Derek Wainwright to Animals
This is a "connection" page, showing publications Derek Wainwright has written about Animals.
Connection Strength
0.991
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Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence. Clin Cancer Res. 2023 12 01; 29(23):4973-4989.
Score: 0.058
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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma. J Med Chem. 2022 12 08; 65(23):15642-15662.
Score: 0.054
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Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies. Front Immunol. 2020; 11:1185.
Score: 0.046
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Quantification of IDO1 enzyme activity in normal and malignant tissues. Methods Enzymol. 2019; 629:235-256.
Score: 0.043
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IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma. Clin Cancer Res. 2018 06 01; 24(11):2559-2573.
Score: 0.039
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IDO1 in cancer: a Gemini of immune checkpoints. Cell Mol Immunol. 2018 May; 15(5):447-457.
Score: 0.039
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The Boosting Potential of Bacteria in Cancer Immunotherapy. Trends Mol Med. 2017 07; 23(7):580-582.
Score: 0.037
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Therapeutic Hypothesis Testing With Rodent Brain Tumor Models. Neurotherapeutics. 2017 04; 14(2):385-392.
Score: 0.037
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Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma. Brain Behav Immun. 2017 May; 62:24-29.
Score: 0.036
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Advanced age negatively impacts survival in an experimental brain tumor model. Neurosci Lett. 2016 Sep 06; 630:203-208.
Score: 0.035
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Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy. Clin Cancer Res. 2015 Dec 15; 21(24):5427-33.
Score: 0.033
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The role of IDO in brain tumor immunotherapy. J Neurooncol. 2015 Jul; 123(3):395-403.
Score: 0.031
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Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res. 2014 Oct 15; 20(20):5290-301.
Score: 0.030
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IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res. 2012 Nov 15; 18(22):6110-21.
Score: 0.027
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Recent developments on immunotherapy for brain cancer. Expert Opin Emerg Drugs. 2012 Jun; 17(2):181-202.
Score: 0.026
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Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors. Neuro Oncol. 2011 Dec; 13(12):1308-23.
Score: 0.025
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The expression of BST2 in human and experimental mouse brain tumors. Exp Mol Pathol. 2011 Aug; 91(1):440-6.
Score: 0.024
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The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma. PLoS One. 2010 Oct 23; 5(10):e15390.
Score: 0.023
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Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy. Neurosci Lett. 2010 Feb 26; 471(1):10-4.
Score: 0.022
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Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. J Neuroimmunol. 2009 Nov 30; 216(1-2):66-75.
Score: 0.022
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NKG2C/KLRC2 tumor cell expression enhances immunotherapeutic efficacy against glioblastoma. J Immunother Cancer. 2024 Aug 30; 12(8).
Score: 0.015
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Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation. Aging Cell. 2024 Aug; 23(8):e14190.
Score: 0.015
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Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression. Nat Commun. 2024 Mar 05; 15(1):1987.
Score: 0.015
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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry. J Immunother Cancer. 2022 07; 10(7).
Score: 0.013
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Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma. Cancer Immunol Res. 2022 06 03; 10(6):770-784.
Score: 0.013
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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957.
Score: 0.013
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Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma. Clin Cancer Res. 2021 12 01; 27(23):6514-6528.
Score: 0.012
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NK cell-based cancer immunotherapy: from basic biology to clinical development. J Hematol Oncol. 2021 01 06; 14(1):7.
Score: 0.012
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Targeting CD73 to augment cancer immunotherapy. Curr Opin Pharmacol. 2020 08; 53:66-76.
Score: 0.012
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Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma. Clin Cancer Res. 2020 10 01; 26(19):5232-5245.
Score: 0.011
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Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. J Hematol Oncol. 2020 06 09; 13(1):74.
Score: 0.011
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Receptor tyrosine kinase signaling regulates different modes of Groucho-dependent control of Dorsal. Curr Biol. 2000 Jan 13; 10(1):51-4.
Score: 0.011
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CD73: an emerging checkpoint for cancer immunotherapy. Immunotherapy. 2019 08; 11(11):983-997.
Score: 0.011
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A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model. Neurotherapeutics. 2018 10; 15(4):1127-1138.
Score: 0.010
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Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: a report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer. J Immunother Cancer. 2017 09 19; 5(1):77.
Score: 0.009
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Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival. Clin Cancer Res. 2017 Nov 01; 23(21):6650-6660.
Score: 0.009
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Developmental therapeutics for patients with breast cancer and central nervous system metastasis: current landscape and future perspectives. Ann Oncol. 2017 01 01; 28(1):44-56.
Score: 0.009
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CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells. Cancer Res. 2016 10 01; 76(19):5671-5682.
Score: 0.009
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Updates from the Neuro-Oncology Section of the 2015 American Neurological Association Annual Meeting. Future Oncol. 2016 Jan; 12(2):143-7.
Score: 0.008
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Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma. J Immunol. 2015 Jul 01; 195(1):367-76.
Score: 0.008
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Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29; 10(24):5137-50.
Score: 0.008
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Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma. Cancer Gene Ther. 2014 Jan; 21(1):38-44.
Score: 0.007
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Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model. J Neuroimmunol. 2014 Jan 15; 266(1-2):33-42.
Score: 0.007
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Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma. Biomaterials. 2014 Jan; 35(4):1249-56.
Score: 0.007
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Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy. Small. 2013 Dec 20; 9(24):4123-9.
Score: 0.007
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Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor a2. J Biol Chem. 2012 Aug 31; 287(36):30215-27.
Score: 0.007
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CD4+ T cell-mediated neuroprotection is independent of T cell-derived BDNF in a mouse facial nerve axotomy model. Brain Behav Immun. 2012 Aug; 26(6):886-90.
Score: 0.006
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The challenge for gene therapy: innate immune response to adenoviruses. Oncotarget. 2011 Mar; 2(3):113-21.
Score: 0.006
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Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model. Neoplasia. 2010 Oct; 12(10):837-47.
Score: 0.006
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IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection. Brain Behav Immun. 2011 Jul; 25(5):820-9.
Score: 0.006
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Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model. Mol Ther. 2010 Oct; 18(10):1846-56.
Score: 0.006
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Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy. Brain Behav Immun. 2008 May; 22(4):528-37.
Score: 0.005