Kenneth S. Polonsky to Mice
This is a "connection" page, showing publications Kenneth S. Polonsky has written about Mice.
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BH3-only molecule Bim mediates ß-cell death in IRS2 deficiency. Diabetes. 2014 Oct; 63(10):3378-87.
Score: 0.046
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Role of BH3-only molecules Bim and Puma in ß-cell death in Pdx1 deficiency. Diabetes. 2014 Aug; 63(8):2744-50.
Score: 0.046
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Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic ß cell death and diabetes. J Clin Invest. 2010 Nov; 120(11):4031-9.
Score: 0.036
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Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. J Biol Chem. 2010 Jun 25; 285(26):19842-53.
Score: 0.035
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Pdx1 and other factors that regulate pancreatic beta-cell survival. Diabetes Obes Metab. 2009 Nov; 11 Suppl 4:30-7.
Score: 0.034
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Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic ß-cells. Islets. 2009 Nov-Dec; 1(3):242-8.
Score: 0.034
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Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. J Biol Chem. 2009 Oct 02; 284(40):27664-73.
Score: 0.033
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Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19575-80.
Score: 0.028
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Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes. 2006 Oct; 55(10):2737-46.
Score: 0.027
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Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets. J Physiol. 2006 Apr 15; 572(Pt 2):379-92.
Score: 0.026
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Diabetic pancreatic beta cells ARNT all they should be. Cell Metab. 2005 Aug; 2(2):78-80.
Score: 0.025
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 04; 279(23):24794-802.
Score: 0.023
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Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. FASEB J. 2004 May; 18(7):878-80.
Score: 0.023
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Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. J Biol Chem. 2004 May 14; 279(20):20915-20.
Score: 0.023
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Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. Am J Physiol Endocrinol Metab. 2004 Jan; 286(1):E41-9.
Score: 0.022
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Organ alchemy: producing insulin in the liver. Nat Med. 2003 May; 9(5):504-5.
Score: 0.021
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A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism. 2003 May; 52(5):528-34.
Score: 0.021
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Increased islet apoptosis in Pdx1+/- mice. J Clin Invest. 2003 Apr; 111(8):1147-60.
Score: 0.021
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Calpains play a role in insulin secretion and action. Diabetes. 2001 Sep; 50(9):2013-20.
Score: 0.019
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The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes. Cell. 2001 Jun 15; 105(6):705-7.
Score: 0.019
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest. 2000 Aug; 106(3):329-33.
Score: 0.018
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. Am J Physiol Endocrinol Metab. 2000 Feb; 278(2):E340-51.
Score: 0.017
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Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse. Diabetes. 1999 May; 48(5):989-96.
Score: 0.016
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Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice. Diabetes. 1998 Dec; 47(12):1881-8.
Score: 0.016
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. J Biol Chem. 1998 Sep 18; 273(38):24457-64.
Score: 0.016
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest. 1998 Apr 15; 101(8):1623-32.
Score: 0.015
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Pancreatic ß-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak. J Biol Chem. 2016 Jun 24; 291(26):13529-34.
Score: 0.013
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Complex patterns of metabolic and Ca²? entrainment in pancreatic islets by oscillatory glucose. Biophys J. 2013 Jul 02; 105(1):29-39.
Score: 0.011
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Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10214-9.
Score: 0.009
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Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. J Lipid Res. 2010 May; 51(5):907-13.
Score: 0.009
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Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab. 2009 Apr; 9(4):350-61.
Score: 0.008
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Role of HNF-1alpha in regulating the expression of genes involved in cellular growth and proliferation in pancreatic beta-cells. Diabetes Res Clin Pract. 2009 Apr; 84(1):19-26.
Score: 0.008
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Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8452-7.
Score: 0.008
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Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. J Biol Chem. 2008 Jun 27; 283(26):18365-76.
Score: 0.008
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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61.
Score: 0.007
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Inhibition of calpain results in impaired contraction-stimulated GLUT4 translocation in skeletal muscle. Am J Physiol Endocrinol Metab. 2006 Sep; 291(3):E544-8.
Score: 0.007
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Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion. J Biol Chem. 2005 Feb 11; 280(6):4992-5003.
Score: 0.006
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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. J Clin Invest. 2004 Oct; 114(7):928-36.
Score: 0.006
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Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. Diabetes. 2004 Jan; 53(1):91-8.
Score: 0.006
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Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. J Clin Invest. 2003 Nov; 112(10):1550-60.
Score: 0.006
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Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem. 2003 Mar 14; 278(11):9796-801.
Score: 0.005
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Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes. 2002 Jun; 51(6):1851-8.
Score: 0.005
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Ginseng berry reduces blood glucose and body weight in db/db mice. Phytomedicine. 2002 Apr; 9(3):254-8.
Score: 0.005
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 2001 Nov; 50(11):2472-80.
Score: 0.005
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Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. Nat Med. 2001 Oct; 7(10):1133-7.
Score: 0.005
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Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. J Clin Invest. 1998 May 15; 101(10):2215-22.
Score: 0.004
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Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Proc Natl Acad Sci U S A. 1997 Jan 07; 94(1):219-26.
Score: 0.003
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature. 1996 Dec 05; 384(6608):455-8.
Score: 0.003