Kenneth S. Polonsky to Female
This is a "connection" page, showing publications Kenneth S. Polonsky has written about Female.
Connection Strength
0.445
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Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes. Diabetes. 2012 Jul; 61(7):1793-800.
Score: 0.021
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Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. J Biol Chem. 2010 Jun 25; 285(26):19842-53.
Score: 0.018
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TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes. 2010 Feb; 59(2):479-85.
Score: 0.018
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Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance. Diabetes. 2009 Aug; 58(8):1869-78.
Score: 0.017
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Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. J Biol Chem. 2004 May 14; 279(20):20915-20.
Score: 0.012
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Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome. Am J Physiol Endocrinol Metab. 2004 Aug; 287(2):E241-6.
Score: 0.012
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Increased islet apoptosis in Pdx1+/- mice. J Clin Invest. 2003 Apr; 111(8):1147-60.
Score: 0.011
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Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance. Diabetologia. 2002 Apr; 45(4):509-17.
Score: 0.010
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Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse. Diabetes. 1999 May; 48(5):989-96.
Score: 0.009
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Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. J Clin Invest. 1997 Aug 01; 100(3):530-7.
Score: 0.008
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Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1997 Jul; 82(7):2108-16.
Score: 0.007
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Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1997 Feb; 82(2):524-30.
Score: 0.007
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Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12. Diabetes. 1996 Nov; 45(11):1503-10.
Score: 0.007
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Maturity onset diabetes of the young (MODY). Diabet Med. 1996 Sep; 13(9 Suppl 6):S90-5.
Score: 0.007
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Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function. Am J Physiol. 1996 Apr; 270(4 Pt 1):E572-9.
Score: 0.007
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Insulin secretion in insulin-resistant women with a history of gestational diabetes. Metabolism. 1995 Aug; 44(8):1067-73.
Score: 0.007
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Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Jul; 96(1):520-7.
Score: 0.007
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Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20. Diabetes. 1995 Jun; 44(6):699-704.
Score: 0.006
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Insulin secretion and clearance during low-dose graded glucose infusion. Am J Physiol. 1995 Jan; 268(1 Pt 1):E21-7.
Score: 0.006
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Compensation in pancreatic beta-cell function in subjects with glucokinase mutations. Diabetes. 1994 May; 43(5):718-23.
Score: 0.006
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Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes. Am J Physiol Gastrointest Liver Physiol. 2014 Feb 15; 306(4):G301-9.
Score: 0.006
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Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus. J Clin Invest. 1993 Jul; 92(1):262-71.
Score: 0.006
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Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man. Metabolism. 1993 Jul; 42(7):829-33.
Score: 0.006
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Defects in beta-cell function in functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 1993 May; 76(5):1241-7.
Score: 0.006
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Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance. J Clin Endocrinol Metab. 1993 Jan; 76(1):44-8.
Score: 0.005
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Alterations in the kinetics of C-peptide and insulin secretion in hyperthyroidism. J Clin Endocrinol Metab. 1993 Jan; 76(1):79-84.
Score: 0.005
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Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythm. Am J Physiol. 1992 Apr; 262(4 Pt 1):E467-75.
Score: 0.005
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Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes. 1992 Mar; 41(3):368-77.
Score: 0.005
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Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes. Obesity (Silver Spring). 2012 Jun; 20(6):1266-72.
Score: 0.005
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Postprandial triglyceride response in type 1 (insulin-dependent) diabetes mellitus is not altered by short-term deterioration in glycaemic control or level of postprandial insulin replacement. Diabetologia. 1991 Apr; 34(4):253-9.
Score: 0.005
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Ginseng and ginsenoside Re do not improve ß-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care. 2011 May; 34(5):1071-6.
Score: 0.005
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Postprandial lipoprotein metabolism in normal and obese subjects: comparison after the vitamin A fat-loading test. J Clin Endocrinol Metab. 1990 Oct; 71(4):1041-50.
Score: 0.005
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Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects. Metabolism. 1990 Aug; 39(8):827-32.
Score: 0.005
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Hypoglycemic thresholds for cognitive dysfunction in humans. Diabetes. 1990 Jul; 39(7):828-35.
Score: 0.005
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Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM. Diabetes Care. 1990 Jul; 13(7):748-55.
Score: 0.005
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Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. J Lipid Res. 2010 May; 51(5):907-13.
Score: 0.005
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Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome. Diabetes Res Clin Pract. 2009 Dec; 86(3):186-92.
Score: 0.004
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Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1989 Sep; 69(3):571-6.
Score: 0.004
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Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration. J Clin Endocrinol Metab. 1988 Nov; 67(5):1094-9.
Score: 0.004
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Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans. Diabetes. 1988 Oct; 37(10):1351-7.
Score: 0.004
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Reevaluation of urine C-peptide as measure of insulin secretion. Diabetes. 1988 Sep; 37(9):1195-201.
