Yan YuanTsengYan Yuan Tseng41.78927490000000-87.601250000000002480Tseng, Yan Yuanprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonRamaRanganathanxWNnDKAbGPjRkHR2QFPt+2z5/syyp7BaZQ==Rama Ranganathan41.7886000000000087.598699999999993563Ranganathan, RamaProfessorBiochemistry and Molecular BiologyEcology and EvolutionRadiation and Cellular OncologyAuthorship 1166094Authorship 123937128211464Sanders MA, Zhang H, Mladenovic L, Tseng YY, Granneman JGScientific reportsMolecular Basis of ABHD5 Lipolysis Activation. Sci Rep. 2017 02 17; 7:42589.Sci Rep2017-02-17T00:00:002017Molecular Basis of ABHD5 Lipolysis Activation.16251508Tseng YY, Liang JMolecular biology and evolutionEstimation of amino acid residue substitution rates at local spatial regions and application in protein function inference: a Bayesian Monte Carlo approach. Mol Biol Evol. 2006 Feb; 23(2):421-36.Mol Biol Evol2005-10-26T00:00:002005Estimation of amino acid residue substitution rates at local spatial regions and application in protein function inference: a Bayesian Monte Carlo approach.D008958Concepts & Ideas24512840.706947Models, MolecularAuthorship 240093Authorship 130543530066644Yu K, Lung PY, Zhao T, Zhao P, Tseng YY, Zhang JBMC medical informatics and decision makingAutomatic extraction of protein-protein interactions using grammatical relationship graph. BMC Med Inform Decis Mak. 2018 07 23; 18(Suppl 2):42.BMC Med Inform Decis Mak2018-07-23T00:00:002018Automatic extraction of protein-protein interactions using grammatical relationship graph.Authorship 240811Authorship 132730431484772Lin JJ, Bhattacharjee MJ, Yu CP, Tseng YY, Li WHProceedings of the National Academy of Sciences of the United States of AmericaMany human RNA viruses show extraordinarily stringent selective constraints on protein evolution. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19009-19018.Proc Natl Acad Sci U S A2019-09-04T00:00:002019Many human RNA viruses show extraordinarily stringent selective constraints on protein evolution.Authorship 371251Authorship 302743Authorship 314761D011506Chemicals & Drugs3127770.656392ProteinsAuthorship 332991Authorship 377041Authorship 379891Authorship 392572Authorship 396321Authorship 473081Authorship 422652Authorship 486481Authorship 44308114681472Stitziel NO, Binkowski TA, Tseng YY, Kasif S, Liang JNucleic acids researchtopoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association. Nucleic Acids Res. 2004 Jan 01; 32(Database issue):D520-2.Nucleic Acids Res2004-01-01T00:00:002004topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association.14698285Tseng YY, Liang JJournal of molecular biologyAre residues in a protein folding nucleus evolutionarily conserved? J Mol Biol. 2004 Jan 23; 335(4):869-80.J Mol Biol2004-01-23T00:00:002004Are residues in a protein folding nucleus evolutionarily conserved?16922602Adamian L, Ouyang Z, Tseng YY, Liang JPhotochemistry and photobiologyEvolutionary patterns of retinal-binding pockets of type I rhodopsins and their functions. Photochem Photobiol. 2006 Nov-Dec; 82(6):1426-35.Photochem Photobiol2006-11-01T00:00:002006Evolutionary patterns of retinal-binding pockets of type I rhodopsins and their functions.19880384Tseng YY, Chen ZJ, Li WHNucleic acids researchfPOP: footprinting functional pockets of proteins by comparative spatial patterns. Nucleic Acids Res. 2010 Jan; 38(Database issue):D288-95.Nucleic Acids Res2009-10-30T00:00:002009fPOP: footprinting functional pockets of proteins by comparative spatial patterns.20731991Liang J, Tseng YY, Dundas J, Binkowski TA, Joachimiak A, Ouyang Z, Adamian LAdvances in protein chemistry and structural biologyChapter 4. Predicting and characterizing protein functions through matching geometric and evolutionary patterns of binding surfaces. Adv Protein