GayatriRaghuramanGayatri Raghuraman41.78927490000000-87.601250000000002504Raghuraman, Gayatriplugins:FeaturedVideosFeatured Videosprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 101937228286252Zuniga MC, Raghuraman G, Hitchner E, Weyand C, Robinson W, Zhou WAtherosclerosisPKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages. Atherosclerosis. 2017 04; 259:51-59.Atherosclerosis2017-02-24T00:00:002017PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages.D000860DisordersPhenomena1726380.668873HypoxiaAnesthesia and Critical CareAuthorship 121087229361366Zuniga MC, Raghuraman G, Zhou WSurgeryPhysiologic levels of resistin induce a shift from proliferation to apoptosis in macrophage and VSMC co-culture. Surgery. 2018 04; 163(4):906-911.Surgery2018-02-01T00:00:002018Physiologic levels of resistin induce a shift from proliferation to apoptosis in macrophage and VSMC co-culture.Authorship 218132Authorship 211931Authorship 279372Authorship 361592Authorship 377301Authorship 308921Authorship 416303Authorship 302672Authorship 488373Authorship 465255Authorship 497191Authorship 428791Authorship 424731Authorship 451372Authorship 47209212213826Raghuraman G, Lapinski PE, Raghavan MThe Journal of biological chemistryTapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes. J Biol Chem. 2002 Nov 01; 277(44):41786-94.J Biol Chem2002-09-03T00:00:002002Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes.12501238Lapinski PE, Raghuraman G, Raghavan MThe Journal of biological chemistryNucleotide interactions with membrane-bound transporter associated with antigen processing proteins. J Biol Chem. 2003 Mar 07; 278(10):8229-37.J Biol Chem2002-12-25T00:00:002002Nucleotide interactions with membrane-bound transporter associated with antigen processing proteins.Pharmacological and Physiological Sciences16174096Procko E, Raghuraman G, Wiley DC, Raghavan M, Gaudet RImmunology and cell biologyIdentification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I. Immunol Cell Biol. 2005 Oct; 83(5):475-82.Immunol Cell Biol2005-10-01T00:00:002005Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I.16920953Thammavongsa V, Raghuraman G, Filzen TM, Collins KL, Raghavan MJournal of immunology (Baltimore, Md. : 1950)HLA-B44 polymorphisms at position 116 of the heavy chain influence TAP complex binding via an effect on peptide occupancy. J Immunol. 2006 Sep 01; 177(5):3150-61.J Immunol2006-09-01T00:00:002006HLA-B44 polymorphisms at position 116 of the heavy chain influence TAP complex binding via an effect on peptide occupancy.17114455Raghuraman G, Geng Y, Wang CRJournal of immunology (Baltimore, Md. : 1950)IFN-beta-mediated up-regulation of CD1d in bacteria-infected APCs. J Immunol. 2006 Dec 01; 177(11):7841-8.J Immunol2006-12-01T00:00:002006IFN-beta-mediated up-regulation of CD1d in bacteria-infected APCs.18818385Sharma SD, Raghuraman G, Lee MS, Prabhakar NR, Kumar GKJournal of applied physiology (Bethesda, Md. : 1985)Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing. J Appl Physiol (1985). 2009 Jan; 106(1):12-9.J Appl Physiol (1985)2008-09-25T00:00:002008Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing.19335094Raghuraman G, Rai V, Peng YJ, Prabhakar NR, Kumar GKAntioxidants & redox signalingPattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases. Antioxid Redox Signal. 2009 Aug; 11(8):1777-89.Antioxid Redox Signal2009-08-01T00:00:002009Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases.20556885Peng YJ, Nanduri J, Raghuraman G, Souvannakitti D, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NRProceedings of the National Academy of Sciences of the United States of AmericaH2S mediates O2 sensing in the carotid body. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10719-24.Proc Natl Acad Sci U S A2010-06-08T00:00:002010H2S mediates O2 sensing in the carotid body.20836657Raghuraman G, Kalari A, Dhingra R, Prabhakar NR, Kumar GKAntioxidants & redox signalingEnhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing. Antioxid Redox Signal. 2011 Apr 01; 14(7):1179-90.Antioxid Redox Signal2011-02-06T00:00:002011Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing.23080186Raghuraman G, Prabhakar NR, Kumar GKAdvances in experimental medicine and biologyDifferential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia. Adv Exp Med Biol. 2012; 758:381-5.Adv Exp Med Biol2012-01-01T00:00:002012Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia.21636565Peng YJ, Raghuraman G, Khan SA, Kumar GK, Prabhakar NRJournal of applied physiology (Bethesda, Md. : 1985)Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase. J Appl Physiol (1985). 2011 Oct; 111(4):964-70.J Appl Physiol (1985)2011-06-02T00:00:002011Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase.22016368Peng YJ, Nanduri J, Zhang X, Wang N, Raghuraman G, Seagard J, Kumar GK, Prabhakar NRJournal of applied physiology (Bethesda, Md. : 1985)Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia. J Appl Physiol (1985). 