Hae Kyung Im to Humans
This is a "connection" page, showing publications Hae Kyung Im has written about Humans.
Connection Strength
0.647
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scPrediXcan integrates deep learning methods and single-cell data into a cell-type-specific transcriptome-wide association study framework. Cell Genom. 2025 May 14; 5(5):100875.
Score: 0.030
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Meet the author: Hae Kyung Im. Cell Genom. 2025 May 14; 5(5):100880.
Score: 0.030
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RatXcan: A framework for cross-species integration of genome-wide association and gene expression data. PLoS Genet. 2025 Mar; 21(3):e1011583.
Score: 0.029
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BrainXcan identifies brain features associated with behavioral and psychiatric traits using large-scale genetic and imaging data. Dev Cogn Neurosci. 2025 Jun; 73:101542.
Score: 0.029
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A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer. Am J Hum Genet. 2024 06 06; 111(6):1100-1113.
Score: 0.028
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Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries. Genome Biol. 2022 01 13; 23(1):23.
Score: 0.024
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ukbREST: efficient and streamlined data access for reproducible research in large biobanks. Bioinformatics. 2019 06 01; 35(11):1971-1973.
Score: 0.020
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Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. Lancet Respir Med. 2019 06; 7(6):509-522.
Score: 0.019
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Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits. Genet Epidemiol. 2019 09; 43(6):596-608.
Score: 0.019
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Integrating predicted transcriptome from multiple tissues improves association detection. PLoS Genet. 2019 01; 15(1):e1007889.
Score: 0.019
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Nat Commun. 2018 05 08; 9(1):1825.
Score: 0.018
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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues. PLoS Genet. 2016 Nov; 12(11):e1006423.
Score: 0.016
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A gene-based association method for mapping traits using reference transcriptome data. Nat Genet. 2015 Sep; 47(9):1091-8.
Score: 0.015
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Poly-omic prediction of complex traits: OmicKriging. Genet Epidemiol. 2014 Jul; 38(5):402-15.
Score: 0.014
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Quantitative allelic test--a fast test for very large association studies. Genet Epidemiol. 2013 Dec; 37(8):831-9.
Score: 0.013
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On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy. Am J Hum Genet. 2012 Apr 06; 90(4):591-8.
Score: 0.012
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Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer. PLoS Genet. 2012 Feb; 8(2):e1002525.
Score: 0.012
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The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Nat Genet. 2025 Apr; 57(4):786-796.
Score: 0.007
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Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits. Genome Biol. 2025 Feb 03; 26(1):19.
Score: 0.007
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Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits. Am J Hum Genet. 2024 03 07; 111(3):445-455.
Score: 0.007
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Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility. Cancer Epidemiol Biomarkers Prev. 2023 09 01; 32(9):1198-1207.
Score: 0.007
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Revealing polygenic pleiotropy using genetic risk scores for asthma. HGG Adv. 2023 10 12; 4(4):100233.
Score: 0.007
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Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations. HGG Adv. 2023 10 12; 4(4):100216.
Score: 0.007
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Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation. Mol Syst Biol. 2023 08 08; 19(8):e11407.
Score: 0.006
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The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci. Nat Comput Sci. 2023 05; 3(5):403-417.
Score: 0.006
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A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes. Am J Hum Genet. 2023 06 01; 110(6):950-962.
Score: 0.006
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Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits. Am J Hum Genet. 2023 01 05; 110(1):44-57.
Score: 0.006
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Discerning asthma endotypes through comorbidity mapping. Nat Commun. 2022 11 07; 13(1):6712.
Score: 0.006
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Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region. Genome Med. 2022 05 24; 14(1):55.
Score: 0.006
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Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program. Am J Hum Genet. 2022 05 05; 109(5):857-870.
Score: 0.006
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Protein prediction for trait mapping in diverse populations. PLoS One. 2022; 17(2):e0264341.
Score: 0.006
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Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. 2021 05 13; 184(10):2633-2648.e19.
Score: 0.006
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A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction. Nat Commun. 2021 03 03; 12(1):1424.
Score: 0.006
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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci. Genome Biol. 2021 01 26; 22(1):49.
Score: 0.005
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Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations. Am J Hum Genet. 2021 01 07; 108(1):25-35.
Score: 0.005
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sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression. Genome Biol. 2020 09 11; 21(1):235.
Score: 0.005
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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx. Genome Biol. 2020 09 11; 21(1):233.
Score: 0.005
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The impact of sex on gene expression across human tissues. Science. 2020 09 11; 369(6509).
Score: 0.005
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Cell type-specific genetic regulation of gene expression across human tissues. Science. 2020 09 11; 369(6509).
Score: 0.005
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Transcriptomic signatures across human tissues identify functional rare genetic variation. Science. 2020 09 11; 369(6509).
