Simon Hayward to Humans
This is a "connection" page, showing publications Simon Hayward has written about Humans.
Connection Strength
0.480
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TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease. Nat Commun. 2022 04 19; 13(1):2133.
Score: 0.025
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Immunotherapeutic Response in Tumors Is Affected by Microenvironmental ROS. Cancer Res. 2020 05 01; 80(9):1799-1800.
Score: 0.022
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Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment. Prostate. 2020 02; 80(2):173-185.
Score: 0.021
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Tyrosine kinase inhibitor therapy prescribed for non-urologic diseases can modify PSA titers in urology patients. Prostate. 2019 02; 79(3):259-264.
Score: 0.020
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Interaction of prostate carcinoma-associated fibroblasts with human epithelial cell lines in vivo. Differentiation. 2017 Jul - Aug; 96:40-48.
Score: 0.018
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Review of Prostate Anatomy and Embryology and the Etiology of Benign Prostatic Hyperplasia. Urol Clin North Am. 2016 Aug; 43(3):279-88.
Score: 0.017
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Altered TGF-a/ß signaling drives cooperation between breast cancer cell populations. FASEB J. 2016 10; 30(10):3441-3452.
Score: 0.017
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NF-?B and androgen receptor variant 7 induce expression of SRD5A isoforms and confer 5ARI resistance. Prostate. 2016 08; 76(11):1004-18.
Score: 0.017
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NF-?B and androgen receptor variant expression correlate with human BPH progression. Prostate. 2016 Apr; 76(5):491-511.
Score: 0.016
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Isolation and analysis of discreet human prostate cellular populations. Differentiation. 2016 Apr-Jun; 91(4-5):139-51.
Score: 0.016
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Deficiency in metabolic regulators PPAR? and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. Am J Pathol. 2013 Feb; 182(2):449-59.
Score: 0.013
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Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. Prostate. 2013 Apr; 73(5):476-88.
Score: 0.013
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Targeting the tumor stroma as a novel therapeutic approach for prostate cancer. Adv Pharmacol. 2012; 65:267-313.
Score: 0.012
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PPAR?: a molecular link between systemic metabolic disease and benign prostate hyperplasia. Differentiation. 2011 Nov-Dec; 82(4-5):220-36.
Score: 0.012
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Altered TGF-ß signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. Cancer Res. 2011 Feb 15; 71(4):1272-81.
Score: 0.012
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Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells. Stem Cells. 2010 Feb; 28(2):344-56.
Score: 0.011
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Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer. PLoS One. 2009 Dec 21; 4(12):e8384.
Score: 0.011
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Cancer associated fibroblasts in cancer pathogenesis. Semin Cell Dev Biol. 2010 Feb; 21(1):33-9.
Score: 0.011
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Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression. Cancer Res. 2007 Sep 01; 67(17):8188-97.
Score: 0.009
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Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 2007 May 01; 67(9):4244-53.
Score: 0.009
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Development and characterization of efficient xenograft models for benign and malignant human prostate tissue. Prostate. 2005 Jul 01; 64(2):149-59.
Score: 0.008
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Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. Prostate. 2005 Jun 01; 63(4):369-84.
Score: 0.008
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Infiltrating lipid-rich macrophage subpopulations identified as a regulator of increasing prostate size in human benign prostatic hyperplasia. Front Immunol. 2024; 15:1494476.
Score: 0.008
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Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues. Development. 2023 07 01; 150(13).
Score: 0.007
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Quantitation of apoptotic activity following castration in human prostatic tissue in vivo. Prostate. 2003 Feb 15; 54(3):212-9.
Score: 0.007
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Fibroblast heterogeneity in prostate carcinogenesis. Cancer Lett. 2022 01 28; 525:76-83.
Score: 0.006
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Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Lab Invest. 2021 07; 101(7):921-934.
Score: 0.006
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Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression. Nat Ecol Evol. 2020 06; 4(6):870-884.