Chem Struct Biol. 2008; 75:107-41.Adv Protein Chem Struct Biol2009-02-26T00:00:002009Chapter 4. Predicting and characterizing protein functions through matching geometric and evolutionary patterns of binding surfaces.19154742Tseng YY, Dundas J, Liang JJournal of molecular biologyPredicting protein function and binding profile via matching of local evolutionary and geometric surface patterns. J Mol Biol. 2009 Mar 27; 387(2):451-64.J Mol Biol2009-01-06T00:00:002009Predicting protein function and binding profile via matching of local evolutionary and geometric surface patterns.19406922Tseng YY, Dupree C, Chen ZJ, Li WHNucleic acids researchSplitPocket: identification of protein functional surfaces and characterization of their spatial patterns. Nucleic Acids Res. 2009 Jul; 37(Web Server issue):W384-9.Nucleic Acids Res2009-04-30T00:00:002009SplitPocket: identification of protein functional surfaces and characterization of their spatial patterns.21402946Tseng YY, Li WHProceedings of the National Academy of Sciences of the United States of AmericaEvolutionary approach to predicting the binding site residues of a protein from its primary sequence. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5313-8.Proc Natl Acad Sci U S A2011-03-14T00:00:002011Evolutionary approach to predicting the binding site residues of a protein from its primary sequence.19768800Adamian L, Gussin HA, Tseng YY, Muni NJ, Feng F, Qian H, Pepperberg DR, Liang JProtein science : a publication of the Protein SocietyStructural model of rho1 GABAC receptor based on evolutionary analysis: Testing of predicted protein-protein interactions involved in receptor assembly and function. Protein Sci. 2009 Nov; 18(11):2371-83.Protein Sci2009-11-01T00:00:002009Structural model of rho1 GABAC receptor based on evolutionary analysis: Testing of predicted protein-protein interactions involved in receptor assembly and function.19326458Tseng YY, Li WHProteinsIdentification of protein functional surfaces by the concept of a split pocket. Proteins. 2009 Sep; 76(4):959-76.Proteins2009-09-01T00:00:002009Identification of protein functional surfaces by the concept of a split pocket.Authorship 1479061133674876Bhattacharjee MJ, Lin JJ, Chang CY, Chiou YT, Li TN, Tai CW, Shiu TF, Chen CA, Chou CY, Chakraborty P, Tseng YY, Wang LH, Li WHMolecular biology and evolutionIdentifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2. Mol Biol Evol. 2021 06 25; 38(7):2715-2731.Mol Biol Evol2021-06-25T00:00:002021Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2.22238424Tseng YY, Li WHProceedings of the National Academy of Sciences of the United States of AmericaClassification of protein functional surfaces using structural characteristics. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1170-5.Proc Natl Acad Sci U S A2012-01-11T00:00:002012Classification of protein functional surfaces using structural characteristics.D051103Chemicals & Drugs340.9933811-Acylglycerol-3-Phosphate O-Acyltransferase22669905Tseng YY, Li WHNucleic acids researchPSC: protein surface classification. Nucleic Acids Res. 2012 Jul; 40(Web Server issue):W435-9.Nucleic Acids Res2012-06-04T00:00:002012PSC: protein surface classification.17294116Tseng YY, Liang JAnnals of biomedical engineeringPredicting enzyme functional surfaces and locating key residues automatically from structures. Ann Biomed Eng. 2007 Jun; 35(6):1037-42.Ann Biomed Eng2007-02-09T00:00:002007Predicting enzyme functional surfaces and locating key residues automatically from structures.Authorship 150753433186464Wu WS, Wang LJ, Yen HC, Tseng YYDatabase : the journal of biological databases and curationYQFC: a web tool to compare quantitative biological features between two yeast gene lists. Database (Oxford). 