Kenneth Polonsky to C-Peptide
This is a "connection" page, showing publications Kenneth Polonsky has written about C-Peptide.
Connection Strength
2.470
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Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism. J Vet Intern Med. 1996 May-Jun; 10(3):116-22.
Score: 0.125
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Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance. J Clin Endocrinol Metab. 1993 Jan; 76(1):44-8.
Score: 0.099
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Alterations in the kinetics of C-peptide and insulin secretion in hyperthyroidism. J Clin Endocrinol Metab. 1993 Jan; 76(1):79-84.
Score: 0.099
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Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes. Diabetes. 2012 Jul; 61(7):1793-800.
Score: 0.094
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Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes. 1992 Mar; 41(3):368-77.
Score: 0.094
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Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects. Metabolism. 1990 Aug; 39(8):827-32.
Score: 0.084
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TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes. 2010 Feb; 59(2):479-85.
Score: 0.080
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Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration. J Clin Endocrinol Metab. 1988 Nov; 67(5):1094-9.
Score: 0.074
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Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans. Diabetes. 1988 Oct; 37(10):1351-7.
Score: 0.074
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Reevaluation of urine C-peptide as measure of insulin secretion. Diabetes. 1988 Sep; 37(9):1195-201.
Score: 0.073
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Standardization of C-peptide measurements. Clin Chem. 2008 Jun; 54(6):1023-6.
Score: 0.072
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Quantitative study of insulin secretion and clearance in normal and obese subjects. J Clin Invest. 1988 Feb; 81(2):435-41.
Score: 0.070
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Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics. Diabetes. 1987 Oct; 36(10):1195-202.
Score: 0.069
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International comparison of C-peptide measurements. Clin Chem. 2007 Apr; 53(4):784-7.
Score: 0.066
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The limitations to and valid use of C-peptide as a marker of the secretion of insulin. Diabetes. 1986 Apr; 35(4):379-86.
Score: 0.062
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Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. J Clin Invest. 1986 Jan; 77(1):98-105.
Score: 0.061
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Current approaches to measurement of insulin secretion. Diabetes Metab Rev. 1986; 2(3-4):315-29.
Score: 0.061
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C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. J Clin Invest. 1984 Nov; 74(5):1821-9.
Score: 0.056
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C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations. Diabetes. 1984 May; 33(5):486-94.
Score: 0.054
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C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001. Diabetes. 2004 Jan; 53(1):250-64.
Score: 0.053
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Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction. J Clin Invest. 1983 Sep; 72(3):1114-23.
Score: 0.052
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Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance. Diabetologia. 2002 Apr; 45(4):509-17.
Score: 0.047
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Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E2-10.
Score: 0.043
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Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12. Diabetes. 1996 Nov; 45(11):1503-10.
Score: 0.032
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Insulin secretion in insulin-resistant women with a history of gestational diabetes. Metabolism. 1995 Aug; 44(8):1067-73.
Score: 0.030
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Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research. Diabetes. 1995 Jun; 44(6):705-17.
Score: 0.029
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Alterations in the patterns of insulin secretion before and after diagnosis of IDDM. Diabetes Care. 1995 Apr; 18(4):568-71.
Score: 0.029
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Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM. Diabetes. 1994 Jul; 43(7):871-7.
Score: 0.027
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Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes. Am J Physiol Gastrointest Liver Physiol. 2014 Feb 15; 306(4):G301-9.
Score: 0.026
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Prior feeding alters the response to the 50-g glucose challenge test in pregnancy. The Staub-Traugott effect revisited. Diabetes Care. 1993 Dec; 16(12):1551-6.
Score: 0.026
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Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus. J Clin Invest. 1993 Jul; 92(1):262-71.
Score: 0.026
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Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man. Metabolism. 1993 Jul; 42(7):829-33.
Score: 0.026
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Oscillatory insulin secretion after pancreas transplant. Diabetes. 1993 Jun; 42(6):855-61.
Score: 0.025
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Defects in beta-cell function in functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 1993 May; 76(5):1241-7.
Score: 0.025
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Analytical problems in detecting rapid insulin secretory pulses in normal humans. Am J Physiol. 1993 Feb; 264(2 Pt 1):E231-8.
Score: 0.025
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Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation. Diabetes. 1992 Oct; 41(10):1346-54.
Score: 0.024
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Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities. J Clin Endocrinol Metab. 1991 Apr; 72(4):934-44.
Score: 0.022
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Entrainment of pulsatile insulin secretion by oscillatory glucose infusion. J Clin Invest. 1991 Feb; 87(2):439-45.
Score: 0.022
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Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus. Am J Med. 1990 Aug 20; 89(2A):11S-16S; discussion 51S-53S.
Score: 0.021
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Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1989 Sep; 69(3):571-6.
Score: 0.020
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Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med. 1988 May 12; 318(19):1231-9.
Score: 0.018
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Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring). 2008 Jun; 16(6):1349-54.