Score: 0.006
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Propagation of human prostate tissue from induced pluripotent stem cells. Stem Cells Transl Med. 2020 07; 9(7):734-745.
Score: 0.005
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Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF. Lab Invest. 2019 12; 99(12):1822-1834.
Score: 0.005
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DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130. Sci Rep. 2019 02 28; 9(1):3035.
Score: 0.005
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PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts. J Cell Sci. 2018 07 11; 131(13).
Score: 0.005
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Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. J Cell Biol. 2017 11 06; 216(11):3799-3816.
Score: 0.005
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A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Prostate. 2017 Aug; 77(11):1213-1220.
Score: 0.005
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Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ. Breast Cancer Res. 2017 05 15; 19(1):56.
Score: 0.004
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Genome-wide analysis of AR binding and comparison with transcript expression in primary human fetal prostate fibroblasts and cancer associated fibroblasts. Mol Cell Endocrinol. 2018 08 15; 471:1-14.
Score: 0.004
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Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo. Oncotarget. 2016 10 25; 7(43):70404-70419.
Score: 0.004
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Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations. Mol Cancer Res. 2016 Apr; 14(4):374-84.
Score: 0.004
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Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016 Mar; 157(3):1094-109.
Score: 0.004
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Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration. BMC Cancer. 2015 Aug 13; 15:584.
Score: 0.004
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Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. PLoS One. 2015; 10(4):e0122442.
Score: 0.004
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Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion. J Biol Chem. 2015 Mar 27; 290(13):8271-82.
Score: 0.004
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Stromal androgen receptor in prostate development and cancer. Am J Pathol. 2014 Oct; 184(10):2598-607.
Score: 0.004
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Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor network. Prostate. 2014 May; 74(6):669-79.
Score: 0.004
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ALCAM/CD166 is a TGF-ß-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Res. 2014 Mar 01; 74(5):1404-15.
Score: 0.004
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A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. Eur Urol. 2013 Nov; 64(5):753-61.
Score: 0.003
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Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1. Dis Model Mech. 2013 Mar; 6(2):530-6.
Score: 0.003
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The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor. Mol Cell Biol. 2012 Aug; 32(16):3190-202.
Score: 0.003
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Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. J Clin Invest. 2012 May; 122(5):1907-19.
Score: 0.003
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Role for stromal heterogeneity in prostate tumorigenesis. Cancer Res. 2011 May 15; 71(10):3459-70.
Score: 0.003
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E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):704-9.
Score: 0.003
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Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia. Prostate. 2011 Feb 15; 71(3):305-17.
Score: 0.003
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The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Res. 2009 Sep 01; 69(17):7111-20.
Score: 0.003
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Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. Prostate. 2009 Mar 01; 69(4):428-42.
Score: 0.003
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Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. J Biol Chem. 2008 Oct 10; 283(41):27957-27972.
Score: 0.002
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A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells. PLoS One. 2008 Jul 02; 3(7):e2572.
Score: 0.002
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Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity. Cancer Res. 2008 Jun 15; 68(12):4709-18.
Score: 0.002
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Down-regulation of p57Kip2 induces prostate cancer in the mouse. Cancer Res. 2008 May 15; 68(10):3601-8.
Score: 0.002
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Steroid hormones stimulate human prostate cancer progression and metastasis. Int J Cancer. 2006 May 01; 118(9):2123-31.
Score: 0.002
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Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer. Cancer Res. 2005 Nov 15; 65(22):10423-30.
Score: 0.002
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An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Lab Invest. 2005 Nov; 85(11):1392-404.
Score: 0.002
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NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice. Cancer Res. 2004 Aug 01; 64(15):5489-95.
Score: 0.002
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Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion. Cancer Lett. 2004 Apr 15; 207(1):79-87.
Score: 0.002
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Role of the stromal microenvironment in carcinogenesis of the prostate. Int J Cancer. 2003 Oct 20; 107(1):1-10.
Score: 0.002