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Connection

Ralph Weichselbaum to Radiation Tolerance

This is a "connection" page, showing publications Ralph Weichselbaum has written about Radiation Tolerance.
Connection Strength

5.104
  1. Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res. 2012 Jun 01; 18(11):3015-21.
    View in: PubMed
    Score: 0.340
  2. IFN signaling at the nexus of the radiotherapy response in malignant peripheral nerve sheath tumors. J Clin Invest. 2026 Mar 02; 136(5).
    View in: PubMed
    Score: 0.221
  3. Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance. Clin Cancer Res. 2024 Oct 01; 30(19):4450-4463.
    View in: PubMed
    Score: 0.200
  4. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A. 2004 Feb 10; 101(6):1714-9.
    View in: PubMed
    Score: 0.191
  5. Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy. J Biol Chem. 2004 Jan 16; 279(3):2273-80.
    View in: PubMed
    Score: 0.187
  6. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591.
    View in: PubMed
    Score: 0.151
  7. Tumor-reprogrammed resident T cells resist radiation to control tumors. Nat Commun. 2019 09 02; 10(1):3959.
    View in: PubMed
    Score: 0.141
  8. The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines. Br J Cancer. 1999 Feb; 79(5-6):744-7.
    View in: PubMed
    Score: 0.135
  9. Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein. Cancer Res. 1998 Aug 01; 58(15):3215-20.
    View in: PubMed
    Score: 0.130
  10. ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response. Free Radic Biol Med. 2018 08 01; 123:39-52.
    View in: PubMed
    Score: 0.128
  11. Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nat Commun. 2017 11 23; 8(1):1736.
    View in: PubMed
    Score: 0.124
  12. TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response. Radiat Res. 2017 11; 188(5):579-590.
    View in: PubMed
    Score: 0.122
  13. Attenuation of G2-phase cell cycle checkpoint control is associated with increased frequencies of unrejoined chromosome breaks in human tumor cells. Radiat Res. 1996 Aug; 146(2):139-43.
    View in: PubMed
    Score: 0.114
  14. Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity. Free Radic Biol Med. 2016 10; 99:110-119.
    View in: PubMed
    Score: 0.113
  15. DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy. Br J Cancer. 1996 Jul; 74(1):37-42.
    View in: PubMed
    Score: 0.113
  16. Cellular and molecular mechanisms of radioresistance. Cancer Treat Res. 1995; 74:131-40.
    View in: PubMed
    Score: 0.102
  17. Radiation as an immune modulator. Semin Radiat Oncol. 2013 Oct; 23(4):273-80.
    View in: PubMed
    Score: 0.093
  18. Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure. PLoS One. 2013; 8(8):e69025.
    View in: PubMed
    Score: 0.092
  19. EPR oxygen images predict tumor control by a 50% tumor control radiation dose. Cancer Res. 2013 Sep 01; 73(17):5328-35.
    View in: PubMed
    Score: 0.092
  20. A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15; 73(14):4418-28.
    View in: PubMed
    Score: 0.091
  21. Molecular targets to overcome radioresistance. Semin Oncol. 1992 Aug; 19(4 Suppl 11):14-20.
    View in: PubMed
    Score: 0.086
  22. Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines. Radiat Res. 1992 May; 130(2):166-70.
    View in: PubMed
    Score: 0.085
  23. Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung. Int J Radiat Oncol Biol Phys. 1992; 24(1):183-4.
    View in: PubMed
    Score: 0.083
  24. Epigenetic effects on radiosensitivity: the extracellular matrix and growth factors. Eur J Cancer. 1992; 28A(4-5):723-4.
    View in: PubMed
    Score: 0.083
  25. Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities. Int J Radiat Biol. 1991 Jun; 59(6):1341-52.
    View in: PubMed
    Score: 0.079
  26. Cellular and molecular aspects of human tumor radioresistance. Important Adv Oncol. 1991; 73-83.
    View in: PubMed
    Score: 0.077
  27. Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy. Int J Radiat Oncol Biol Phys. 1990 Aug; 19(2):313-9.
