MirjamBoelensMirjam Boelens41.78927490000000-87.60125000000000230Boelens, Mirjamprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD002294Disorders19910750.588875Carcinoma, Squamous CellMedicine-General Internal MedicineAuthorship 125771829035379Raap M, Gronewold M, Christgen H, Glage S, Bentires-Alj M, Koren S, Derksen PW, Boelens M, Jonkers J, Lehmann U, Feuerhake F, Kuehnle E, Gluz O, Kates R, Nitz U, Harbeck N, Kreipe HH, Christgen MLaboratory investigation; a journal of technical methods and pathologyLobular carcinoma in situ and invasive lobular breast cancer are characterized by enhanced expression of transcription factor AP-2ß. Lab Invest. 2018 01; 98(1):117-129.Lab Invest2017-10-16T00:00:002017Lobular carcinoma in situ and invasive lobular breast cancer are characterized by enhanced expression of transcription factor AP-2ß.Authorship 245501D008175Disorders32822600.404557Lung NeoplasmsAuthorship 376941Authorship 327131Authorship 377281Authorship 424521Authorship 289701Authorship 45985415041794Bouïs D, Boelens MC, Peters E, Koolwijk P, Stob G, Kema IP, Klinkenberg M, Mulder NH, Hospers GAAngiogenesiscombination of vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) to improve angiogenic gene therapy. Angiogenesis. 2003; 6(3):185-92.Angiogenesis2003-01-01T00:00:002003combination of vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) to improve angiogenic gene therapy.Ben May Department of Cancer ResearchMedicine-Hematology and Oncology16489176Boelens MC, van den Berg A, Vogelzang I, Wesseling J, Postma DS, Timens W, Groen HJJournal of clinical pathologyDifferential expression and distribution of epithelial adhesion molecules in non-small cell lung cancer and normal bronchus. J Clin Pathol. 2007 Jun; 60(6):608-14.J Clin Pathol2006-02-17T00:00:002006Differential expression and distribution of epithelial adhesion molecules in non-small cell lung cancer and normal bronchus.19324446Boelens MC, Kok K, van der Vlies P, van der Vries G, Sietsma H, Timens W, Postma DS, Groen HJ, van den Berg ALung cancer (Amsterdam, Netherlands)Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis. Lung Cancer. 2009 Dec; 66(3):372-8.Lung Cancer2009-03-25T00:00:002009Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis.19334046Boelens MC, van den Berg A, Fehrmann RS, Geerlings M, de Jong WK, te Meerman GJ, Sietsma H, Timens W, Postma DS, Groen HJThe Journal of pathologyCurrent smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer. J Pathol. 2009 Jun; 218(2):182-91.J Pathol2009-06-01T00:00:002009Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer.Marina ChiaraGarassinoMarina Chiara Garassino41.7886000000000087.598699999999994025Garassino, Marina ChiaraProfessor20832896Boelens MC, Gustafson AM, Postma DS, Kok K, van der Vries G, van der Vlies P, Spira A, Lenburg ME, Geerlings M, Sietsma H, Timens W, van den Berg A, Groen HJLung cancer (Amsterdam, Netherlands)A chronic obstructive pulmonary disease related signature in squamous cell lung cancer. Lung Cancer. 2011 May; 72(2):177-83.Lung Cancer2010-09-15T00:00:002010A chronic obstructive pulmonary disease related signature in squamous cell lung cancer.17697374Boelens MC, te Meerman GJ, Gibcus JH, Blokzijl T, Boezen HM, Timens W, Postma DS, Groen HJ, van den Berg ABMC genomicsMicroarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances. BMC Genomics. 2007 Aug 15; 8:277.BMC Genomics2007-08-15T00:00:002007Microarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances.Authorship 1468525Authorship 1469213Authorship 1468512Authorship 1468506Authorship 146925933111480Koopman B, Groen HJM, Ligtenberg MJL, Grünberg K, Monkhorst K, de Langen AJ, Boelens MC, Paats MS, von der Thüsen JH, Dinjens WNM, Solleveld N, van Wezel T, Gelderblom H, Hendriks LE, Speel EM, Theunissen TE, Kroeze LI, Mehra N, Piet B, van der Wekken AJ, Ter Elst A, Timens W, Willems SM, Meijers RWJ, de Leng WWJ, van Lindert ASR, Radonic T, Hashemi SMS, Heideman DAM, Schuuring E, van Kempen LCThe oncologistMulticenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations. Oncologist. 