Marsha Rosner to Insulysin
This is a "connection" page, showing publications Marsha Rosner has written about Insulysin.
Connection Strength
1.992
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Functional human insulin-degrading enzyme can be expressed in bacteria. Protein Expr Purif. 2000 Jun; 19(1):91-8.
Score: 0.181
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Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation. Endocrinology. 1997 Aug; 138(8):3444-51.
Score: 0.148
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Identification of zinc ligands of the insulin-degrading enzyme. J Biol Chem. 1994 Dec 30; 269(52):33140-5.
Score: 0.124
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Functional analysis of conserved residues in the active site of insulin-degrading enzyme. J Biol Chem. 1993 Oct 15; 268(29):21538-44.
Score: 0.114
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Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding. J Biol Chem. 1993 Apr 15; 268(11):7943-8.
Score: 0.110
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Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology. 1993 Feb; 132(2):604-11.
Score: 0.109
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Regulation of insulin degradation: expression of an evolutionarily conserved insulin-degrading enzyme increases degradation via an intracellular pathway. Mol Endocrinol. 1991 Oct; 5(10):1467-76.
Score: 0.099
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Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme. Mol Endocrinol. 1990 Oct; 4(10):1580-91.
Score: 0.092
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An evolutionarily conserved TGF-alpha/insulin-degrading enzyme. Mol Reprod Dev. 1990 Sep; 27(1):54-9.
Score: 0.092
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An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin. J Cell Biol. 1989 Sep; 109(3):1301-7.
Score: 0.086
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Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme. FASEB J. 2009 Nov; 23(11):3734-42.
Score: 0.085
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Drosophila insulin degrading enzyme and rat skeletal muscle insulin protease cleave insulin at similar sites. Biochemistry. 1989 Mar 21; 28(6):2471-7.
Score: 0.083
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Immunohistochemical evidence of ubiquitous distribution of the metalloendoprotease insulin-degrading enzyme (IDE; insulysin) in human non-malignant tissues and tumor cell lines. Biol Chem. 2008 Nov; 389(11):1441-5.
Score: 0.081
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Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues. Int J Mol Med. 2008 Oct; 22(4):421-31.
Score: 0.080
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Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster. Proc Natl Acad Sci U S A. 1988 May; 85(10):3469-73.
Score: 0.078
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Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels. Int J Oncol. 2007 Jan; 30(1):73-80.
Score: 0.071
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Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature. 2006 Oct 19; 443(7113):870-4.
Score: 0.070
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The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition. Biochem Biophys Res Commun. 2006 May 19; 343(4):1032-7.
Score: 0.067
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Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization. Biochem J. 2000 Oct 15; 351 Pt 2:509-16.
Score: 0.046
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Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci. 2000 Mar 01; 20(5):1657-65.
Score: 0.044
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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem. 1998 Dec 04; 273(49):32730-8.
Score: 0.041
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Identification of the cleavage sites of transforming growth factor alpha by insulin-degrading enzymes. Biochim Biophys Acta. 1997 Apr 04; 1338(2):207-14.
Score: 0.036
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Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J Biol Chem. 1994 Sep 09; 269(36):22599-606.
Score: 0.030
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Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23----q25. Cytogenet Cell Genet. 1991; 57(4):184-6.
Score: 0.024