    View in: PubMed
    Score: 0.075
  28. Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution. Radiat Res. 1990 Jul; 123(1):1-6.
    View in: PubMed
    Score: 0.075
  29. Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy. Cancer Res. 2010 Feb 15; 70(4):1534-43.
    View in: PubMed
    Score: 0.073
  30. STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med. 2009 Nov 05; 7:68.
    View in: PubMed
    Score: 0.071
  31. Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
    View in: PubMed
    Score: 0.069
  32. Faster repair of DNA double-strand breaks in radioresistant human tumor cells. Int J Radiat Oncol Biol Phys. 1988 Oct; 15(4):907-12.
    View in: PubMed
    Score: 0.066
  33. In vitro radiobiological parameters of human sarcoma cell lines. Int J Radiat Oncol Biol Phys. 1988 Oct; 15(4):937-42.
    View in: PubMed
    Score: 0.066
  34. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res. 2007 Oct 01; 67(19):9214-20.
    View in: PubMed
    Score: 0.062
  35. Radioresistant and repair proficient cells may determine radiocurability in human tumors. Int J Radiat Oncol Biol Phys. 1986 Apr; 12(4):637-9.
    View in: PubMed
    Score: 0.055
  36. How does antiangiogenic therapy affect brain tumor response to radiation? Nat Clin Pract Oncol. 2005 May; 2(5):232-3.
    View in: PubMed
    Score: 0.052
  37. Relevance and irrelevance of DNA damage response to radiotherapy. DNA Repair (Amst). 2004 Aug-Sep; 3(8-9):1245-51.
    View in: PubMed
    Score: 0.049
  38. Cellular X-ray repair parameters of early passage squamous cell carcinoma lines derived from patients with known responses to radiotherapy. Br J Cancer. 1984 May; 49(5):595-601.
    View in: PubMed
    Score: 0.049
  39. Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis. Int J Cancer. 2004 Mar 20; 109(2):214-9.
    View in: PubMed
    Score: 0.048
  40. In vitro radiosensitivity of fibroblasts derived from patients with retinoblastoma and abnormalities of chromosome 13. Retina. 1983; 3(2):126-30.
    View in: PubMed
    Score: 0.044
  41. Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage. Radiology. 1982 Nov; 145(2):511-3.
    View in: PubMed
    Score: 0.044
  42. Cellular repair factors influencing radiocurability of human malignant tumours. Br J Cancer. 1982 Jan; 45(1):10-6.
    View in: PubMed
    Score: 0.041
  43. Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J. 2002 Jan-Feb; 8(1):47-54.
    View in: PubMed
    Score: 0.041
  44. All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Sci Immunol. 2021 06 15; 6(60).
    View in: PubMed
    Score: 0.040
  45. The AIM2 and NLRP3 inflammasomes trigger IL-1-mediated antitumor effects during radiation. Sci Immunol. 2021 05 07; 6(59).
    View in: PubMed
    Score: 0.040
  46. In vitro radiosensitivity of human leukemia cell lines. Radiology. 1981 May; 139(2):485-7.
    View in: PubMed
    Score: 0.039
  47. Methodological Development of Combination Drug and Radiotherapy in Basic and Clinical Research. Clin Cancer Res. 2020 09 15; 26(18):4723-4736.
    View in: PubMed
    Score: 0.037
  48. X-ray sensitivity of human tumor cells in vitro. Int J Radiat Oncol Biol Phys. 1980 Apr; 6(4):437-40.
    View in: PubMed
    Score: 0.037
  49. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 1999 Jul 15; 59(14):3374-8.
    View in: PubMed
    Score: 0.035
  50. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res. 1999 May 01; 59(9):2055-8.
    View in: PubMed
    Score: 0.034
  51. Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018 09 18; 49(3):490-503.e4.
    View in: PubMed
    Score: 0.033
  52. Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts. Cancer Res. 1997 Oct 01; 57(19):4205-9.
    View in: PubMed
    Score: 0.031
  53. Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1437-40.
    View in: PubMed
    Score: 0.030
  54. In vitro radiosensitivity of human dipliod fibroblasts derived from patients with unusual clinical responses to radiation. Radiology. 1976 Nov; 121(2):479-82.