Score: 0.004
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Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med. 1988 May 12; 318(19):1231-9.
Score: 0.004
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Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring). 2008 Jun; 16(6):1349-54.
Score: 0.004
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Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans. Am J Physiol. 1988 Mar; 254(3 Pt 1):E349-57.
Score: 0.004
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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61.
Score: 0.004
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Insulin Wakayama: familial mutant insulin syndrome in Japan. Diabetologia. 1987 Feb; 30(2):87-92.
Score: 0.004
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The limitations to and valid use of C-peptide as a marker of the secretion of insulin. Diabetes. 1986 Apr; 35(4):379-86.
Score: 0.003
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Mutant insulin syndrome: identification of two families with [LeuA3]insulin and determination of its biological activity. Trans Assoc Am Physicians. 1986; 99:132-42.
Score: 0.003
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Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. J Clin Invest. 1986 Jan; 77(1):98-105.
Score: 0.003
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Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals. Diabetes. 2005 Aug; 54(8):2447-52.
Score: 0.003
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Insulin sensitivity by oral glucose minimal models: validation against clamp. Am J Physiol Endocrinol Metab. 2005 Dec; 289(6):E954-9.
Score: 0.003
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Glucose counterregulation in patients after pancreatectomy. Comparison with other clinical forms of diabetes. Diabetes. 1984 Nov; 33(11):1112-9.
Score: 0.003
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C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. J Clin Invest. 1984 Nov; 74(5):1821-9.
Score: 0.003
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Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation. Transplantation. 2004 Jul 15; 78(1):172-3.
Score: 0.003
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Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. J Clin Invest. 2003 Nov; 112(10):1550-60.
Score: 0.003
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Relation of counterregulatory responses to hypoglycemia in type I diabetics. N Engl J Med. 1982 Oct 28; 307(18):1106-12.
Score: 0.003
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Diagnosis of acromegaly in a patient with type 1 diabetes mellitus. Endocr Pract. 2002 Mar-Apr; 8(2):113-8.
Score: 0.003
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Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times. Diabetes. 2002 Feb; 51 Suppl 1:S227-33.
Score: 0.003
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Hepatic and renal metabolism of somatostatin-like immunoreactivity. Simultaneous assessment in the dog. J Clin Invest. 1981 Nov; 68(5):1149-57.
Score: 0.003
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Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. Nat Med. 2001 Oct; 7(10):1133-7.
Score: 0.003
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Insulin and glucagon breakthrough of somatostatin suppression: importance of portal vein hormone measurements. Diabetes. 1981 Aug; 30(8):664-9.
Score: 0.002
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Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes. Diabetes. 2001 Aug; 50(8):1828-33.
Score: 0.002
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Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. Diabetes. 2001 Feb; 50(2):322-8.
Score: 0.002
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Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E2-10.
Score: 0.002
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Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity. Diabetes. 2001 Jan; 50(1):150-8.
Score: 0.002
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Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. Diabetes. 2000 Aug; 49(8):1334-40.
Score: 0.002
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Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. Am J Physiol Endocrinol Metab. 2000 Mar; 278(3):E501-8.
Score: 0.002
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Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance. Diabetes. 1998 Aug; 47(8):1259-65.
Score: 0.002
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Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998 Feb 01; 128(3):176-85.
Score: 0.002
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Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs. Am J Physiol. 1998 02; 274(2):E346-56.
Score: 0.002
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Diminished insulin and glucagon secretory responses to arginine in nondiabetic subjects with a mutation in the hepatocyte nuclear factor-4alpha/MODY1 gene. Diabetes. 1997 Nov; 46(11):1749-54.
Score: 0.002
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Evidence that insulin can directly inhibit hepatic glucose production. Diabetologia. 1997 Nov; 40(11):1300-6.
Score: 0.002
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Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats. Biochem Biophys Res Commun. 1997 Aug 18; 237(2):476-80.
Score: 0.002
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Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. J Clin Endocrinol Metab. 1997 Jun; 82(6):1834-8.
Score: 0.002
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A novel point mutation in the insulin gene giving rise to hyperproinsulinemia. J Clin Endocrinol Metab. 1997 May; 82(5):1629-31.
Score: 0.002
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature. 1996 Dec 05; 384(6608):455-8.
Score: 0.002
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Ultradian oscillations of leptin secretion in humans. Biochem Biophys Res Commun. 1996 Nov 21; 228(3):733-8.
Score: 0.002
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Diurnal variations in cardiovascular function and glucose regulation in normotensive humans. Hypertension. 1996 Nov; 28(5):863-71.
Score: 0.002
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Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation. Diabetes. 1996 Apr; 45(4):478-87.
Score: 0.002
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Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function. N Engl J Med. 1995 Nov 23; 333(21):1386-90.