Score: 0.018
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Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans. Am J Physiol. 1988 Mar; 254(3 Pt 1):E349-57.
Score: 0.018
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Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest. 1988 Feb; 81(2):442-8.
Score: 0.018
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Insulin Wakayama: familial mutant insulin syndrome in Japan. Diabetologia. 1987 Feb; 30(2):87-92.
Score: 0.016
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International trial of the Edmonton protocol for islet transplantation. N Engl J Med. 2006 Sep 28; 355(13):1318-30.
Score: 0.016
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Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide. J Clin Endocrinol Metab. 1986 Aug; 63(2):401-3.
Score: 0.016
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The measurement and validation of the nonsteady-state rates of C-peptide appearance in the dog. Diabetologia. 1986 Jul; 29(7):440-6.
Score: 0.016
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Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals. Diabetes. 2005 Nov; 54(11):3265-73.
Score: 0.015
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Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals. Diabetes. 2005 Aug; 54(8):2447-52.
Score: 0.015
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Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times. Diabetes. 2002 Feb; 51 Suppl 1:S227-33.
Score: 0.012
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GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E242-7.
Score: 0.011
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Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity. Diabetes. 2001 Jan; 50(1):150-8.
Score: 0.011
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Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. Diabetes. 2000 Aug; 49(8):1334-40.
Score: 0.010
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Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. Am J Physiol Endocrinol Metab. 2000 Mar; 278(3):E501-8.
Score: 0.010
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Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning. J Clin Endocrinol Metab. 1999 Sep; 84(9):3082-92.
Score: 0.010
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Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998 Feb 01; 128(3):176-85.
Score: 0.009
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Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs. Am J Physiol. 1998 02; 274(2):E346-56.
Score: 0.009
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Evidence that insulin can directly inhibit hepatic glucose production. Diabetologia. 1997 Nov; 40(11):1300-6.
Score: 0.009
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A novel point mutation in the insulin gene giving rise to hyperproinsulinemia. J Clin Endocrinol Metab. 1997 May; 82(5):1629-31.
Score: 0.008
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Late post-prandial hypoglycaemia as the sole presenting feature of secreting pancreatic beta-cell adenoma in a subtotally gastrectomized patient. Eur J Endocrinol. 1997 Jan; 136(1):96-9.
Score: 0.008
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Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging. Diabetologia. 1996 May; 39(5):564-72.
Score: 0.008
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Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation. Diabetes. 1996 Apr; 45(4):478-87.
Score: 0.008
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Abnormal temporal patterns of glucose tolerance in obesity: relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity. J Clin Endocrinol Metab. 1994 Dec; 79(6):1797-805.
Score: 0.007
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Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 1992 Jul; 35(7):681-9.
Score: 0.006
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Persistence of oscillatory insulin secretion in denervated islet cell autografts. Transplantation. 1991 Sep; 52(3):574-6.
Score: 0.006
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Hypoglycemia due to surreptitious injection of insulin. Identification of insulin species by high-performance liquid chromatography. Diabetes Care. 1991 Jul; 14(7):544-7.
Score: 0.006
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Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes. J Clin Endocrinol Metab. 1991 Feb; 72(2):444-54.
Score: 0.005
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Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1990 Jun; 70(6):1594-602.
Score: 0.005
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Pattern of postprandial carbohydrate metabolism and effects of portal and peripheral insulin delivery. Diabetes. 1990 Feb; 39(2):142-8.
Score: 0.005
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Effects of aging on insulin secretion. Diabetes. 1989 Dec; 38(12):1549-56.
Score: 0.005
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Oscillations in insulin secretion during constant glucose infusion in normal man: relationship to changes in plasma glucose. J Clin Endocrinol Metab. 1988 Aug; 67(2):307-14.
Score: 0.005
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Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism. 1986 Dec; 35(12):1137-46.
Score: 0.004
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Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. J Clin Invest. 1986 Nov; 78(5):1193-8.
Score: 0.004
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Natural history of intrahepatic canine islet cell autografts. J Clin Invest. 1986 Nov; 78(5):1339-48.
Score: 0.004
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In vivo pulsatility of pancreatic islet peptides. Am J Physiol. 1986 Aug; 251(2 Pt 1):E215-26.
Score: 0.004
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Long-term follow-up of canine segmental pancreatic autografts. Diabetes. 1985 Feb; 34(2):174-8.
Score: 0.004
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Pancreatic hormone profiles and metabolism posthepatectomy in the dog. Evidence for a hepatotrophic role of insulin, glucagon, and pancreatic polypeptide. Gastroenterology. 1984 Sep; 87(3):679-87.
Score: 0.003
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The effects of biosynthetic human proinsulin on carbohydrate metabolism. Diabetes. 1984 Aug; 33(8):762-70.
Score: 0.003
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Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome. N Engl J Med. 1984 May 17; 310(20):1288-94.
Score: 0.003
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Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. J Clin Invest. 1984 May; 73(5):1351-8.
Score: 0.003