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Connection

Kulandaivelu Vetrivel to Aspartic Acid Endopeptidases

This is a "connection" page, showing publications Kulandaivelu Vetrivel has written about Aspartic Acid Endopeptidases.
  1. Loss of cleavage at ß'-site contributes to apparent increase in ß-amyloid peptide (Aß) secretion by ß-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein. J Biol Chem. 2011 Jul 22; 286(29):26166-77.
    View in: PubMed
    Score: 0.343
  2. Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. J Biol Chem. 2009 Feb 06; 284(6):3793-803.
    View in: PubMed
    Score: 0.289
  3. Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J Biol Chem. 2005 Jul 08; 280(27):25892-900.
    View in: PubMed
    Score: 0.225
  4. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9665-E9674.
    View in: PubMed
    Score: 0.134
  5. Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase. Mol Neurodegener. 2014 Jan 04; 9:1.
    View in: PubMed
    Score: 0.103
  6. A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aß production. Cell Rep. 2013 Dec 26; 5(6):1552-63.
    View in: PubMed
    Score: 0.103
  7. Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments. Neurology. 2006 Jan 24; 66(2 Suppl 1):S69-73.
    View in: PubMed
    Score: 0.059
  8. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem. 2004 Oct 22; 279(43):44945-54.
    View in: PubMed
    Score: 0.054
  9. S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. J Biol Chem. 2009 Jan 16; 284(3):1373-84.
    View in: PubMed
    Score: 0.018
  10. Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts. Nat Clin Pract Neurol. 2007 Jul; 3(7):374-82.
    View in: PubMed
    Score: 0.016
  11. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. J Biol Chem. 2005 Apr 29; 280(17):17020-6.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.