    View in: PubMed
    Score: 0.029
  55. Genetic radiotherapy overcomes tumor resistance to cytotoxic agents. Cancer Res. 1995 Dec 01; 55(23):5561-5.
    View in: PubMed
    Score: 0.027
  56. Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):555-62.
    View in: PubMed
    Score: 0.027
  57. From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy. Clin Cancer Res. 2016 Jan 01; 22(1):20-5.
    View in: PubMed
    Score: 0.027
  58. Chromosome changes characterizing in vitro response to radiation in human squamous cell carcinoma lines. Cancer Res. 1993 Nov 15; 53(22):5542-7.
    View in: PubMed
    Score: 0.024
  59. p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res. 1993 Aug 15; 53(16):3667-9.
    View in: PubMed
    Score: 0.023
  60. Radioresistant derivatives of radiosensitive CHO cells obtained following treatment with 5-azacytidine retain their sensitivity to cisplatin. Radiat Res. 1991 Aug; 127(2):226-9.
    View in: PubMed
    Score: 0.020
  61. Possible applications of biotechnology to radiotherapy. Eur J Cancer. 1991; 27(4):405-7.
    View in: PubMed
    Score: 0.019
  62. Radioresistant derivatives of an X-ray-sensitive CHO cell line exhibit distinct patterns of sensitivity to DNA-damaging agents. Carcinogenesis. 1990 Aug; 11(8):1265-9.
    View in: PubMed
    Score: 0.019
  63. Radiobiological characterization of 53 human tumor cell lines. Int J Radiat Biol. 1989 Nov; 56(5):553-60.
    View in: PubMed
    Score: 0.018
  64. Radioresistant tumor cell lines derived from head and neck radiation failures. Head Neck. 1989 Jul-Aug; 11(4):343-8.
    View in: PubMed
    Score: 0.017
  65. Comparative analysis of the inherent radiosensitivity of ovarian carcinoma. Gynecol Obstet Invest. 1989; 28(4):215-8.
    View in: PubMed
    Score: 0.017
  66. Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy. Int J Radiat Oncol Biol Phys. 1988 Sep; 15(3):575-9.
    View in: PubMed
    Score: 0.016
  67. Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes. J Surg Oncol. 1988 Aug; 38(4):257-60.
    View in: PubMed
    Score: 0.016
  68. The raf oncogene is associated with a radiation-resistant human laryngeal cancer. Science. 1987 Aug 28; 237(4818):1039-41.
    View in: PubMed
    Score: 0.015
  69. The maximum recovery potential of human tumor cells may predict clinical outcome in radiotherapy. Int J Radiat Oncol Biol Phys. 1987 May; 13(5):709-13.
    View in: PubMed
    Score: 0.015
  70. Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients. Proc Natl Acad Sci U S A. 1986 Apr; 83(8):2684-8.
    View in: PubMed
    Score: 0.014
  71. The role of DNA repair processes in the response of human tumors to fractionated radiotherapy. Int J Radiat Oncol Biol Phys. 1984 Jul; 10(7):1127-34.
    View in: PubMed
    Score: 0.012
  72. Potentially lethal damage repair as a possible determinant of human tumour radiosensitivity. Radiother Oncol. 1984 Jan; 1(3):263-9.
    View in: PubMed
    Score: 0.012
  73. Chemical modulation of the hypoxic fraction in the treatment of head and neck cancer. Ann Otol Rhinol Laryngol. 1982 Jul-Aug; 91(4 Pt 1):461-4.
    View in: PubMed
    Score: 0.011
  74. Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains. Mutat Res. 1981 Nov; 84(1):157-67.
    View in: PubMed
    Score: 0.010
  75. Phosphorous metabolite and cell cycle kinetic response of two human squamous cell carcinomas to radiation. Cancer Res. 1992 Oct 01; 52(19):5299-306.
    View in: PubMed
    Score: 0.005
  76. Heterogeneous response to X-ray and ultraviolet light irradiations of cultured skin fibroblasts in two families with Gardner's Syndrome. J Natl Cancer Inst. 1982 May; 68(5):697-701.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.