The University of Chicago Header Logo

Connection

David Grdina to Mercaptoethylamines

Back to Details
This is a "connection" page, showing publications David Grdina has written about Mercaptoethylamines.
David Grdina
Connection Strength
5.026
Mercaptoethylamines
  1. SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic Biol Med. 2011 Nov 15; 51(10):1918-25.
    View in: PubMed
    Score: 0.380
  2. SOD2-mediated effects induced by WR1065 and low-dose ionizing radiation on micronucleus formation in RKO human colon carcinoma cells. Radiat Res. 2011 Jan; 175(1):57-65.
    View in: PubMed
    Score: 0.359
  3. Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha. Radiat Res. 2007 Apr; 167(4):465-74.
    View in: PubMed
    Score: 0.280
  4. Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065. Free Radic Biol Med. 2006 Mar 15; 40(6):1004-16.
    View in: PubMed
    Score: 0.255
  5. Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC). Int J Radiat Oncol Biol Phys. 2004 Oct 01; 60(2):553-63.
    View in: PubMed
    Score: 0.235
  6. Delayed cytoprotection after enhancement of Sod2 (MnSOD) gene expression in SA-NH mouse sarcoma cells exposed to WR-1065, the active metabolite of amifostine. Radiat Res. 2002 Jul; 158(1):101-9.
    View in: PubMed
    Score: 0.201
  7. Relationships between cytoprotection and mutation prevention by WR-1065. Mil Med. 2002 Feb; 167(2 Suppl):51-3.
    View in: PubMed
    Score: 0.196
  8. Differential activation of nuclear transcription factor kappaB, gene expression, and proteins by amifostine's free thiol in human microvascular endothelial and glioma cells. Semin Radiat Oncol. 2002 Jan; 12(1 Suppl 1):103-11.
    View in: PubMed
    Score: 0.195
  9. Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines. Int J Radiat Biol. 2000 May; 76(5):633-9.
    View in: PubMed
    Score: 0.173
  10. Further evidence that the radioprotective aminothiol, WR-1065, catalytically inactivates mammalian topoisomerase II. Cancer Res. 2000 Mar 01; 60(5):1186-8.
    View in: PubMed
    Score: 0.171
  11. WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells. Cell Prolif. 1997 Jun-Jul; 30(6-7):283-94.
    View in: PubMed
    Score: 0.142
  12. The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065. Mutat Res. 1996 Sep 23; 356(2):147-54.
    View in: PubMed
    Score: 0.135
  13. Expression of thymidine kinase messenger RNA and a related transcript is modulated by radioprotector WR1065. Cancer Res. 1995 Nov 01; 55(21):4788-92.
    View in: PubMed
    Score: 0.127
  14. The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention. Carcinogenesis. 1995 Nov; 16(11):2699-705.
    View in: PubMed
    Score: 0.127
  15. Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278). Mutagenesis. 1994 Jul; 9(4):355-60.
    View in: PubMed
    Score: 0.116
  16. Inhibition of topoisomerase II alpha activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065). Radiat Res. 1994 Apr; 138(1):44-52.
    View in: PubMed
    Score: 0.114
  17. A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb; 179(2):115-24.
    View in: PubMed
    Score: 0.104
  18. Reversion of radiosensitivity in azacytidine-treated XRS5 cells does not result in full radioprotection by WR-1065. Int J Radiat Oncol Biol Phys. 1992; 23(5):999-1002.
    View in: PubMed
    Score: 0.097
  19. Chemical protection and cell-cycle effects on radiation-induced mutagenesis. Cell Prolif. 1992 Jan; 25(1):23-9.
    View in: PubMed
    Score: 0.097
  20. The effect of chemical radiation protectors on cell cycle progression after gamma or neutron irradiation. Cell Prolif. 1991 May; 24(3):271-80.
    View in: PubMed
    Score: 0.093
  21. Association of WR-1065 with CHO AA8 cells, nuclei, and nucleoids. Radiat Res. 1991 Feb; 125(2):152-7.
    View in: PubMed
    Score: 0.091
