StephaniePalmerStephanie Palmer41.78927490000000-87.601250000000002489Palmer, StephanieI study how populations of neurons collectively encode information present in their inputs and how they perform computations on these signals. The brain performs several classes of computation including signal comparison, prediction, error correction, and learning. To investigate these phenomena, I work with experimentalists on a variety of systems: predictive coding in the retina and visual cortex of the rodent, motion coding in area MT, and temporal coding in the zebra finch song system. From these studies, several general principles have emerged, which guide my current research: the hypothesis that neurons are optimized to predict their future inputs, that information in neural populations is represented combinatorially, and that coding in sensori-motor systems is highly dynamic and behaviorally dependent. By working closely with experimentalists, we constrain and test these theories of neural population coding with detailed measurements.Associate Professorplugins:FeaturedVideosFeatured Videosprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:trainingAtOrganizationeducational organizationprns:trainingLocationtraining locationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:degreeEarneddegree earnedDepartmentvivo:educationalTrainingeducation and trainingEducational Trainingvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:orcidIdORCID idvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 100481327902829Nitzany EI, Loe ME, Palmer SE, Victor JDJournal of visionPerceptual interaction of local motion signals. J Vis. 2016 11 01; 16(14):22.J Vis2016-11-01T00:00:002016Perceptual interaction of local motion signals.Ecology and EvolutionOrganismal Biology and Anatomy29348208Sederberg AJ, MacLean JN, Palmer SEProceedings of the National Academy of Sciences of the United States of AmericaLearning to make external sensory stimulus predictions using internal correlations in populations of neurons. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):1105-1110.Proc Natl Acad Sci U S A2018-01-18T00:00:002018Learning to make external sensory stimulus predictions using internal correlations in populations of neurons.Authorship 1081123Neurobiology29116078Zhang W, Westerman E, Nitzany E, Palmer S, Kronforst MRNature communicationsTracing the origin and evolution of supergene mimicry in butterflies. Nat Commun. 2017 11 07; 8(1):1269.Nat Commun2017-11-07T00:00:002017Tracing the origin and evolution of supergene mimicry in butterflies.Authorship 1091174Authorship 11092313Authorship 113361430312315Lombardo JA, Macellaio MV, Liu B, Palmer SE, Osborne LCPLoS computational biologyState dependence of stimulus-induced variability tuning in macaque MT. PLoS Comput Biol. 2018 10; 14(10):e1006527.PLoS Comput Biol2018-10-12T00:00:002018State dependence of stimulus-induced variability tuning in macaque MT.30415702Westerman EL, VanKuren NW, Massardo D, Tenger-Trolander A, Zhang W, Hill RI, Perry M, Bayala E, Barr K, Chamberlain N, Douglas TE, Buerkle N, Palmer SE, Kronforst MRCurrent biology : CBAristaless Controls Butterfly Wing Color Variation Used in Mimicry and Mate Choice. Curr Biol. 2018 11 05; 28(21):3469-3474.e4.Curr Biol2018-10-25T00:00:002018Aristaless Controls Butterfly Wing Color Variation Used in Mimicry and Mate Choice.D004175Living Beings14440.950631Diptera05/1997Michigan State UniversityEast Lansing, MIMichigan State University, Chemical PhysicsBSChemical Physics04/2001University of OxfordEngland, UKUniversity of Oxford, Theoretical PhysicsDPhilTheoretical Physics09/2005University of California San FranciscoSan Francisco, CAUniversity of California San Francisco, NeurosciencePostdoctoralNeuroscience03/2012Princeton UniversityPrinceton, NJPrinceton University, NeurosciencePostdoctoralNeuroscienceAuthorship 135963232069273Johnston WJ, Palmer SE, Freedman DJPLoS computational biologyNonlinear mixed selectivity supports reliable neural computation. PLoS Comput Biol. 2020 02; 16(2):e1007544.PLoS Comput Biol2020-02-18T00:00:002020Nonlinear mixed selectivity supports reliable neural computation.Authorship 138305432546522Stern M, Arinze C, Perez L, Palmer SE, Murugan AProceedings of the National Academy of Sciences of the United States of AmericaSupervised learning through physical changes in a mechanical system. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):14843-14850.Proc Natl Acad Sci U S A2020-06-16T00:00:002020Supervised learning through physical changes in a mechanical system.BrentDoironBrent Doiron41.7886000000000087.598699999999993961Doiron, BrentProfessorJohn H.R.MaunsellJohn H.R. Maunsell0.000000000000000.000000000000002847Maunsell, John H.R.0000-0003-0018-4439ProfessorAuthorship 142549133296616Palmer SE, Wright BD, Doupe AJ, Kao MHJournal of neurophysiologyVariable but not random: temporal pattern coding in a songbird brain area necessary for song modification. J Neurophysiol. 