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Connection

Simon Hayward to Prostatic Neoplasms

This is a "connection" page, showing publications Simon Hayward has written about Prostatic Neoplasms.
Connection Strength

3.710
  1. Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment. Prostate. 2020 02; 80(2):173-185.
    View in: PubMed
    Score: 0.295
  2. Tyrosine kinase inhibitor therapy prescribed for non-urologic diseases can modify PSA titers in urology patients. Prostate. 2019 02; 79(3):259-264.
    View in: PubMed
    Score: 0.274
  3. Interaction of prostate carcinoma-associated fibroblasts with human epithelial cell lines in vivo. Differentiation. 2017 Jul - Aug; 96:40-48.
    View in: PubMed
    Score: 0.251
  4. Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. Prostate. 2013 Apr; 73(5):476-88.
    View in: PubMed
    Score: 0.180
  5. Targeting the tumor stroma as a novel therapeutic approach for prostate cancer. Adv Pharmacol. 2012; 65:267-313.
    View in: PubMed
    Score: 0.171
  6. Altered TGF-ß signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. Cancer Res. 2011 Feb 15; 71(4):1272-81.
    View in: PubMed
    Score: 0.161
  7. Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer. PLoS One. 2009 Dec 21; 4(12):e8384.
    View in: PubMed
    Score: 0.148
  8. Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression. Cancer Res. 2007 Sep 01; 67(17):8188-97.
    View in: PubMed
    Score: 0.127
  9. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 2007 May 01; 67(9):4244-53.
    View in: PubMed
    Score: 0.124
  10. Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma. Lab Invest. 2005 Sep; 85(9):1086-103.
    View in: PubMed
    Score: 0.110
  11. Development and characterization of efficient xenograft models for benign and malignant human prostate tissue. Prostate. 2005 Jul 01; 64(2):149-59.
    View in: PubMed
    Score: 0.109
  12. Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. Prostate. 2005 Jun 01; 63(4):369-84.
    View in: PubMed
    Score: 0.108
  13. Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues. Development. 2023 07 01; 150(13).
    View in: PubMed
    Score: 0.095
  14. Fibroblast heterogeneity in prostate carcinogenesis. Cancer Lett. 2022 01 28; 525:76-83.
    View in: PubMed
    Score: 0.084
  15. Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Lab Invest. 2021 07; 101(7):921-934.
    View in: PubMed
    Score: 0.081
  16. Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression. Nat Ecol Evol. 2020 06; 4(6):870-884.
    View in: PubMed
    Score: 0.076
  17. Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF. Lab Invest. 2019 12; 99(12):1822-1834.
    View in: PubMed
    Score: 0.072
  18. Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse. Prostate. 2019 06; 79(9):980-993.
    View in: PubMed
    Score: 0.071
  19. DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130. Sci Rep. 2019 02 28; 9(1):3035.
    View in: PubMed
    Score: 0.070
  20. PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts. J Cell Sci. 2018 07 11; 131(13).
    View in: PubMed
    Score: 0.067
  21. Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. J Cell Biol. 2017 11 06; 216(11):3799-3816.
    View in: PubMed
    Score: 0.064
  22. Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations. Mol Cancer Res. 2016 Apr; 14(4):374-84.
    View in: PubMed
    Score: 0.056
  23. Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016 Mar; 157(3):1094-109.
    View in: PubMed
    Score: 0.056
  24. Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion. J Biol Chem. 2015 Mar 27; 290(13):8271-82.
    View in: PubMed
    Score: 0.053
  25. Stromal androgen receptor in prostate development and cancer. Am J Pathol. 2014 Oct; 184(10):2598-607.
    View in: PubMed
    Score: 0.051
  26. ALCAM/CD166 is a TGF-ß-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Res. 2014 Mar 01; 74(5):1404-15.
    View in: PubMed
    Score: 0.049
  27. Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1. Dis Model Mech. 2013 Mar; 6(2):530-6.
    View in: PubMed
    Score: 0.045
  28. The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor. Mol Cell Biol. 2012 Aug; 32(16):3190-202.
    View in: PubMed
    Score: 0.044
  29. Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis. Carcinogenesis. 2012 Jul; 33(7):1391-8.
    View in: PubMed
    Score: 0.044
  30. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. J Clin Invest. 2012 May; 122(5):1907-19.
    View in: PubMed
    Score: 0.044
  31. Role for stromal heterogeneity in prostate tumorigenesis. Cancer Res. 2011 May 15; 71(10):3459-70.
    View in: PubMed
    Score: 0.041
  32. E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):704-9.
    View in: PubMed
    Score: 0.040
  33. Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia. Prostate. 2011 Feb 15; 71(3):305-17.
    View in: PubMed
    Score: 0.039
  34. The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Res. 2009 Sep 01; 69(17):7111-20.
    View in: PubMed
    Score: 0.036
  35. Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. Prostate. 2009 Mar 01; 69(4):428-42.
    View in: PubMed
    Score: 0.035
  36. A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells. PLoS One. 2008 Jul 02; 3(7):e2572.
    View in: PubMed
    Score: 0.034
  37. Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity. Cancer Res. 2008 Jun 15; 68(12):4709-18.
    View in: PubMed
    Score: 0.033
  38. Down-regulation of p57Kip2 induces prostate cancer in the mouse. Cancer Res. 2008 May 15; 68(10):3601-8.
    View in: PubMed
    Score: 0.033
  39. Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer. Lab Invest. 2006 Oct; 86(10):1074-88.
    View in: PubMed
    Score: 0.029
  40. Steroid hormones stimulate human prostate cancer progression and metastasis. Int J Cancer. 2006 May 01; 118(9):2123-31.
    View in: PubMed
    Score: 0.029
  41. Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer. Cancer Res. 2005 Nov 15; 65(22):10423-30.
    View in: PubMed
    Score: 0.028
  42. An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Lab Invest. 2005 Nov; 85(11):1392-404.
    View in: PubMed
    Score: 0.028
  43. NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice. Cancer Res. 2004 Aug 01; 64(15):5489-95.
    View in: PubMed
    Score: 0.026
  44. Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion. Cancer Lett. 2004 Apr 15; 207(1):79-87.
    View in: PubMed
    Score: 0.025
  45. Role of the stromal microenvironment in carcinogenesis of the prostate. Int J Cancer. 2003 Oct 20; 107(1):1-10.
    View in: PubMed
    Score: 0.024
  46. Rescue and isolation of Rb-deficient prostate epithelium by tissue recombination. Methods Mol Biol. 2003; 218:17-33.
    View in: PubMed
    Score: 0.023
  47. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res. 2002 Jun 01; 62(11):2999-3004.
    View in: PubMed
    Score: 0.022
  48. Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis. J Biol Chem. 2002 Nov 15; 277(46):44475-84.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.