  22. Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells. Radiat Res. 2010 Feb; 173(2):175-83.
    View in: PubMed
    Score: 0.085
  23. Protection by WR1065 and WR151326 against fission-neutron-induced mutations at the HGPRT locus in V79 cells. Radiat Res. 1989 Mar; 117(3):500-10.
    View in: PubMed
    Score: 0.080
  24. Amifostine induces antioxidant enzymatic activities in normal tissues and a transplantable tumor that can affect radiation response. Int J Radiat Oncol Biol Phys. 2009 Mar 01; 73(3):886-96.
    View in: PubMed
    Score: 0.080
  25. Protection against radiation-induced mutagenesis in V79 cells by 2-[(aminopropyl)amino] ethanethiol under conditions of acute hypoxia. Radiat Res. 1989 Feb; 117(2):251-8.
    View in: PubMed
    Score: 0.079
  26. The effect of 2-[(aminopropyl)amino] ethanethiol on fission-neutron-induced DNA damage and repair. Br J Cancer. 1989 Jan; 59(1):17-21.
    View in: PubMed
    Score: 0.079
  27. WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability. Free Radic Biol Med. 2008 Dec 15; 45(12):1674-81.
    View in: PubMed
    Score: 0.077
  28. Cell cycle redistribution of cultured cells after treatment with chemical radiation protectors. Cell Tissue Kinet. 1988 May; 21(3):193-200.
    View in: PubMed
    Score: 0.075
  29. 2-[(Aminopropyl)amino] ethanethiol-mediated reductions in 60Co gamma-ray and fission-spectrum neutron-induced chromosome damage in V79 cells. Radiat Res. 1988 Jan; 113(1):145-54.
    View in: PubMed
    Score: 0.074
  30. The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells. Br J Cancer. 1987 May; 55(5):477-82.
    View in: PubMed
    Score: 0.070
  31. The effect of 2-[(aminopropyl)amino] ethanethiol (WR1065) on radiation-induced DNA damage and repair and cell progression in V79 cells. Br J Cancer. 1986 Dec; 54(6):933-41.
    View in: PubMed
    Score: 0.068
  32. Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells. Int J Radiat Oncol Biol Phys. 1986 Aug; 12(8):1475-8.
    View in: PubMed
    Score: 0.067
  33. 2-[(Aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Co gamma-ray irradiation. Carcinogenesis. 1986 Apr; 7(4):665-8.
    View in: PubMed
    Score: 0.065
  34. Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol. Cancer Res. 1986 Mar; 46(3):1132-5.
    View in: PubMed
    Score: 0.065
  35. The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells. Carcinogenesis. 1985 Jun; 6(6):929-31.
    View in: PubMed
    Score: 0.062
  36. Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res. 2004 Nov; 162(5):536-46.
    View in: PubMed
    Score: 0.059
  37. Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine. Int J Radiat Oncol Biol Phys. 2002 May 01; 53(1):180-9.
    View in: PubMed
    Score: 0.050
  38. Inhibition of spontaneous metastases formation by amifostine. Int J Cancer. 2002 Jan 10; 97(2):135-41.
    View in: PubMed
    Score: 0.049
  39. Activation of NFkappaB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells. Free Radic Biol Med. 2001 Jun 15; 30(12):1426-39.
    View in: PubMed
    Score: 0.047
  40. Effects of growth media on cell cycle progression in CHO cells exposed to the radioprotector WR-1065. Cell Prolif. 1992 Nov; 25(6):643-50.
    View in: PubMed
    Score: 0.026
  41. Accumulation of CHO cells in G2 phase following exposure to WR-1065. Radiat Res. 1991 May; 126(2):223-8.
    View in: PubMed
    Score: 0.023
  42. Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065. Br J Cancer. 1989 Dec; 60(6):893-6.
    View in: PubMed
    Score: 0.021
  43. Radioprotectors in treatment therapy to reduce risk in secondary tumor induction. Pharmacol Ther. 1988; 39(1-3):21-5.
    View in: PubMed
    Score: 0.018
  44. Effects of radioprotectors on DNA damage and repair, proteins, and cell-cycle progression. Pharmacol Ther. 1988; 39(1-3):133-7.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.