2020 01 01; 2020.Database (Oxford)2020-01-01T00:00:002020YQFC: a web tool to compare quantitative biological features between two yeast gene lists.17947099Tseng YY, Liang JConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual ConferenceAutomated method for predicting enzyme functional surfaces and locating key residues with accuracy and specificity. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:4552-5.Conf Proc IEEE Eng Med Biol Soc2006-01-01T00:00:002006Automated method for predicting enzyme functional surfaces and locating key residues with accuracy and specificity.Authorship 1534331Authorship 153411635173175Tseng YY, Sanders MA, Zhang H, Zhou L, Chou CY, Granneman JGScientific reportsStructural and functional insights into ABHD5, a ligand-regulated lipase co-activator. Sci Rep. 2022 02 16; 12(1):2565.Sci Rep2022-02-16T00:00:002022Structural and functional insights into ABHD5, a ligand-regulated lipase co-activator.35261984Lei X, Wang B, Perez-Rathke A, Tian W, Chou CY, Tseng YY, Liang J... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health InformaticsPredicting Oncogenic Missense Mutations. IEEE EMBS Int Conf Biomed Health Inform. 2019 May; 2019.IEEE EMBS Int Conf Biomed Health Inform2019-09-12T00:00:002019Predicting Oncogenic Missense Mutations.D030541Concepts & Ideas1312590.881908Databases, GeneticChuanHe1Gp8Cq8dHMzMknJtY0fp/Cv/+94=Chuan He0.000000000000000.000000000000003123He, ChuanProfessorhttp://www.thorntonlab.orgThornton Lab websitehttp://he-group.uchicago.eduMy Lab Sitehttp://sosnick.uchicago.edu/Sosnick lab websitehttp://kosslab.uchicago.eduKosslabhttp://recombinant-antibodies.orgRecombinant Antibody Networkhttp://ranganathanlab.org/Ranganathan LabD019295Occupations2395280.76301Computational BiologyAuthorship 163850537332013Wang B, Lei X, Tian W, Perez-Rathke A, Tseng YY, Liang JBriefings in bioinformaticsStructure-based pathogenicity relationship identifier for predicting effects of single missense variants and discovery of higher-order cancer susceptibility clusters of mutations. Brief Bioinform. 2023 07 20; 24(4).Brief Bioinform2023-07-20T00:00:002023Structure-based pathogenicity relationship identifier for predicting effects of single missense variants and discovery of higher-order cancer susceptibility clusters of mutations.ChemistryMedicinePediatricsUniversity of ChicagoAnthonyKossiakoff1mlmGLIcGOf5hHlsaUXv9Gq0+s+oAnthony Kossiakoff41.78927490000000-87.601250000000001188Kossiakoff, AnthonyProfessorLouisa TammyHoLouisa Tammy Ho41.78927490000000-87.601250000000001289Ho, Louisa TammyClinical Assistant ProfessorH. BarrettFrommeH. Barrett Fromme41.78927490000000-87.601250000000001674Fromme, H. BarrettProfessorJosephThorntonJoseph Thornton41.78927490000000-87.601250000000001722Thornton, JosephProfessorA.DrachlerA. Michael Drachler41.78927490000000-87.601250000000001787Drachler, A.SenthilkumarBakhara RajamohanSenthilkumar Bakhara Rajamohan41.78927490000000-87.601250000000002397Bakhara Rajamohan, SenthilkumarBulentAydoganBulent Aydogan41.78927490000000-87.601250000000002402Aydogan, BulentProfessor2.455920.0140682111research areas41.00253.7637960similar to1124selected publicationsTobin R.Sosnickw3B6BLIbEO/5hHlsaUXv9Gq0+s+oTobin R. Sosnick41.78927490000000-87.60125000000000744Sosnick, Tobin R.Professortrue1true1true1true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Clinical Assistant ProfessorClinical Assistant Professortrue1ProfessorProfessortrue1ProfessorProfessorChicago60637ILAuthorship 54750212662927Stitziel NO, Tseng YY, Pervouchine D, Goddeau D, Kasif S, Liang JJournal of molecular biologyStructural location of disease-associated single-nucleotide polymorphisms. J Mol Biol. 2003 Apr 11; 327(5):1021-30.J Mol Biol2003-04-11T00:00:002003Structural location of disease-associated single-nucleotide polymorphisms.