Score: 0.002
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Defects in insulin secretion and action in women with a history of gestational diabetes. Diabetes. 1995 May; 44(5):506-12.
Score: 0.002
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Measurement of proinsulin and intermediates. Validation of immunoassay methods by high-performance liquid chromatography. Diabetes. 1995 Apr; 44(4):437-40.
Score: 0.002
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A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion. J Clin Endocrinol Metab. 1994 Jul; 79(1):66-70.
Score: 0.002
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Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree. Diabetes. 1994 Jan; 43(1):40-6.
Score: 0.001
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Prior feeding alters the response to the 50-g glucose challenge test in pregnancy. The Staub-Traugott effect revisited. Diabetes Care. 1993 Dec; 16(12):1551-6.
Score: 0.001
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Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1993 Nov; 77(5):1287-93.
Score: 0.001
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Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1993 Jul; 77(1):6-10.
Score: 0.001
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Differential effects of glucose stimulation upon rapid pulses and ultradian oscillations of insulin secretion. J Clin Endocrinol Metab. 1993 Apr; 76(4):895-901.
Score: 0.001
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Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation. Diabetes. 1992 Oct; 41(10):1346-54.
Score: 0.001
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Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 1992 Jul; 35(7):681-9.
Score: 0.001
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A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto). J Clin Invest. 1992 Jun; 89(6):1902-7.
Score: 0.001
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Persistence of oscillatory insulin secretion in denervated islet cell autografts. Transplantation. 1991 Sep; 52(3):574-6.
Score: 0.001
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Hypoglycemia due to surreptitious injection of insulin. Identification of insulin species by high-performance liquid chromatography. Diabetes Care. 1991 Jul; 14(7):544-7.
Score: 0.001
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Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes. J Clin Endocrinol Metab. 1991 Feb; 72(2):444-54.
Score: 0.001
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Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1990 Jun; 70(6):1594-602.
Score: 0.001
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Pattern of postprandial carbohydrate metabolism and effects of portal and peripheral insulin delivery. Diabetes. 1990 Feb; 39(2):142-8.
Score: 0.001
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Effects of aging on insulin secretion. Diabetes. 1989 Dec; 38(12):1549-56.
Score: 0.001
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Oxygen uptake kinetics during exercise in diabetic neuropathy. J Appl Physiol (1985). 1988 Dec; 65(6):2665-71.
Score: 0.001
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Oscillations in insulin secretion during constant glucose infusion in normal man: relationship to changes in plasma glucose. J Clin Endocrinol Metab. 1988 Aug; 67(2):307-14.
Score: 0.001
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The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes. J Clin Endocrinol Metab. 1987 Mar; 64(3):476-81.
Score: 0.001
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Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. J Clin Invest. 1986 Nov; 78(5):1193-8.
Score: 0.001
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Natural history of intrahepatic canine islet cell autografts. J Clin Invest. 1986 Nov; 78(5):1339-48.
Score: 0.001
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In vivo pulsatility of pancreatic islet peptides. Am J Physiol. 1986 Aug; 251(2 Pt 1):E215-26.
Score: 0.001
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Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide. J Clin Endocrinol Metab. 1986 Aug; 63(2):401-3.
Score: 0.001
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Variable deterioration in cortical function during insulin-induced hypoglycemia. Diabetes. 1985 Jul; 34(7):677-85.
Score: 0.001
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Pancreatic hormone profiles and metabolism posthepatectomy in the dog. Evidence for a hepatotrophic role of insulin, glucagon, and pancreatic polypeptide. Gastroenterology. 1984 Sep; 87(3):679-87.
Score: 0.001
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The effects of biosynthetic human proinsulin on carbohydrate metabolism. Diabetes. 1984 Aug; 33(8):762-70.
Score: 0.001
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Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome. N Engl J Med. 1984 May 17; 310(20):1288-94.
Score: 0.001
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Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. J Clin Invest. 1984 May; 73(5):1351-8.
Score: 0.001
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Predominance of renal and absence of hepatic metabolism of pancreatic polypeptide in the dog. Am J Physiol. 1983 Aug; 245(2):E171-7.
Score: 0.001
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Lack of glucagon response to hypoglycemia in type I diabetics after long-term optimal therapy with a continuous subcutaneous insulin infusion pump. Diabetes. 1983 May; 32(5):398-402.
Score: 0.001
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Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. N Engl J Med. 1983 Jan 20; 308(3):119-25.
Score: 0.001
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A familial glucagonoma syndrome: genetic, clinical and biochemical features. Am J Med. 1981 May; 70(5):1017-26.
Score: 0.001
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Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon. Am J Physiol. 1981 Mar; 240(3):E233-44.
Score: 0.001
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Reduction in portal vein blood flow by somatostatin. Diabetes. 1979 Oct; 28(10):888-92.
Score: 0.001