gq0+s+oTobin R. Sosnick41.78927490000000-87.60125000000000744Sosnick, Tobin R.ProfessorJeromeTaxyJerome Taxy41.78927490000000-87.60125000000000836Taxy, JeromeClinical ProfessorVeraTesicVera Tesic41.78927490000000-87.60125000000000869Tesic, Vera0000-0003-0004-8445ProfessorWei-JenTangWei-Jen Tang41.78927490000000-87.60125000000000957Tang, Wei-JenProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Postdoctoral ScholarPostdoctoral Scholartrue1ProfessorProfessortrue1Clinical ProfessorClinical Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Clinical Associate ProfessorClinical Associate ProfessorAuthorship 653203Authorship 668883Authorship 725205Authorship 724202Authorship 73853525336651Yue MM, Lv K, Meredith SC, Martindale JL, Gorospe M, Schuger LThe Journal of biological chemistryNovel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3). J Biol Chem. 2014 Dec 05; 289(49):33971-83.J Biol Chem2014-10-21T00:00:002014Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3).24034249Lu JX, Qiang W, Yau WM, Schwieters CD, Meredith SC, Tycko RCellMolecular structure of ß-amyloid fibrils in Alzheimer's disease brain tissue. Cell. 2013 Sep 12; 154(6):1257-68.Cell2013-09-12T00:00:002013Molecular structure of ß-amyloid fibrils in Alzheimer's disease brain tissue.24364734Dominguez L, Meredith SC, Straub JE, Thirumalai DJournal of the American Chemical SocietyTransmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature. J Am Chem Soc. 2014 Jan 22; 136(3):854-7.J Am Chem Soc2014-01-08T00:00:002014Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature.24926593Dominguez L, Foster L, Meredith SC, Straub JE, Thirumalai DJournal of the American Chemical SocietyStructural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection. J Am Chem Soc. 2014 Jul 09; 136(27):9619-26.J Am Chem Soc2014-06-30T00:00:002014Structural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection.24931469King JV, Liang WG, Scherpelz KP, Schilling AB, Meredith SC, Tang WJStructure (London, England : 1993)Molecular basis of substrate recognition and degradation by human presequence protease. Structure. 2014 Jul 08; 22(7):996-1007.Structure2014-06-12T00:00:002014Molecular basis of substrate recognition and degradation by human presequence protease.Authorship 80600426070092Do TD, Chamas A, Zheng X, Barnes A, Chang D, Veldstra T, Takhar H, Dressler N, Trapp B, Miller K, McMahon A, Meredith SC, Shea JE, Lazar Cantrell K, Bowers MTBiochemistryElucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation. Biochemistry. 2015 Jul 07; 54(26):4050-62.Biochemistry2015-06-24T00:00:002015Elucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation.Pediatrics-NeurologyAuthorship 83667426453221Scherpelz KP, Lu JX, Tycko R, Meredith SCMethods in molecular biology (Clifton, N.J.)Preparation of Amyloid Fibrils Seeded from Brain and Meninges. Methods Mol Biol. 2016; 1345:299-312.Methods Mol Biol2016-01-01T00:00:002016Preparation of Amyloid Fibrils Seeded from Brain and Meninges.Chicago60637ILAuthorship 86224726755823Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJJournal of immunology (Baltimore, Md. : 1950)Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42.J Immunol2016-01-11T00:00:002016Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers.Authorship 89651327114096Johnson EC, Lanning JD, Meredith SCJournal of peptide science : an official publication of the European Peptide SocietyPeptide backbone modification in the bend region of amyloid-ß inhibits fibrillogenesis but not oligomer formation. J Pept Sci. 2016 May; 22(5):368-73.J Pept Sci2016-04-26T00:00:002016Peptide backbone modification in the bend region of amyloid-ß inhibits fibrillogenesis but not oligomer formation.Authorship 501353Authorship 513103Authorship 519962Authorship 533359Authorship 621668Authorship 5178611064352Berns MW, Rattner JB, Meredith S, Witter MAnnals of the New York Academy of SciencesCurrent laser microirradiation studies. Ann N Y Acad Sci. 1976 Jan 30; 267:160-75.Ann N Y Acad Sci1976-01-30T00:00:001976Current laser microirradiation studies.7263645Retzinger GS, Meredith SC, Takayama K, Hunter RL, Kézdy FJThe Journal of biological chemistryThe role of surface in the biological activities of trehalose 6,6'-dimycolate. Surface properties and development of a model system. J Biol Chem. 1981 Aug 10; 256(15):8208-16.J Biol Chem1981-08-10T00:00:001981The role of surface in the biological activities of trehalose 6,6'-dimycolate. Surface properties and development of a model system.6480578Meredith SCThe Journal of biological chemistryThe determination of molecular weight of proteins by gel permeation chromatography in organic solvents. J Biol Chem. 1984 Oct 10; 259(19):11682-5.J Biol Chem1984-10-10T00:00:001984The determination of molecular weight of proteins by gel permeation chromatography in organic solvents.9815796Shawver LK, Schwartz DP, Mann E, Chen H, Tsai J, Chu L, Taylorson L, Longhi M, Meredith S, Germain L, Jacobs JS, Tang C, Ullrich A, Berens ME, Hersh E, McMahon G, Hirth KP, Powell TJClinical cancer research : an official journal of the American Association for Cancer ResearchInhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide. Clin Cancer Res. 1997 Jul; 3(7):1167-77.Clin Cancer Res1997-07-01T00:00:001997Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.23597565Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, Kranz DM, Meredith SC, Rowley DA, Schreiber HCancer cellRelapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 2013 Apr 15; 23(4):516-26.Cancer Cell2013-04-15T00:00:002013Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.3932338Borensztajn J, Kotlar TJ, Meredith SCThe Journal of biological chemistryFractionation of chylomicrons by heparin-sepharose chromatography. Characterization of two heparin-binding proteins. J Biol Chem. 1985 Oct 25; 260(24):13047-52.J Biol Chem1985-10-25T00:00:001985Fractionation of chylomicrons by heparin-sepharose chromatography. Characterization of two heparin-binding proteins.Authorship 99393327615730Poellmann MJ, Sosnick TR, Meredith SC, Lee RCMacromolecular bioscienceThe Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme. Macromol Biosci. 2017 02; 17(2).Macromol Biosci2016-09-12T00:00:002016The Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme.