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Connection

Mahesh P. Gupta to Humans

This is a "connection" page, showing publications Mahesh P. Gupta has written about Humans.
Connection Strength

0.257
  1. Is nuclear sirtuin SIRT6 a master regulator of immune function? Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E399-E414.
    View in: PubMed
    Score: 0.024
  2. Cellular mechanisms promoting cachexia and how they are opposed by sirtuins 1. Can J Physiol Pharmacol. 2019 Apr; 97(4):235-245.
    View in: PubMed
    Score: 0.022
  3. The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy. Sci Rep. 2017 09 19; 7(1):11877.
    View in: PubMed
    Score: 0.019
  4. Role of Sirtuins in Regulating Pathophysiology of the Heart. Trends Endocrinol Metab. 2016 08; 27(8):563-573.
    View in: PubMed
    Score: 0.018
  5. Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. Circ Res. 2014 Jan 17; 114(2):368-78.
    View in: PubMed
    Score: 0.015
  6. SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Mol Cell Biol. 2014 Mar; 34(5):807-19.
    View in: PubMed
    Score: 0.015
  7. Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes. Mol Cell Biol. 2011 Jun; 31(11):2349-63.
    View in: PubMed
    Score: 0.012
  8. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J Mol Cell Cardiol. 2011 Oct; 51(4):614-8.
    View in: PubMed
    Score: 0.012
  9. Mitochondrial SIRT3 and heart disease. Cardiovasc Res. 2010 Nov 01; 88(2):250-6.
    View in: PubMed
    Score: 0.012
  10. Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process. Free Radic Biol Med. 2009 Mar 01; 46(5):680-91.
    View in: PubMed
    Score: 0.011
  11. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol. 2008 Oct; 28(20):6384-401.
    View in: PubMed
    Score: 0.010
  12. Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure. J Mol Cell Cardiol. 2007 Oct; 43(4):388-403.
    View in: PubMed
    Score: 0.010
  13. Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity. J Biol Chem. 2005 Dec 30; 280(52):43121-30.
    View in: PubMed
    Score: 0.008
  14. Increased expression of poly(ADP-ribose) polymerase-1 contributes to caspase-independent myocyte cell death during heart failure. Am J Physiol Heart Circ Physiol. 2005 Feb; 288(2):H486-96.
    View in: PubMed
    Score: 0.008
  15. Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure. J Biol Chem. 2003 Nov 07; 278(45):44935-48.
    View in: PubMed
    Score: 0.007
  16. Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability. Nucleic Acids Res. 2000 Aug 15; 28(16):3168-77.
    View in: PubMed
    Score: 0.006
  17. SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. Elife. 2018 03 05; 7.
    View in: PubMed
    Score: 0.005
  18. Molecular regulation of mitochondrial dynamics in cardiac disease. Biochim Biophys Acta Mol Cell Res. 2017 Jul; 1864(7):1260-1273.
    View in: PubMed
    Score: 0.005
  19. SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage. Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L68-L78.
    View in: PubMed
    Score: 0.005
  20. SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis. Oncotarget. 2016 Oct 25; 7(43):69321-69336.
    View in: PubMed
    Score: 0.005
  21. SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß. Mol Cell Biol. 2015 Dec 14; 36(5):678-92.
    View in: PubMed
    Score: 0.004
  22. Posttranslational modification of Sirt6 activity by peroxynitrite. Free Radic Biol Med. 2015 Feb; 79:176-85.
    View in: PubMed
    Score: 0.004
  23. SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer. Cancer Res. 2014 Oct 15; 74(20):5925-33.
    View in: PubMed
    Score: 0.004
  24. The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci Signal. 2011 Jul 19; 4(182):ra46.
    View in: PubMed
    Score: 0.003
  25. Nuclear import of serum response factor in airway smooth muscle. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):453-8.
    View in: PubMed
    Score: 0.003
  26. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest. 2009 Sep; 119(9):2758-71.
    View in: PubMed
    Score: 0.003
  27. SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Mol Cell Biol. 2009 Aug; 29(15):4116-29.
    View in: PubMed
    Score: 0.003
  28. Dephosphorylation and caspase processing generate distinct nuclear pools of histone deacetylase 4. Mol Cell Biol. 2007 Oct; 27(19):6718-32.
    View in: PubMed
    Score: 0.002
  29. Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts. Am J Physiol Heart Circ Physiol. 2002 Apr; 282(4):H1521-33.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.