2021 08; 26(8):e1347-e1358.Oncologist2020-11-10T00:00:002020Multicenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations.33204026Huijberts SCFA, Boelens MC, Bernards R, Opdam FLBritish journal of cancerMutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib. Br J Cancer. 2021 01; 124(1):176-182.Br J Cancer2020-11-18T00:00:002020Mutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib.33588111Radonic T, Geurts-Giele WRR, Samsom KG, Roemen GMJM, von der Thüsen JH, Thunnissen E, Meijssen IC, Sleddens HFBM, Dinjens WNM, Boelens MC, Weijers K, Speel EJM, Finn SP, O'Brien C, van Wezel T, Cohen D, Monkhorst K, Roepman P, Dubbink HJJournal of thoracic oncology : official publication of the International Association for the Study of Lung CancerRET Fluorescence In Situ Hybridization Analysis Is a Sensitive but Highly Unspecific Screening Method for RET Fusions in Lung Cancer. J Thorac Oncol. 2021 05; 16(5):798-806.J Thorac Oncol2021-02-12T00:00:002021RET Fluorescence In Situ Hybridization Analysis Is a Sensitive but Highly Unspecific Screening Method for RET Fusions in Lung Cancer.32135383Jebbink M, de Langen AJ, Boelens MC, Monkhorst K, Smit EFCancer treatment reviewsThe force of HER2 - A druggable target in NSCLC? Cancer Treat Rev. 2020 Jun; 86:101996.Cancer Treat Rev2020-02-28T00:00:002020The force of HER2 - A druggable target in NSCLC?33964451Roepman P, de Bruijn E, van Lieshout S, Schoenmaker L, Boelens MC, Dubbink HJ, Geurts-Giele WRR, Groenendijk FH, Huibers MMH, Kranendonk MEG, Roemer MGM, Samsom KG, Steehouwer M, de Leng WWJ, Hoischen A, Ylstra B, Monkhorst K, van der Hoeven JJM, Cuppen EThe Journal of molecular diagnostics : JMDClinical Validation of Whole Genome Sequencing for Cancer Diagnostics. J Mol Diagn. 2021 07; 23(7):816-833.J Mol Diagn2021-05-06T00:00:002021Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics.D018275Disorders41800.919711Carcinoma, Lobular21873975Yun J, Frankenberger CA, Kuo WL, Boelens MC, Eves EM, Cheng N, Liang H, Li WH, Ishwaran H, Minn AJ, Rosner MRThe EMBO journalSignalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J. 2011 Aug 26; 30(21):4500-14.EMBO J2011-08-26T00:00:002011Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer.Authorship 151398834849493Hondelink LM, Jebbink M, von der Thüsen JH, Cohen D, Dubbink HJ, Paats MS, Dingemans AC, de Langen AJ, Boelens MC, Smit EF, Postmus PE, van Wezel T, Monkhorst KJTO clinical and research reportsReal-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC. JTO Clin Res Rep. 2021 Dec; 2(12):100252.JTO Clin Res Rep2021-11-01T00:00:002021Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC.Authorship 1598521736635273Houthuijzen JM, de Bruijn R, van der Burg E, Drenth AP, Wientjens E, Filipovic T, Bullock E, Brambillasca CS, Pulver EM, Nieuwland M, de Rink I, van Diepen F, Klarenbeek S, Kerkhoven R, Brunton VG, Scheele CLGJ, Boelens MC, Jonkers JNature communicationsCD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer. Nat Commun. 2023 01 12; 14(1):183.Nat Commun2023-01-12T00:00:002023CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer.Authorship 161181236820955Wessels PH, Boelens MC, Monkhorst K, Sonke GS, van den Broek D, Brandsma DJournal of neuro-oncologyA review on genetic alterations in CNS metastases related to breast cancer treatment. Is there a role for liquid biopsies in CSF? J Neurooncol. 