2021 02 01; 125(2):540-555.J Neurophysiol2020-12-09T00:00:002020Variable but not random: temporal pattern coding in a songbird brain area necessary for song modification.Authorship 144860233684112Sachdeva V, Mora T, Walczak AM, Palmer SEPLoS computational biologyOptimal prediction with resource constraints using the information bottleneck. PLoS Comput Biol. 2021 03; 17(3):e1008743.PLoS Comput Biol2021-03-08T00:00:002021Optimal prediction with resource constraints using the information bottleneck.Authorship 146654434014926Wang S, Segev I, Borst A, Palmer SPLoS computational biologyMaximally efficient prediction in the early fly visual system may support evasive flight maneuvers. PLoS Comput Biol. 2021 05; 17(5):e1008965.PLoS Comput Biol2021-05-20T00:00:002021Maximally efficient prediction in the early fly visual system may support evasive flight maneuvers.Authorship 147038734096504Ding J, Chen A, Chung J, Acaron Ledesma H, Wu M, Berson DM, Palmer SE, Wei WeLifeSpatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuit. Elife. 2021 06 07; 10.Elife2021-06-07T00:00:002021Spatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuit.Authorship 154083235368649Kline AG, Palmer SENew journal of physicsGaussian Information Bottleneck and the Non-Perturbative Renormalization Group. New J Phys. 2022 Mar; 24(3).New J Phys2022-03-09T00:00:002022Gaussian Information Bottleneck and the Non-Perturbative Renormalization Group.D014795Anatomy291520.91215Visual PathwaysDarliMassardoDarli Massardo0.000000000000000.000000000000003079Massardo, DarliFellowhttp://bensmaialab.org/Bensmaia Lab Websitehttps://luolab.uchicago.edu/paleoct/UChicago PaleoCT http://www.freedmanlab.orgFreedman Laboratoryhttps://coateslab.uchicago.edu/Coates Lab Website http://palmerlab.uchicago.edu/Palmer Theory Grouphttp://neurobiology.uchicago.edu/page/wei-weiDepartmental Sitehttp://margoliashlab.uchicago.eduLab web sitehttps://voices.uchicago.edu/margoliashlab/Margoliash Labhttps://hatsopouloslab.uchicago.edu/Hatsopoulos Labhttps://voices.uchicago.edu/shermanlab/Sherman Lab Websitehttp://voices.uchicago.edu/weilab/Lab Websitehttps://maunselllab.orgMaunsell Laboratory Web Sitehttps://macleanlab.uchicago.eduMacLean Labhttps://www.kronforstlab.org/Kronforst Lab Websitehttps://luolab.uchicago.eduLuo Lab UChicagohttp://schmidtottlab.uchicago.edu/Schmidt-Ott Laboratory: Developmental Mechanisms and EvolutionD005426Physiology12220.97862Flight, AnimalD008959Concepts & Ideas1014050.769353Models, NeurologicalD012165Anatomy28660.940837Retinal Ganglion CellsAuthorship 163863637362058Wang S, Hoshal B, de Laittre EA, Marre O, Berry MJ, Palmer SEAdvances in neural information processing systemsLearning low-dimensional generalizable natural features from retina using a U-net. Adv Neural Inf Process Syst. 2022 Dec; 35:11355-11368.Adv Neural Inf Process Syst2022-12-01T00:00:002022Learning low-dimensional generalizable natural features from retina using a U-net.Ecology & EvolutionUniversity of ChicagoMarcus R.KronforstMarcus R. Kronforst41.78927490000000-87.601250000000001048Kronforst, Marcus R.ProfessorDavidFreedmanDavid Freedman41.78927490000000-87.601250000000001268Freedman, DavidProfessorMelina EHale2mpoB6Q1DO/RmHllZ0mg9mHvMelina E Hale41.78927490000000-87.601250000000001330Hale, Melina EProfessorZhe-XiLuoZhe-Xi Luo41.78927490000000-87.601250000000001439Luo, Zhe-XiProfessorDanielMargoliashDaniel Margoliash41.78927490000000-87.60125000000000155Margoliash, DanielProfessorJasonMacleanJason Maclean41.78927490000000-87.601250000000001551Maclean, JasonProfessorWeiWeiwGdgHIF1GuTQkntjbwjr93A=Wei Wei41.78927490000000-87.601250000000001677Wei, WeiProfessorMichael I.CoatesMichael I. Coates41.78927490000000-87.601250000000002032Coates, Michael I.ProfessorS. MurrayShermanxHFhDrMYGOL5hHlsaUXv9Gq0+s+oS. Murray Sherman41.78927490000000-87.601250000000002085Sherman, S. MurrayProfessorAuthorship 167156737609259Hoshal BD, Holmes CM, Bojanek K, Salisbury J, Berry MJ, Marre O, Palmer SEbioRxiv : the preprint server for biologyStimulus invariant aspects of the retinal code drive discriminability of natural scenes. bioRxiv. 2023 Aug 12.bioRxiv2023-08-12T00:00:002023Stimulus invariant aspects of the retinal code drive discriminability of natural scenes.0.8846880.0048651771research areas0.3321660.0429075coauthor of16.16981.6342960similar to1115selected publicationsUrs C.Schmidt-OttUrs C. Schmidt-Ott41.78927490000000-87.601250000000002507Schmidt-Ott, Urs C.0000-0002-1351-9472ProfessorSlimanBensmaiaSliman Bensmaia41.78927490000000-87.60125000000000297Bensmaia, SlimanProfessorNicholas G.HatsopoulosNicholas G. Hatsopoulos41.78927490000000-87.60125000000000709Hatsopoulos, Nicholas G.Professorhttp://weiw@uchicago.eduEmail: weiw@uchicago.edutrue1FellowFellowtrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 72529225695647Sederberg AJ, Palmer SE, MacLean JNJournal of neurophysiologyDecoding thalamic afferent input using microcircuit spiking activity. J Neurophysiol. 2015 Apr 01; 113(7):2921-33.J Neurophysiol2015-02-18T00:00:002015Decoding thalamic afferent input using microcircuit spiking activity.Chicago60637IL