2012 Jan; 112(1):187-96.J Appl Physiol (1985)2011-10-20T00:00:002011Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia.22214405Rajamohan SB, Raghuraman G, Prabhakar NR, Kumar GKAntioxidants & redox signalingNADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):445-59.Antioxid Redox Signal2012-03-02T00:00:002012NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells.20969567Raghuraman G, Prabhakar NR, Kumar GKJournal of neurochemistryPost-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling. J Neurochem. 2010 Dec; 115(6):1568-78.J Neurochem2010-11-19T00:00:002010Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling.22744006Makarenko VV, Nanduri J, Raghuraman G, Fox AP, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NRAmerican journal of physiology. Cell physiologyEndogenous H2S is required for hypoxic sensing by carotid body glomus cells. Am J Physiol Cell Physiol. 2012 Nov 01; 303(9):C916-23.Am J Physiol Cell Physiol2012-06-27T00:00:002012Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.D017382Chemicals & Drugs1474800.796051Reactive Oxygen SpeciesD052243Chemicals & Drugs11140.991274ResistinD032389Anatomy491320.924724Myocytes, Smooth MuscleD019255Chemicals & Drugs40810.940312NADPH Oxidases24395806Peng YJ, Makarenko VV, Nanduri J, Vasavda C, Raghuraman G, Yuan G, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NRProceedings of the National Academy of Sciences of the United States of AmericaInherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1174-9.Proc Natl Acad Sci U S A2014-01-06T00:00:002014Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema.23913764Peng YJ, Nanduri J, Raghuraman G, Wang N, Kumar GK, Prabhakar NRExperimental physiologyRole of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia. Exp Physiol. 2013 Nov; 98(11):1620-30.Exp Physiol2013-08-02T00:00:002013Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia.https://integrativephysiology.uchicago.edu/Institute for Integrative Physiology and Center for Systems Biology of Oxygen SensingMedicinePediatricsUniversity of ChicagoGeorgeBakris0GBoa7McCszMknJtY0fp/Cv/+94=George Bakris41.78927490000000-87.601250000000001393Bakris, GeorgeProfessorNanduri R.Prabhakar2WNnD7QHEMzMknJtY0fp/Cv/+94=Nanduri R. Prabhakar41.78927490000000-87.601250000000001680Prabhakar, Nanduri R.ProfessorAaronFoxAaron Fox41.78927490000000-87.601250000000001772Fox, AaronProfessorYing-JiePengYing-Jie Peng41.78927490000000-87.601250000000002150Peng, Ying-JieResearch ProfessorRichardMitchellRichard W. Mitchell41.78927490000000-87.601250000000002456Mitchell, Richard1.253010.00979082204research areas1.237570.02767334coauthor of69.06062.8086960similar to1123selected publicationsJayasriNanduriJayasri Nanduri41.78927490000000-87.601250000000002544Nanduri, JayasriResearch ProfessorStephenArcherStephen Archer41.78927490000000-87.601250000000002615Archer, StephenProfessorShelleyZhangShelley Zhang41.78927490000000-87.60125000000000345Zhang, ShelleyRESEARCH ASSOCIATE (ASSISTANT PROFESSOR)JustinNauthJustin Nauth41.78927490000000-87.60125000000000596Nauth, JustinJianwuXuJianwu Xu41.78927490000000-87.60125000000000626Xu, JianwuJeffreyApfelbaumJeffrey Apfelbaum41.78927490000000-87.60125000000000685Apfelbaum, JeffreyProfessortrue1true1true1true1true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Research ProfessorResearch Professortrue1Research ProfessorResearch Professortrue1ProfessorProfessortrue1RESEARCH ASSOCIATE (ASSISTANT PROFESSOR)RESEARCH ASSOCIATE (ASSISTANT PROFESSOR)true1ProfessorProfessorAuthorship 711683Authorship 741415Authorship 77553525900831Yuan G, Vasavda C, Peng YJ, Makarenko VV, Raghuraman G, Nanduri J, Gadalla MM, Semenza GL, Kumar GK, Snyder SH, Prabhakar NRScience signalingProtein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal. 2015 Apr 21; 8(373):ra37.Sci Signal2015-04-21T00:00:002015Protein kinase G-regulated production of H2S governs oxygen sensing.Medicine-Emergency MedicineMedicine-EndocrinologyChicago60637ILAuthorship 93917327433899Zuniga MC, Tran TB, Baughman BD, Raghuraman G, Hitchner E, Rosen A, Zhou WAnnals of surgeryA Prospective Evaluation of Systemic Biomarkers and Cognitive Function Associated with Carotid Revascularization. Ann Surg. 2016 10; 264(4):659-65.Ann Surg2016-10-01T00:00:002016A Prospective Evaluation of Systemic Biomarkers and Cognitive Function Associated with Carotid Revascularization.Authorship 96010127573736Raghuraman G, Zuniga MC, Yuan H, Zhou WAtherosclerosisPKCe mediates resistin-induced NADPH oxidase activation and inflammation leading to smooth muscle cell dysfunction and intimal hyperplasia. Atherosclerosis. 2016 10; 253:29-37.Atherosclerosis2016-08-20T00:00:002016PKCe mediates resistin-induced NADPH oxidase activation and inflammation leading to smooth muscle cell dysfunction and intimal hyperplasia.Authorship 99572127681294Raghuraman G, Hsiung J, Zuniga MC, Baughman BD, Hitchner E, Guzman RJ, Zhou WJournal of cellular biochemistryEotaxin Augments Calcification in Vascular Smooth Muscle Cells. J Cell Biochem. 2017 03; 118(3):647-654.J Cell Biochem2016-11-28T00:00:002016Eotaxin Augments Calcification in Vascular Smooth Muscle Cells.