2023 Mar; 162(1):1-13.J Neurooncol2023-02-23T00:00:002023A review on genetic alterations in CNS metastases related to breast cancer treatment. Is there a role for liquid biopsies in CSF?D002869Disorders1113860.870762Chromosome Aberrationshttps://cgh.uchicago.edu/page/leadershipGlobal Healthhttps://www.uchicagomedicine.org/find-a-physician/physician/olufunmilayo-i-olopadeUChicago Medicinehttps://cancerbio.uchicago.edu/program/faculty/olufunmilayo-olopadeCancer Biologyhttps://www.uchicagomedicine.org/conditions-services/cancer/cancer-risk-preventionCancer Risk and Preventionhttps://neurology.uchicago.edu/faculty/jeremy-marks-md-phdDepartment of Neurologyhttps://www.uchicagomedicine.org/find-a-physician/physician/jeremy-d-marksUniversity of Chicago Hospitalshttps://rosnerlab.comRosner LabD015972Physiology31511960.666217Gene Expression Regulation, NeoplasticMedicineRadiologyUniversity of ChicagoEverett E.VokesEverett E. Vokes41.78927490000000-87.601250000000001920Vokes, Everett E.ProfessorRaviSalgiaRavi Salgia41.78927490000000-87.601250000000001937Salgia, RaviEmeritus/Emerita, ProfessorOlufunmilayoOlopade321vBIF1GuTQkntjbwjr93A=Olufunmilayo Olopade41.78927490000000-87.601250000000001960Olopade, OlufunmilayoProfessorCarol AnnStockingCarol Ann Stocking41.78927490000000-87.601250000000002124Stocking, Carol Ann0.8675240.0125998173research areas0.1044480.1044481coauthor of47.644.4627560similar to1121selected publicationsJenniferKimJennifer Kim41.78927490000000-87.601250000000002394Kim, JenniferMarshaRosnerMarsha Rosner41.78927490000000-87.60125000000000257Rosner, MarshaProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorLisa M.VinciLisa M. Vinci41.78927490000000-87.60125000000000628Vinci, Lisa M.ProfessorJeremyMarksJeremy Marks41.78927490000000-87.60125000000000708Marks, JeremyAssociate ProfessorJacobEcanowJacob Ecanow41.78927490000000-87.60125000000000828Ecanow, JacobClinical Assistant ProfessorAuthorship 1683501038006283Koster R, Schipper LJ, Giesbertz NAA, van Beek D, Mendeville M, Samsom KG, Rosenberg EH, Hogervorst FBL, Roepman P, Boelens MC, Bosch LJW, van den Berg JG, Meijer GA, Voest EE, Cuppen E, Ruijs MWG, van Wezel T, van der Kolk L, Monkhorst KGenetics in medicine : official journal of the American College of Medical GeneticsImpact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnostics. Genet Med. 2024 Feb; 26(2):101032.Genet Med2023-11-22T00:00:002023Impact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnostics.Authorship 168778638092944Samsom KG, Bosch LJW, Schipper LJ, Schout D, Roepman P, Boelens MC, Lalezari F, Klompenhouwer EG, de Langen AJ, Buffart TE, van Linder BMH, van Deventer K, van den Burg K, Unmehopa U, Rosenberg EH, Koster R, Hogervorst FBL, van den Berg JG, Riethorst I, Schoenmaker L, van Beek D, de Bruijn E, van der Hoeven JJM, van Snellenberg H, van der Kolk LE, Cuppen E, Voest EE, Meijer GA, Monkhorst KNature protocolsOptimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice. Nat Protoc. 2024 Mar; 19(3):700-726.Nat Protoc2023-12-13T00:00:002023Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice.true1true1true1true1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Clinical Assistant ProfessorClinical Assistant ProfessorAuthorship 67353125417103Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, Azzam DJ, Twyman-Saint Victor C, Wiemann BZ, Ishwaran H, Ter Brugge PJ, Jonkers J, Slingerland J, Minn AJCellExosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell. 2014 Oct 23; 159(3):499-513.Cell2014-10-23T00:00:002014Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways.Pediatrics-NeonatologyChicago60637ILAuthorship 911481127340177Annunziato S, Kas SM, Nethe M, Yücel H, Del Bravo J, Pritchard C, Bin Ali R, van Gerwen B, Siteur B, Drenth AP, Schut E, van de Ven M, Boelens MC, Klarenbeek S, Huijbers IJ, van Miltenburg MH, Jonkers JGenes & developmentModeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland. Genes Dev. 2016 06 15; 30(12):1470-80.Genes Dev2016-06-15T00:00:002016Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.Authorship 93365127524621Boelens MC, Nethe M, Klarenbeek S, de Ruiter JR, Schut E, Bonzanni N, Zeeman AL, Wientjens E, van der Burg E, Wessels L, van Amerongen R, Jonkers JCell reportsPTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma. Cell Rep. 2016 08 23; 16(8):2087-2101.Cell Rep2016-08-11T00:00:002016PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma.