Marsha Rosner to Humans
This is a "connection" page, showing publications Marsha Rosner has written about Humans.
Connection Strength
0.778
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Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019 04; 568(7751):254-258.
Score: 0.023
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Raf kinase inhibitor protein: lessons of a better way for ß-adrenergic receptor activation in the heart. J Physiol. 2017 06 15; 595(12):4073-4087.
Score: 0.020
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Gene expression in local stroma reflects breast tumor states and predicts patient outcome. Sci Rep. 2016 12 16; 6:39240.
Score: 0.020
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Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res. 2015 Oct 01; 75(19):4063-73.
Score: 0.018
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Raf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancer. Crit Rev Oncog. 2014; 19(6):447-54.
Score: 0.016
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RKIP structure drives its function: a three-state model for regulation of RKIP. Crit Rev Oncog. 2014; 19(6):483-8.
Score: 0.016
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A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients. PLoS One. 2013; 8(12):e82125.
Score: 0.016
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RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2. Oncogene. 2014 Jul 03; 33(27):3528-37.
Score: 0.016
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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5.
Score: 0.015
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A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer. PLoS One. 2012; 7(11):e49893.
Score: 0.015
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Identification of novel metastasis suppressor signaling pathways for breast cancer. Cell Cycle. 2012 Jul 01; 11(13):2452-7.
Score: 0.014
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Nonheritable cellular variability accelerates the evolutionary processes of cancer. PLoS Biol. 2012; 10(4):e1001296.
Score: 0.014
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Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J. 2011 Aug 26; 30(21):4500-14.
Score: 0.014
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Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. Oncogene. 2011 Nov 03; 30(44):4509-22.
Score: 0.013
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Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244. Amino Acids. 2010 Nov; 39(5):1487-92.
Score: 0.012
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MAP kinase regulation of the mitotic spindle checkpoint. Methods Mol Biol. 2010; 661:497-505.
Score: 0.012
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CDKs as therapeutic targets for the human genetic disease tuberous sclerosis? Eur J Clin Invest. 2009 Dec; 39(12):1033-5.
Score: 0.012
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A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis. Blood. 2009 Nov 12; 114(20):4592-600.
Score: 0.012
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MicroRNA-regulated feed forward loop network. Cell Cycle. 2009 Aug 15; 8(16):2477-8.
Score: 0.012
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Raf Kinase Inhibitory Protein protects cells against locostatin-mediated inhibition of migration. PLoS One. 2009 Jun 24; 4(6):e6028.
Score: 0.012
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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J. 2009 Feb 18; 28(4):347-58.
Score: 0.011
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A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Res. 2009 Jan 01; 69(1):65-74.
Score: 0.011
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Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Mol Cell Biol. 2009 Mar; 29(5):1306-20.
Score: 0.011
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Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target. Expert Opin Ther Targets. 2008 Oct; 12(10):1275-87.
Score: 0.011
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Tuberin, p27 and mTOR in different cells. Amino Acids. 2009 Feb; 36(2):297-302.
Score: 0.011
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Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Res. 2008 Apr; 18(4):452-7.
Score: 0.011
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Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. J Biol Chem. 2007 Jul 06; 282(27):19781-7.
Score: 0.010
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Cytoplasmic/nuclear localization of tuberin in different cell lines. Amino Acids. 2007 Nov; 33(4):575-9.
Score: 0.010
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Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell. 2006 Aug; 23(4):561-74.
Score: 0.010
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Akt regulates nuclear/cytoplasmic localization of tuberin. Oncogene. 2007 Jan 25; 26(4):521-31.
Score: 0.009
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Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase. Cancer Res. 2006 Jun 15; 66(12):6296-303.
Score: 0.009
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Tuberin activates the proapoptotic molecule BAD. Oncogene. 2006 Oct 19; 25(49):6467-79.
Score: 0.009
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CDKL5/Stk9 kinase inactivation is associated with neuronal developmental disorders. Hum Mol Genet. 2005 Dec 15; 14(24):3775-86.
Score: 0.009
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Anthrax edema factor potency depends on mode of cell entry. Biochem Biophys Res Commun. 2005 Sep 30; 335(3):850-7.
Score: 0.009
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14-3-3 proteins are involved in the regulation of mammalian cell proliferation. Amino Acids. 2006 Feb; 30(1):105-9.
Score: 0.009
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Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. J Biol Chem. 2005 Jul 01; 280(26):24931-40.
Score: 0.009
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Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein. Cell Res. 2005 Jan; 15(1):19-23.
Score: 0.009
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Proteins interacting with the tuberous sclerosis gene products. Amino Acids. 2004 Oct; 27(2):119-28.
Score: 0.008
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ERK7 expression and kinase activity is regulated by the ubiquitin-proteosome pathway. J Biol Chem. 2004 May 28; 279(22):23073-81.
Score: 0.008
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Nonmonotone invasion landscape by noise-aware control of metastasis activator levels. Nat Chem Biol. 2023 07; 19(7):887-899.
Score: 0.008
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Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem. 2003 Apr 11; 278(15):13061-8.
Score: 0.007
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SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells. mBio. 2022 10 26; 13(5):e0241522.