Score: 0.005
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CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses. Nat Commun. 2020 08 21; 11(1):4208.
Score: 0.005
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Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts. Cell Rep. 2020 06 02; 31(9):107716.
Score: 0.005
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Genetic regulatory variation in populations informs transcriptome analysis in rare disease. Science. 2019 10 18; 366(6463):351-356.
Score: 0.005
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Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. Hum Mol Genet. 2019 04 01; 28(7):1212-1224.
Score: 0.005
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Opportunities and challenges for transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):592-599.
Score: 0.005
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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nat Genet. 2019 04; 51(4):659-674.
Score: 0.005
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Genetic architecture of gene expression traits across diverse populations. PLoS Genet. 2018 08; 14(8):e1007586.
Score: 0.005
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Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nat Commun. 2018 07 30; 9(1):2976.
Score: 0.005
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A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. Cancer Res. 2018 09 15; 78(18):5419-5430.
Score: 0.005
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2017 12 19; 4:170179.
Score: 0.004
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Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer. PLoS Genet. 2017 Sep; 13(9):e1006727.
Score: 0.004
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A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet. 2017 10; 136(10):1363-1373.
Score: 0.004
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Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet. 2017 Jun; 49(6):834-841.
Score: 0.004
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017 07; 66(7):2019-2032.
Score: 0.004
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The genetic architecture of type 2 diabetes. Nature. 2016 08 04; 536(7614):41-47.
Score: 0.004
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Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx. Am J Hum Genet. 2016 Apr 07; 98(4):697-708.
Score: 0.004
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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype. Cancer Biol Ther. 2016; 17(1):91-103.
Score: 0.004
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MicroRNA biogenesis and cellular proliferation. Transl Res. 2015 Aug; 166(2):145-51.
Score: 0.004
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015 Jan; 11(1):e1004876.
Score: 0.004
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Genome-wide interrogation of longitudinal FEV1 in children with asthma. Am J Respir Crit Care Med. 2014 Sep 15; 190(6):619-27.
Score: 0.004
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Establishment of CYP2D6 reference samples by multiple validated genotyping platforms. Pharmacogenomics J. 2014 Dec; 14(6):564-72.
Score: 0.003
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Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38.
Score: 0.003
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Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity. BMC Genomics. 2014 Apr 16; 15:292.
Score: 0.003
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Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy. PLoS Genet. 2014 Apr; 10(4):e1004192.
Score: 0.003
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The impact of microRNA expression on cellular proliferation. Hum Genet. 2014 Jul; 133(7):931-8.
Score: 0.003
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Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients. Clin Pharmacol Ther. 2014 Jun; 95(6):644-52.
Score: 0.003
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Association of body mass index and outcomes after major lung resection. Eur J Cardiothorac Surg. 2014 Apr; 45(4):e94-9; discussion e99.
Score: 0.003
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EPS8 inhibition increases cisplatin sensitivity in lung cancer cells. PLoS One. 2013; 8(12):e82220.
Score: 0.003
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Genetic and epigenetic variants contributing to clofarabine cytotoxicity. Hum Mol Genet. 2013 Oct 01; 22(19):4007-20.
Score: 0.003
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Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients. Blood. 2013 May 23; 121(21):4366-76.
Score: 0.003
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Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation. Ann Oncol. 2013 Jul; 24(7):1867-1873.
Score: 0.003
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Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival. J Natl Cancer Inst. 2013 Feb 20; 105(4):302-9.
Score: 0.003
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Functional consequences of PRPF39 on distant genes and cisplatin sensitivity. Hum Mol Genet. 2012 Oct 01; 21(19):4348-55.
Score: 0.003
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Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel. Pharmacogenet Genomics. 2012 Jul; 22(7):498-507.
Score: 0.003
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Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. Am J Hum Genet. 2012 Jun 08; 90(6):1046-63.
Score: 0.003
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Identification of novel germline polymorphisms governing capecitabine sensitivity. Cancer. 2012 Aug 15; 118(16):4063-73.
Score: 0.003
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An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers. Hum Mol Genet. 2012 Apr 01; 21(7):1470-80.
Score: 0.003
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Population differences in microRNA expression and biological implications. RNA Biol. 2011 Jul-Aug; 8(4):692-701.
Score: 0.003
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Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients. Clin Cancer Res. 2011 Aug 15; 17(16):5490-500.
Score: 0.003
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Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers. Transl Res. 2011 May; 157(5):265-72.
Score: 0.003
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Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity. Mol Cancer Ther. 2011 Mar; 10(3):472-80.
Score: 0.003
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Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis. Clin Cancer Res. 2011 Feb 01; 17(3):459-71.
Score: 0.003
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Exprtarget: an integrative approach to predicting human microRNA targets. PLoS One. 2010 Oct 21; 5(10):e13534.
Score: 0.003