Mahesh P. Gupta to Sirtuin 3
This is a "connection" page, showing publications Mahesh P. Gupta has written about Sirtuin 3.
Connection Strength
2.567
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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nat Commun. 2015 Apr 14; 6:6656.
Score: 0.519
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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Mol Cell Biol. 2014 Mar; 34(5):807-19.
Score: 0.473
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Mitochondrial SIRT3 and heart disease. Cardiovasc Res. 2010 Nov 01; 88(2):250-6.
Score: 0.375
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The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy. FASEB J. 2019 10; 33(10):10872-10888.
Score: 0.174
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Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice. Oncotarget. 2017 May 23; 8(21):34082-34098.
Score: 0.150
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SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage. Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L68-L78.
Score: 0.144
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SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis. Oncotarget. 2016 Oct 25; 7(43):69321-69336.
Score: 0.144
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Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice. Am J Physiol Heart Circ Physiol. 2016 Apr 15; 310(8):H962-72.
Score: 0.137
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SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß. Mol Cell Biol. 2015 Dec 14; 36(5):678-92.
Score: 0.136
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Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling. Cardiovasc Res. 2014 Sep 01; 103(4):485-97.
Score: 0.123
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Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem. 2010 Jan 29; 285(5):3133-44.
Score: 0.089
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SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol. 2008 Oct; 28(20):6384-401.
Score: 0.082
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Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest. 2009 Sep; 119(9):2758-71.
Score: 0.022