Score: 0.007
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Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2121867119.
Score: 0.007
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Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation. J Neurochem. 2002 Jun; 81(5):922-34.
Score: 0.007
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ERK8, a new member of the mitogen-activated protein kinase family. J Biol Chem. 2002 May 10; 277(19):16733-43.
Score: 0.007
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Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses. Sci Adv. 2022 Feb 25; 8(8):eabi6110.
Score: 0.007
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New strategies for targeting kinase networks in cancer. J Biol Chem. 2021 10; 297(4):101128.
Score: 0.007
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Limited inhibition of multiple nodes in a driver network blocks metastasis. Elife. 2021 05 11; 10.
Score: 0.007
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Cloning and characterization of MST4, a novel Ste20-like kinase. J Biol Chem. 2001 Jun 22; 276(25):22439-45.
Score: 0.007
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A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity. Mol Cell Biol. 2001 Mar; 21(6):2235-47.
Score: 0.007
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The TSC1 gene product, hamartin, negatively regulates cell proliferation. Hum Mol Genet. 2000 Jul 22; 9(12):1721-7.
Score: 0.006
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Functional human insulin-degrading enzyme can be expressed in bacteria. Protein Expr Purif. 2000 Jun; 19(1):91-8.
Score: 0.006
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Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. J Exp Med. 2019 06 03; 216(6):1345-1358.
Score: 0.006
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Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. J Biol Chem. 1999 Jan 15; 274(3):1621-7.
Score: 0.006
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Raf and fibroblast growth factor phosphorylate Elk1 and activate the serum response element of the immediate early gene pip92 by mitogen-activated protein kinase-independent as well as -dependent signaling pathways. Mol Cell Biol. 1998 Apr; 18(4):2272-81.
Score: 0.005
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Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13453-13458.
Score: 0.005
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Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation. Endocrinology. 1997 Aug; 138(8):3444-51.
Score: 0.005
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Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line. J Neurochem. 1996 Nov; 67(5):1908-20.
Score: 0.005
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Interaction of tRNA with MEK2 in pancreatic cancer cells. Sci Rep. 2016 06 15; 6:28260.
Score: 0.005
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Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Mol Cell Biol. 1996 Apr; 16(4):1458-70.
Score: 0.005
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Noise-Driven Phenotypic Heterogeneity with Finite Correlation Time in Clonal Populations. PLoS One. 2015; 10(7):e0132397.
Score: 0.004
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Identification of zinc ligands of the insulin-degrading enzyme. J Biol Chem. 1994 Dec 30; 269(52):33140-5.
Score: 0.004
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Conceptualizing cancer drugs as classifiers. PLoS One. 2014; 9(9):e106444.
Score: 0.004
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Induction of epidermal growth factor receptor gene transcription by transforming growth factor beta 1: association with loss of protein binding to a negative regulatory element. Cell Growth Differ. 1994 Aug; 5(8):801-9.
Score: 0.004
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Patient dissatisfaction after functionally successful conjunctivodacryocystorhinostomy with Jones tube. Am J Ophthalmol. 1994 May 15; 117(5):636-42.
Score: 0.004
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Identification of an epidermal growth factor receptor transcriptional repressor. J Biol Chem. 1994 Feb 11; 269(6):4307-12.
Score: 0.004
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Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):E364-73.
Score: 0.004
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Functional analysis of conserved residues in the active site of insulin-degrading enzyme. J Biol Chem. 1993 Oct 15; 268(29):21538-44.
Score: 0.004
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Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding. J Biol Chem. 1993 Apr 15; 268(11):7943-8.
Score: 0.004
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RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy. PLoS One. 2013; 8(3):e59104.
Score: 0.004
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Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. RNA. 2013 Apr; 19(4):461-6.
Score: 0.004
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Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology. 1993 Feb; 132(2):604-11.
Score: 0.004
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Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor. J Biol Chem. 1992 Oct 05; 267(28):19876-83.
Score: 0.004
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Anti-tumor effects of an engineered "killer" transfer RNA. Biochem Biophys Res Commun. 2012 Oct 12; 427(1):148-53.
Score: 0.004
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Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity. Toxicon. 1992 Aug; 30(8):873-8.
Score: 0.004
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Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. PLoS One. 2012; 7(1):e30769.
Score: 0.003
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An integrated view of cyclin E function and regulation. Cell Cycle. 2012 Jan 01; 11(1):57-64.
Score: 0.003
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Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure. Amino Acids. 2012 Aug; 43(2):937-49.
Score: 0.003
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Regulation of insulin degradation: expression of an evolutionarily conserved insulin-degrading enzyme increases degradation via an intracellular pathway. Mol Endocrinol. 1991 Oct; 5(10):1467-76.
Score: 0.003
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p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6. Amino Acids. 2012 Jun; 42(6):2251-6.
Score: 0.003
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Regulation of insulin, epidermal growth factor, and transforming growth factor-alpha levels by growth factor-degrading enzymes. Endocrinology. 1991 Mar; 128(3):1603-10.
Score: 0.003
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Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme. Mol Endocrinol. 1990 Oct; 4(10):1580-91.
