Ralph Weichselbaum to DNA Damage
This is a "connection" page, showing publications Ralph Weichselbaum has written about DNA Damage.
Connection Strength
2.767
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Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res. 2012 Jun 01; 18(11):3015-21.
Score: 0.310
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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18490-5.
Score: 0.243
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YTHDFs as radiotherapy checkpoints in tumor immunity. J Exp Med. 2025 Aug 04; 222(8).
Score: 0.192
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Relevance and irrelevance of DNA damage response to radiotherapy. DNA Repair (Amst). 2004 Aug-Sep; 3(8-9):1245-51.
Score: 0.181
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Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process. Int J Radiat Biol. 2000 Aug; 76(8):1037-43.
Score: 0.137
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DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy. Br J Cancer. 1996 Jul; 74(1):37-42.
Score: 0.103
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Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers. Oncotarget. 2016 Jun 07; 7(23):33919-33.
Score: 0.103
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From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy. Clin Cancer Res. 2016 Jan 01; 22(1):20-5.
Score: 0.098
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Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. Oncogene. 2015 May 21; 34(21):2807-13.
Score: 0.090
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DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site. Nucleic Acids Res. 2013 Jan; 41(2):764-74.
Score: 0.080
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p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 09; 44(5):785-96.
Score: 0.075
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Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities. Int J Radiat Biol. 1991 Jun; 59(6):1341-52.
Score: 0.073
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Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Mol Cancer Ther. 2011 Jul; 10(7):1185-93.
Score: 0.072
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Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer Res. 2007 Jul 15; 67(14):6889-98.
Score: 0.055
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Chemo-inducible gene therapy. Anticancer Drugs. 2005 Nov; 16(10):1053-8.
Score: 0.049
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c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem. 2005 Mar 25; 280(12):11147-51.
Score: 0.047
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Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol Cell Biol. 2000 Aug; 20(15):5370-80.
Score: 0.034
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Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage. Mol Cell Biol. 2000 Jul; 20(14):4979-89.
Score: 0.034
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Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem. 2000 Jan 07; 275(1):322-7.
Score: 0.033
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Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene. 1999 Oct 07; 18(41):5714-7.
Score: 0.032
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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature. 1999 Jun 24; 399(6738):814-7.
Score: 0.032
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Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2536-2548.
Score: 0.031
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Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol Cell Biol. 1999 Apr; 19(4):2986-97.
Score: 0.031
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Role for p300 in stabilization of p53 in the response to DNA damage. J Biol Chem. 1999 Jan 22; 274(4):1883-6.
Score: 0.031
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Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene. 1998 Dec 24; 17(25):3309-18.
Score: 0.031
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Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem. 1998 Feb 13; 273(7):3799-802.
Score: 0.029
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Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress. Biochim Biophys Acta. 1997 Oct 24; 1333(2):O1-7.
Score: 0.028
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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6939-42.
Score: 0.028
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Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature. 1997 Apr 17; 386(6626):732-5.
Score: 0.027
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Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer. Clin Cancer Res. 2017 Aug 01; 23(15):4493-4500.
Score: 0.027
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Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1437-40.
Score: 0.027
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Role for c-Abl tyrosine kinase in growth arrest response to DNA damage. Nature. 1996 Jul 18; 382(6588):272-4.
Score: 0.026
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The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1. Proc Natl Acad Sci U S A. 1996 Jul 09; 93(14):6898-901.
Score: 0.026
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Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 1995 Dec 15; 14(24):6148-56.
Score: 0.025
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Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature. 1995 Aug 31; 376(6543):785-8.
Score: 0.024
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide. Cancer Res. 1995 Mar 01; 55(5):991-4.
Score: 0.024
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Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer. Oral Oncol. 2014 Sep; 50(9):825-31.
Score: 0.022
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Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation. Biochemistry. 1993 Oct 12; 32(40):10607-13.
Score: 0.021
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Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells. Oncol Res. 1993; 5(3):139-44.
Score: 0.020
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Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation. Radiat Res. 1992 Mar; 129(3):345-50.
Score: 0.019
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Measurement of bioreduction rates of cells with distinct responses to ionizing radiation and cisplatin. Biochim Biophys Acta. 1991 Jul 10; 1093(2-3):121-4.
Score: 0.018
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Cellular and molecular aspects of human tumor radioresistance. Important Adv Oncol. 1991; 73-83.
Score: 0.018
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Radioresistant derivatives of an X-ray-sensitive CHO cell line exhibit distinct patterns of sensitivity to DNA-damaging agents. Carcinogenesis. 1990 Aug; 11(8):1265-9.
Score: 0.017
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Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution. Radiat Res. 1990 Jul; 123(1):1-6.
Score: 0.017
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
Score: 0.016
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Comparative analysis of the inherent radiosensitivity of ovarian carcinoma. Gynecol Obstet Invest. 1989; 28(4):215-8.
Score: 0.015
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Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells. Cancer Res. 1988 Aug 01; 48(15):4244-9.
Score: 0.015
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gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy. Curr Cancer Drug Targets. 2006 May; 6(3):197-205.
Score: 0.013
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Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review). Int J Oncol. 2004 Mar; 24(3):731-6.
Score: 0.011
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Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8411-8.
Score: 0.009
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The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem. 2000 Aug 04; 275(31):23899-903.
Score: 0.009
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Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol. 1998 Nov; 18(11):6719-28.
Score: 0.008
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Xrcc3 is required for assembly of Rad51 complexes in vivo. J Biol Chem. 1998 Aug 21; 273(34):21482-8.
Score: 0.007
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Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms. J Biol Chem. 1996 Sep 27; 271(39):23775-9.
Score: 0.007
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Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2. Cancer Res. 1996 Aug 15; 56(16):3617-21.
Score: 0.007
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Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth Differ. 1995 Apr; 6(4):363-70.
Score: 0.006
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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J Clin Invest. 1991 Aug; 88(2):691-5.
Score: 0.005