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Connection

Mahesh P. Gupta to Cardiomegaly

This is a "connection" page, showing publications Mahesh P. Gupta has written about Cardiomegaly.
Connection Strength

3.306
  1. Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nat Commun. 2015 Apr 14; 6:6656.
    View in: PubMed
    Score: 0.482
  2. Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. Circ Res. 2014 Jan 17; 114(2):368-78.
    View in: PubMed
    Score: 0.443
  3. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. J Biol Chem. 2013 Apr 19; 288(16):11216-32.
    View in: PubMed
    Score: 0.416
  4. Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. Am J Physiol Heart Circ Physiol. 2013 Feb 01; 304(3):H415-26.
    View in: PubMed
    Score: 0.409
  5. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J Mol Cell Cardiol. 2011 Oct; 51(4):614-8.
    View in: PubMed
    Score: 0.360
  6. Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure. J Mol Cell Cardiol. 2007 Oct; 43(4):388-403.
    View in: PubMed
    Score: 0.282
  7. The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy. Aging (Albany NY). 2021 05 02; 13(9):12334-12358.
    View in: PubMed
    Score: 0.183
  8. Histone Deacetylase 3 (HDAC3)-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor Activity. J Biol Chem. 2015 Jun 19; 290(25):15559-15569.
    View in: PubMed
    Score: 0.121
  9. The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun. Nat Med. 2012 Nov; 18(11):1643-50.
    View in: PubMed
    Score: 0.102
  10. The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci Signal. 2011 Jul 19; 4(182):ra46.
    View in: PubMed
    Score: 0.093
  11. Mitochondrial SIRT3 and heart disease. Cardiovasc Res. 2010 Nov 01; 88(2):250-6.
    View in: PubMed
    Score: 0.087
  12. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest. 2009 Sep; 119(9):2758-71.
    View in: PubMed
    Score: 0.081
  13. Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2006 Oct; 291(4):H1545-53.
    View in: PubMed
    Score: 0.065
  14. Increased expression of poly(ADP-ribose) polymerase-1 contributes to caspase-independent myocyte cell death during heart failure. Am J Physiol Heart Circ Physiol. 2005 Feb; 288(2):H486-96.
    View in: PubMed
    Score: 0.058
  15. Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy. J Biol Chem. 2003 May 30; 278(22):20047-58.
    View in: PubMed
    Score: 0.052
  16. Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice. Am J Physiol Heart Circ Physiol. 2016 Apr 15; 310(8):H962-72.
    View in: PubMed
    Score: 0.032
  17. Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem. 2010 Jan 29; 285(5):3133-44.
    View in: PubMed
    Score: 0.021
  18. Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1388-97.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.