Eduardo Perozo to Potassium Channels
This is a "connection" page, showing publications Eduardo Perozo has written about Potassium Channels.
Connection Strength
8.757
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The gating cycle of a K+ channel at atomic resolution. Elife. 2017 11 22; 6.
Score: 0.529
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Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 2014 Apr 29; 53(16):2557-9.
Score: 0.412
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Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP. Biochemistry. 2014 Mar 18; 53(10):1627-36.
Score: 0.409
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Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1831-6.
Score: 0.405
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Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. J Am Chem Soc. 2012 Oct 03; 134(39):16360-9.
Score: 0.369
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Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11896-9.
Score: 0.340
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A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophys J. 2011 May 18; 100(10):2387-93.
Score: 0.337
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Structural mechanism of C-type inactivation in K(+) channels. Nature. 2010 Jul 08; 466(7303):203-8.
Score: 0.317
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Design and characterization of a constitutively open KcsA. FEBS Lett. 2010 Mar 19; 584(6):1133-8.
Score: 0.309
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A molecular mechanism for proton-dependent gating in KcsA. FEBS Lett. 2010 Mar 19; 584(6):1126-32.
Score: 0.308
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Voltage-dependent gating at the KcsA selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):319-22.
Score: 0.235
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Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces. Biochemistry. 2005 Jan 11; 44(1):62-71.
Score: 0.217
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The voltage sensor and the gate in ion channels. Adv Protein Chem. 2003; 63:211-41.
Score: 0.188
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New structural perspectives on K(+) channel gating. Structure. 2002 Aug; 10(8):1027-9.
Score: 0.183
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Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations. Biophys J. 2001 Nov; 81(5):2530-46.
Score: 0.174
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Structure of the KcsA channel intracellular gate in the open state. Nat Struct Biol. 2001 Oct; 8(10):883-7.
Score: 0.173
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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. J Gen Physiol. 2021 09 06; 153(9).
Score: 0.171
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Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J Gen Physiol. 2001 Feb; 117(2):165-80.
Score: 0.165
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Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis. J Gen Physiol. 2000 Jan; 115(1):29-32.
Score: 0.153
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Structural rearrangements underlying K+-channel activation gating. Science. 1999 Jul 02; 285(5424):73-8.
Score: 0.148
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Shedding light on voltage-dependent gating. J Gen Physiol. 1998 Oct; 112(4):373-6.
Score: 0.140
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Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel. J Gen Physiol. 2018 10 01; 150(10):1408-1420.
Score: 0.139
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Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nat Struct Biol. 1998 Jun; 5(6):459-69.
Score: 0.137
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pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 1998 Mar 10; 37(10):3229-36.
Score: 0.135
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy. FEBS Lett. 1998 Feb 20; 423(2):205-12.
Score: 0.135
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Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11145-11150.
Score: 0.131
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability. Biochemistry. 1997 Aug 19; 36(33):10343-52.
Score: 0.130
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Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy. J Am Chem Soc. 2017 07 05; 139(26):8837-8845.
Score: 0.127
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Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy. Science. 2016 09 02; 353(6303):1040-1044.
Score: 0.122
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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel. Biochim Biophys Acta. 2016 Jul; 1858(7 Pt B):1722-32.
Score: 0.117
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S4 mutations alter gating currents of Shaker K channels. Biophys J. 1994 Feb; 66(2 Pt 1):345-54.
Score: 0.102
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Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron. 1993 Aug; 11(2):353-8.
Score: 0.098
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Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature. 2013 Sep 05; 501(7465):121-4.
Score: 0.098
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Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):13008-13.
Score: 0.098
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Mechanism of Cd2+ coordination during slow inactivation in potassium channels. Structure. 2012 Aug 08; 20(8):1332-42.
Score: 0.091
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Gating currents in Shaker K+ channels. Implications for activation and inactivation models. Biophys J. 1992 Apr; 62(1):160-8; discussion 169-71.
Score: 0.089
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Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. J Gen Physiol. 2011 Dec; 138(6):571-80.
Score: 0.087
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Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis. J Bioenerg Biomembr. 1991 Aug; 23(4):599-613.
Score: 0.085
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions. J Gen Physiol. 1991 Jul; 98(1):1-17.
Score: 0.085
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions. J Gen Physiol. 1991 Jul; 98(1):19-34.
Score: 0.085
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On the structural basis of modal gating behavior in K(+) channels. Nat Struct Mol Biol. 2011 Jan; 18(1):67-74.
Score: 0.082
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Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions. Neuron. 1990 Nov; 5(5):685-90.
Score: 0.081
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Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 2010 Jul 08; 466(7303):272-5.
Score: 0.079
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Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation. J Gen Physiol. 1989 Jun; 93(6):1195-218.
Score: 0.073
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Crystal structure of full-length KcsA in its closed conformation. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6644-9.
Score: 0.073
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A quantitative description of KcsA gating I: macroscopic currents. J Gen Physiol. 2007 Nov; 130(5):465-78.
Score: 0.066
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A quantitative description of KcsA gating II: single-channel currents. J Gen Physiol. 2007 Nov; 130(5):479-96.
Score: 0.066
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Molecular driving forces determining potassium channel slow inactivation. Nat Struct Mol Biol. 2007 Nov; 14(11):1062-9.
Score: 0.066
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81.
Score: 0.061
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Molecular determinants of gating at the potassium-channel selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):311-8.
Score: 0.059
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Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3.
Score: 0.047
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Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11605-10.
Score: 0.046
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EPR approaches to ion channel structure and function. Novartis Found Symp. 2002; 245:146-58; discussion 158-64, 165-8.
Score: 0.044
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Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS). Pflugers Arch. 1994 Oct; 428(3-4):315-22.
Score: 0.027
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Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys J. 1994 Apr; 66(4):1011-21.
Score: 0.026
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Gating of Shaker K+ channels: I. Ionic and gating currents. Biophys J. 1994 Apr; 66(4):996-1010.
Score: 0.026
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Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system. Biochemistry. 1994 Feb 15; 33(6):1295-9.
Score: 0.025
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Molecular basis of gating charge immobilization in Shaker potassium channels. Science. 1991 Nov 01; 254(5032):679-83.
Score: 0.022
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Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data. Biophys J. 2008 Dec; 95(11):5349-61.
Score: 0.017