Score: 0.003
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Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. Mol Cancer Ther. 2010 Oct; 9(10):2814-24.
Score: 0.003
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An evolutionarily conserved TGF-alpha/insulin-degrading enzyme. Mol Reprod Dev. 1990 Sep; 27(1):54-9.
Score: 0.003
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Different cytoplasmic/nuclear distribution of S6 protein phosphorylated at S240/244 and S235/236. Amino Acids. 2011 Feb; 40(2):595-600.
Score: 0.003
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Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands. PLoS One. 2010 May 05; 5(5):e10479.
Score: 0.003
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Regulation of the epidermal growth factor receptor by growth-modulating agents: effects of staurosporine, a protein kinase inhibitor. Cancer Res. 1990 Feb 01; 50(3):533-8.
Score: 0.003
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Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature. 2009 Nov 26; 462(7272):522-6.
Score: 0.003
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Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Oncogene. 2010 Feb 18; 29(7):966-77.
Score: 0.003
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tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Res. 2009 Nov; 37(21):7268-80.
Score: 0.003
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Basic and acidic fibroblast growth factors modulate the epidermal growth factor receptor by a protein kinase C-independent pathway. Biochem Biophys Res Commun. 1989 Oct 31; 164(2):796-803.
Score: 0.003
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Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters. Proc Natl Acad Sci U S A. 1989 Feb; 86(3):812-6.
Score: 0.003
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mTOR phosphorylated at S2448 binds to raptor and rictor. Amino Acids. 2010 Jan; 38(1):223-8.
Score: 0.003
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Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669. Biochem Biophys Res Commun. 1988 Dec 15; 157(2):740-6.
Score: 0.003
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Immunohistochemical evidence of ubiquitous distribution of the metalloendoprotease insulin-degrading enzyme (IDE; insulysin) in human non-malignant tissues and tumor cell lines. Biol Chem. 2008 Nov; 389(11):1441-5.
Score: 0.003
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Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues. Int J Mol Med. 2008 Oct; 22(4):421-31.
Score: 0.003
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Intratumoral IGF-I protein expression is selectively upregulated in breast cancer patients with BRCA1/2 mutations. Endocr Relat Cancer. 2007 Dec; 14(4):1053-62.
Score: 0.003
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Ras mediates cell survival by regulating tuberin. Oncogene. 2008 Mar 27; 27(14):2072-83.
Score: 0.003
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Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels. Int J Oncol. 2007 Jan; 30(1):73-80.
Score: 0.002
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Characterization of rodent epidermal growth factor receptor transcripts using a mouse genomic probe. Biochem Biophys Res Commun. 1986 Dec 30; 141(3):1109-15.
Score: 0.002
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Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature. 2006 Oct 19; 443(7113):870-4.
Score: 0.002
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The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition. Biochem Biophys Res Commun. 2006 May 19; 343(4):1032-7.
Score: 0.002
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Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor. J Biol Chem. 1984 Oct 25; 259(20):12502-7.
Score: 0.002
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Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor. Proc Natl Acad Sci U S A. 1984 May; 81(10):3034-8.
Score: 0.002
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Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. Am J Respir Crit Care Med. 2004 Mar 15; 169(6):703-11.
Score: 0.002
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The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol. 2002 Dec; 22(24):8571-9.
Score: 0.002
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Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta. Am J Respir Cell Mol Biol. 2002 Aug; 27(2):204-13.
Score: 0.002
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Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression. Oncogene. 2001 Aug 09; 20(35):4904-9.
Score: 0.002
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Tuberous sclerosis gene products in proliferation control. Mutat Res. 2001 Jul; 488(3):233-9.
Score: 0.002
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Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization. Biochem J. 2000 Oct 15; 351 Pt 2:509-16.
Score: 0.002
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Insulin-like growth factor I receptor signaling in differentiation of neuronal H19-7 cells. Cancer Res. 2000 Apr 15; 60(8):2263-72.
Score: 0.002
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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem. 1998 Dec 04; 273(49):32730-8.
Score: 0.001
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WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. EMBO J. 1995 Oct 02; 14(19):4662-75.
Score: 0.001
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Hydrogen peroxide stimulates mitogen-activated protein kinase in bovine tracheal myocytes: implications for human airway disease. Am J Respir Cell Mol Biol. 1994 Nov; 11(5):577-85.
Score: 0.001
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Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J Biol Chem. 1994 Sep 09; 269(36):22599-606.
Score: 0.001
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Adenovirus and protein kinase C have distinct molecular requirements for regulating epidermal growth factor receptor trafficking. J Cell Physiol. 1993 Dec; 157(3):535-43.
Score: 0.001
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Interactions between retroviruses and environmental carcinogens and their role in animal and human leukemogenesis. Leuk Res. 1992 Nov; 16(11):1061-9.
Score: 0.001
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Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23----q25. Cytogenet Cell Genet. 1991; 57(4):184-6.
Score: 0.001
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Substance abuse in pregnant women: recent experience at the Perinatal Center for Chemical Dependence of Northwestern Memorial Hospital. Obstet Gynecol. 1989 May; 73(5 Pt 1):715-20.
Score: 0.001